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RAI1

Retinoic acid-induced protein 1 is a transcription factor that in humans is encoded by the RAI1 gene. Mutations or copy number alterations affecting this gene are associated with neurodevelopmental disorders. Deletions of RAI1 are a primary cause of Smith–Magenis syndrome, whereas duplications of the gene are associated with Potocki–Lupski syndrome.

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Aliases
RAI1, SMCR, SMS, retinoic acid induced 1
Band
17p11.2 · 11|11 B1.3-B2
Bgee
retinal pigment epithelium · nipple · palpebral conjunctiva · urethra · pylorus
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

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Map overview Semantic statistics

RAI1

Nodes8
Edges7
Triples79
Avg. degree1.75
Density0.25
Components1

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RAI1

Top relations

Bgee · 20
RAI1 → anterior amygdaloid area, Brodmann area 23, cardia, dorsomedial hypothalamic nucleus, habenula, human penis, lateral hypothalamus, lateral septal nucleus, mammillary body, nipple, olfactory tubercle, palpebral conjunctiva, parietal lobe, pylorus, retinal pigment epithelium, Rostral migratory stream, subiculum, tibia, urethra, ventromedial nucleus
RNA expression pattern · 20
RAI1 → anterior amygdaloid area, Brodmann area 23, cardia, dorsomedial hypothalamic nucleus, habenula, human penis, lateral hypothalamus, lateral septal nucleus, mammillary body, nipple, olfactory tubercle, palpebral conjunctiva, parietal lobe, pylorus, retinal pigment epithelium, Rostral migratory stream, subiculum, tibia, urethra, ventromedial nucleus
Gene ontology · 14
RAI1 → circadian regulation of gene expression, cytoplasm, DNA-binding transcription factor activity, metal ion binding, mitochondrion, negative regulation of multicellular organism growth, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, regulation of transcription by RNA polymerase II, rhythmic process, skeletal system development
related to External links · 5
RAI1 → GeneReviews/NIH/NCBI/UW, Medicine Medical Subject Headings, MeSH, National Library, Smith-Magenis SyndromeRAI1
Band · 2
RAI1 → 11|11 B1.3-B2, 17p11.2
Chr. · 2
RAI1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
RAI1 → 17,811,453 bp, 60,199,197 bp
Aliases · 1
RAI1 → RAI1, SMCR, SMS, retinoic acid induced 1
BioGPS · 1
RAI1 → n/a
Databases · 1
RAI1 → NCBI: entry; OMA: entry

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Important terminology

gene bp human chr band chromosome 17 retinoic protein location associated mouse transcription factor external syndrome 811 453 end 11

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RAI1AliasesRAI1, SMCR, SMS, retinoic acid induced 11.00infobox
RAI1Band17p11.21.00infobox
RAI1Band11|11 B1.3-B21.00infobox
RAI1Bgeeretinal pigment epithelium1.00infobox
RAI1Bgeenipple1.00infobox
RAI1Bgeepalpebral conjunctiva1.00infobox
RAI1Bgeeurethra1.00infobox
RAI1Bgeepylorus1.00infobox
RAI1Bgeetibia1.00infobox
RAI1BgeeBrodmann area 231.00infobox
RAI1Bgeecardia1.00infobox
RAI1Bgeehuman penis1.00infobox
RAI1Bgeeparietal lobe1.00infobox
RAI1Bgeelateral septal nucleus1.00infobox
RAI1Bgeehabenula1.00infobox
RAI1Bgeeanterior amygdaloid area1.00infobox
RAI1Bgeeolfactory tubercle1.00infobox
RAI1Bgeeventromedial nucleus1.00infobox
RAI1Bgeesubiculum1.00infobox
RAI1Bgeedorsomedial hypothalamic nucleus1.00infobox
RAI1BgeeRostral migratory stream1.00infobox
RAI1Bgeelateral hypothalamus1.00infobox
RAI1Bgeemammillary body1.00infobox
RAI1BioGPSn/a1.00infobox
RAI1Chr.Chromosome 17 (human)1.00infobox
RAI1Chr.Chromosome 11 (mouse)1.00infobox
RAI1DatabasesNCBI: entry; OMA: entry1.00infobox
RAI1End17,811,453 bp1.00infobox
RAI1End60,199,197 bp1.00infobox
RAI1EnsemblENSG000001085571.00infobox

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