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Rapacuronium bromide

Rapacuronium bromide (brand name Raplon) is a rapidly acting, non-depolarizing aminosteroid neuromuscular blocker formerly used in modern anaesthesia, to aid and enable endotracheal intubation, which is often necessary to assist in the controlled ventilation of unconscious patients during surgery and sometimes in intensive care. As a non-depolarizing…

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3D model (JSmol)
Interactive image
ATC code
none
Bioavailability
Not applicable
CAS Number
156137-99-4 N
ChEMBL
ChEMBL1201352 N
ChemSpider
4470889 Y

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Rapacuronium bromide

Nodes10
Edges9
Triples20
Avg. degree1.8
Density0.2
Components1

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Rapacuronium bromide

Top relations

3D model (JSmol) · 1
Rapacuronium bromide → Interactive image
ATC code · 1
Rapacuronium bromide → none
Bioavailability · 1
Rapacuronium bromide → Not applicable
CAS Number · 1
Rapacuronium bromide → 156137-99-4 N
ChEMBL · 1
Rapacuronium bromide → ChEMBL1201352 N
ChemSpider · 1
Rapacuronium bromide → 4470889 Y
CompTox Dashboard (EPA) · 1
Rapacuronium bromide → DTXSID7048823
DrugBank · 1
Rapacuronium bromide → DB04834 Y
ECHA InfoCard · 1
Rapacuronium bromide → 100.211.226
Elimination half-life · 1
Rapacuronium bromide → 141 minutes (mean)

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Important terminology

non-depolarizing rapacuronium bromide name withdrawn 27 aminosteroid anaesthesia bronchospasm organon brand raplon rapidly acting neuromuscular blocker formerly used modern aid

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Rapacuronium bromide3D model (JSmol)Interactive image1.00infobox
Rapacuronium bromideATC codenone1.00infobox
Rapacuronium bromideBioavailabilityNot applicable1.00infobox
Rapacuronium bromideCAS Number156137-99-4 N1.00infobox
Rapacuronium bromideChEMBLChEMBL1201352 N1.00infobox
Rapacuronium bromideChemSpider4470889 Y1.00infobox
Rapacuronium bromideCompTox Dashboard (EPA)DTXSID70488231.00infobox
Rapacuronium bromideDrugBankDB04834 Y1.00infobox
Rapacuronium bromideECHA InfoCard100.211.2261.00infobox
Rapacuronium bromideElimination half-life141 minutes (mean)1.00infobox
Rapacuronium bromideExcretionRenal and fecal1.00infobox
Rapacuronium bromideFormulaC37H61N2O4+1.00infobox
Rapacuronium bromideLegal statusUS: Withdrawn1.00infobox
Rapacuronium bromideMetabolismHydrolyzed to active metabolites CYP system not involved1.00infobox
Rapacuronium bromideMolar mass597.905 g·mol−11.00infobox
Rapacuronium bromideOther names[(2S, 3S, 5S, 8R, 9S, 10S, 13S, 14S, 16S, 17S)-3-acetyloxy-10,13-dimethyl-2-(1-piperidyl)-16-(1-prop-2-enyl-3,4,5,6-tetrahydro-2H-pyridin-1-yl)-2 ,3 ,4 ,5 ,6 ,7 ,8 ,9 ,11 ,12 ,1…1.00infobox
Rapacuronium bromideProtein bindingVariable1.00infobox
Rapacuronium bromidePubChem CID53113981.00infobox
Rapacuronium bromideRoutes of administrationIntravenous1.00infobox
Rapacuronium bromideUNII65Q4QDG4KC1.00infobox

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