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RAG1: Applications, Use in phylogenetics & Function

Recombination activating gene 1 also known as RAG-1 is a protein that in humans is encoded by the RAG1 gene.

Language: English [EN]
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RAG1 topic overview

The analysis highlights Applications, Use in phylogenetics and Function as prominent areas in the source structure around RAG1.

Related topics
22
Source areas
4
Connected nodes
26
Extracted relationships
117
Concept neighborhoods
13
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Use in phylogenetics · 8 topics
Function · 7 topics
Clinical significance · 4 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27
Aliases
RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1
Band
11p12 · 2 E2|2 53.88 cM
Bgee
thymus · buccal mucosa cell · testicle · bone marrow · spleen
BioGPS
n/a
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Use in phylogenetics

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How RAG1 connects Entity context

The extracted context around RAG1 shows recurring relationship patterns in the source. For example, RAG1 → adaptive immune response, B cell differentiation, catalytic activity, chromatin organization, DNA binding, DNA recombinase complex, DNA recombination, double-stranded DNA endodeoxyribonuclease activity, endodeoxyribonuclease complex, endonuclease activity, histone binding, histone monoubiquitination, hydrolase activity, identical protein binding, immune response, metabolism, metal ion binding, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of T cell apoptotic process, negative regulation of thymocyte apoptotic process Another extracted example is RAG1 → apex of heart, body of femur, bone marrow, bone marrow cell, buccal mucosa cell, granulocyte, inner cell mass, lens, right adrenal cortex, sexually immature organism, spleen, sternocleidomastoid muscle, stromal cell of endometrium, tendon of biceps brachii, testicle, thymus, tibiofemoral joint, trachea. Use these groups to spot repeated connection types before inspecting the individual relationships.

RAG1

Top relations

Gene ontology · 41
RAG1 → adaptive immune response, B cell differentiation, catalytic activity, chromatin organization, DNA binding, DNA recombinase complex, DNA recombination, double-stranded DNA endodeoxyribonuclease activity, endodeoxyribonuclease complex, endonuclease activity, histone binding, histone monoubiquitination, hydrolase activity, identical protein binding, immune response, metabolism, metal ion binding, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of T cell apoptotic process, negative regulation of thymocyte apoptotic process
Bgee · 18
RAG1 → apex of heart, body of femur, bone marrow, bone marrow cell, buccal mucosa cell, granulocyte, inner cell mass, lens, right adrenal cortex, sexually immature organism, spleen, sternocleidomastoid muscle, stromal cell of endometrium, tendon of biceps brachii, testicle, thymus, tibiofemoral joint, trachea
RNA expression pattern · 18
RAG1 → apex of heart, body of femur, bone marrow, bone marrow cell, buccal mucosa cell, granulocyte, inner cell mass, lens, right adrenal cortex, sexually immature organism, spleen, sternocleidomastoid muscle, stromal cell of endometrium, tendon of biceps brachii, testicle, thymus, tibiofemoral joint, trachea
related to Clinical significance · 12
RAG1 → Because, CID-G/A, Complete, However, Hypomorphic RAG, Idiopathic CD4, In, Omenn, RAG, RAG1/2, RAG2, The
related to Use in phylogenetics · 6
RAG1 → Although, DNA, For, In, NPCL, That
Band · 2
RAG1 → 11p12, 2 E2|2 53.88 cM
Chr. · 2
RAG1 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
RAG1 → 101,479,846 bp, 36,593,156 bp
2.3.2.27 · 1
RAG1 → ↗
Aliases · 1
RAG1 → RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

recombination bp gene chr human band activity phylogenetic humans chromosome 11 dna rag-1 used variants encoded protein mouse location sequences

RAG1 relationships Subject–Predicate–Object triples

TTTA extracted 117 structured relationships around RAG1. Examples in this analysis include RAG1 → 2.3.2.27 → ↗ and RAG1 → Aliases → RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
RAG12.3.2.271.00infobox
RAG1AliasesRAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 11.00infobox
RAG1Band11p121.00infobox
RAG1Band2 E2|2 53.88 cM1.00infobox
RAG1Bgeethymus1.00infobox
RAG1Bgeebuccal mucosa cell1.00infobox
RAG1Bgeetesticle1.00infobox
RAG1Bgeebone marrow1.00infobox
RAG1Bgeespleen1.00infobox
RAG1Bgeeapex of heart1.00infobox
RAG1Bgeetendon of biceps brachii1.00infobox
RAG1Bgeestromal cell of endometrium1.00infobox
RAG1Bgeebone marrow cell1.00infobox
RAG1Bgeeright adrenal cortex1.00infobox
RAG1Bgeetibiofemoral joint1.00infobox
RAG1Bgeebody of femur1.00infobox
RAG1Bgeegranulocyte1.00infobox
RAG1Bgeesternocleidomastoid muscle1.00infobox
RAG1Bgeeinner cell mass1.00infobox
RAG1Bgeesexually immature organism1.00infobox
RAG1Bgeetrachea1.00infobox
RAG1Bgeelens1.00infobox
RAG1BioGPSn/a1.00infobox
RAG1Chr.Chromosome 11 (human)1.00infobox
RAG1Chr.Chromosome 2 (mouse)1.00infobox
RAG1DatabasesNCBI: entry; OMA: entry1.00infobox
RAG1End36,593,156 bp1.00infobox
RAG1End101,479,846 bp1.00infobox
RAG1EnsemblENSG000001663491.00infobox
RAG1Entrez58961.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around RAG1 bring nearby vocabulary together. In this analysis, examples include Used, Phylogenetic and Recombination. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • RAG1
    • Used
    • Phylogenetic
    • Recombination
    • Taxa
    • Activity
    • Function
    • Rag2
    • Disease
    • Immune
    • Location
    • Mouse
    • Chromosome
  • rag1
    • Used
    • Phylogenetic
    • Recombination
    • Taxa
    • Activity
    • Function
    • Rag2
    • Disease
    • Immune
    • Location
    • Mouse
    • Chromosome
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • E2
    • End
    • Function
    • Protein
    • Encoded
    • Mouse
    • Recombination
  • rag-1/2 complex
    • Recombination
    • Dna
    • Activity
    • E2
    • End
    • Function
    • Genes
    • Involved
    • Protein
    • Encoded
    • Immune
    • Location
  • protein
    • Encoded
    • E2
    • End
    • Function
    • Involved
    • Recombination
    • Complex
    • Immune
    • Location
    • Mouse
    • Band
    • Chromosome
  • function
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Gene
    • Activity
    • E2
    • End
    • Involved
    • Protein
    • Recombination
  • recombination signal sequences
    • Taxa
    • Used
    • Deficiency
    • Rag
    • Sequences
    • Variants
  • v(d)j recombination
    • Deficiency
    • Rag
    • Sequences
    • Variants

Connections between topic areas Semantic bridges

For RAG1, one of the stronger structural bridges in this analysis connects RAG1 with Use in phylogenetics. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
RAG1Use in phylogenetics · splits 18 ⟂ 9
RAG1Function · splits 19 ⟂ 8
RAG1Clinical significance · splits 22 ⟂ 5
RAG1Overview · splits 23 ⟂ 4

Map overview Semantic statistics

RAG1

Nodes27
Edges26
Triples117
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around RAG1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Use in phylogenetics & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — RAG1 · EN edition · Analysis: TopicsToTalkAbout

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