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RAI1: Standards & Overview

Retinoic acid-induced protein 1 is a transcription factor that in humans is encoded by the RAI1 gene. Mutations or copy number alterations affecting this gene are associated with neurodevelopmental disorders. Deletions of RAI1 are a primary cause of Smith–Magenis syndrome, whereas duplications of the gene are associated with Potocki–Lupski syndrome.

Language: English [EN]
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RAI1 topic overview

The analysis highlights Standards and Overview as prominent areas in the source structure around RAI1.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
79
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
RAI1, SMCR, SMS, retinoic acid induced 1
Band
17p11.2 · 11|11 B1.3-B2
Bgee
retinal pigment epithelium · nipple · palpebral conjunctiva · urethra · pylorus
BioGPS
n/a
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RAI1 connects Entity context

The extracted context around RAI1 shows recurring relationship patterns in the source. For example, RAI1 → anterior amygdaloid area, Brodmann area 23, cardia, dorsomedial hypothalamic nucleus, habenula, human penis, lateral hypothalamus, lateral septal nucleus, mammillary body, nipple, olfactory tubercle, palpebral conjunctiva, parietal lobe, pylorus, retinal pigment epithelium, Rostral migratory stream, subiculum, tibia, urethra, ventromedial nucleus Another extracted example is RAI1 → circadian regulation of gene expression, cytoplasm, DNA-binding transcription factor activity, metal ion binding, mitochondrion, negative regulation of multicellular organism growth, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, regulation of transcription by RNA polymerase II, rhythmic process, skeletal system development. Use these groups to spot repeated connection types before inspecting the individual relationships.

RAI1

Top relations

Bgee · 20
RAI1 → anterior amygdaloid area, Brodmann area 23, cardia, dorsomedial hypothalamic nucleus, habenula, human penis, lateral hypothalamus, lateral septal nucleus, mammillary body, nipple, olfactory tubercle, palpebral conjunctiva, parietal lobe, pylorus, retinal pigment epithelium, Rostral migratory stream, subiculum, tibia, urethra, ventromedial nucleus
RNA expression pattern · 20
RAI1 → anterior amygdaloid area, Brodmann area 23, cardia, dorsomedial hypothalamic nucleus, habenula, human penis, lateral hypothalamus, lateral septal nucleus, mammillary body, nipple, olfactory tubercle, palpebral conjunctiva, parietal lobe, pylorus, retinal pigment epithelium, Rostral migratory stream, subiculum, tibia, urethra, ventromedial nucleus
Gene ontology · 14
RAI1 → circadian regulation of gene expression, cytoplasm, DNA-binding transcription factor activity, metal ion binding, mitochondrion, negative regulation of multicellular organism growth, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, regulation of transcription by RNA polymerase II, rhythmic process, skeletal system development
related to External links · 5
RAI1 → GeneReviews/NIH/NCBI/UW, Medicine Medical Subject Headings, MeSH, National Library, Smith-Magenis SyndromeRAI1
Band · 2
RAI1 → 11|11 B1.3-B2, 17p11.2
Chr. · 2
RAI1 → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
RAI1 → 17,811,453 bp, 60,199,197 bp
Aliases · 1
RAI1 → RAI1, SMCR, SMS, retinoic acid induced 1
BioGPS · 1
RAI1 → n/a
Databases · 1
RAI1 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp human chr band chromosome 17 retinoic protein location associated mouse transcription factor external syndrome 811 453 end 11

RAI1 relationships Subject–Predicate–Object triples

TTTA extracted 79 structured relationships around RAI1. Examples in this analysis include RAI1 → Aliases → RAI1, SMCR, SMS, retinoic acid induced 1 and RAI1 → Band → 17p11.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RAI1AliasesRAI1, SMCR, SMS, retinoic acid induced 11.00infobox
RAI1Band17p11.21.00infobox
RAI1Band11|11 B1.3-B21.00infobox
RAI1Bgeeretinal pigment epithelium1.00infobox
RAI1Bgeenipple1.00infobox
RAI1Bgeepalpebral conjunctiva1.00infobox
RAI1Bgeeurethra1.00infobox
RAI1Bgeepylorus1.00infobox
RAI1Bgeetibia1.00infobox
RAI1BgeeBrodmann area 231.00infobox
RAI1Bgeecardia1.00infobox
RAI1Bgeehuman penis1.00infobox
RAI1Bgeeparietal lobe1.00infobox
RAI1Bgeelateral septal nucleus1.00infobox
RAI1Bgeehabenula1.00infobox
RAI1Bgeeanterior amygdaloid area1.00infobox
RAI1Bgeeolfactory tubercle1.00infobox
RAI1Bgeeventromedial nucleus1.00infobox
RAI1Bgeesubiculum1.00infobox
RAI1Bgeedorsomedial hypothalamic nucleus1.00infobox
RAI1BgeeRostral migratory stream1.00infobox
RAI1Bgeelateral hypothalamus1.00infobox
RAI1Bgeemammillary body1.00infobox
RAI1BioGPSn/a1.00infobox
RAI1Chr.Chromosome 17 (human)1.00infobox
RAI1Chr.Chromosome 11 (mouse)1.00infobox
RAI1DatabasesNCBI: entry; OMA: entry1.00infobox
RAI1End17,811,453 bp1.00infobox
RAI1End60,199,197 bp1.00infobox
RAI1EnsemblENSG000001085571.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around RAI1 bring nearby vocabulary together. In this analysis, examples include Retinoic, Gene and Acid. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Rai1
    • Location
    • Retinoic
    • Chromosome
    • Human
    • Bp
    • Chr
    • Acid
    • Associated
    • B1
    • End
    • Mouse
  • transcription factor
    • Factor
    • Protein
    • Transcription
    • Retinoic
    • Acid-induced
    • Encoded
    • Entry
    • Humans
    • Ncbi
    • Rai1
    • Acid
    • B1
  • RAI1
    • Retinoic
    • Gene
    • Acid
    • Syndrome
    • Transcription
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Cause
    • Deletions
  • rai1
    • Retinoic
    • Gene
    • Acid
    • Syndrome
    • Transcription
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Cause
    • Deletions
  • copy number
    • Affecting
    • Alterations
    • Copy
    • Disorders
    • Mutations
    • Neurodevelopmental
    • Number
    • Associated
    • Gene
  • neurodevelopmental
    • Number
  • smith–magenis syndrome
    • Transcription
  • potocki–lupski syndrome
    • Transcription

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the RAI1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

RAI1

Nodes8
Edges7
Triples79
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around RAI1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RAI1 · EN edition · Analysis: TopicsToTalkAbout

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