RAG1

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Explore the main themes, entities and connections around RAG1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Use in phylogenetics

Phylogenetic Phylogenetic trees Species Taxa Fish

8 related topics

Function

Antibody T-cell receptor V(D)J recombination RAG-1/2 complex Recombination signal sequences

7 related topics

Clinical significance

T cell B cell Omenn syndrome Autosomal recessive

4 related topics

Overview

Protein Gene RAG2

3 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.3.2.27: ↗
Aliases: RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1
Band: 11p12 · 2 E2|2 53.88 cM
Bgee: thymus · buccal mucosa cell · testicle · bone marrow · spleen
BioGPS: n/a
Chr.: Chromosome 11 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Function

Antibody
T-cell receptor
V(D)J recombination
RAG-1/2 complex Recombination-activating gene
Recombination signal sequences
Heavy Immunoglobulin heavy chain
Light chains Immunoglobulin light chain

Clinical significance

Use in phylogenetics

Phylogenetic Phylogenetics
Phylogenetic trees Phylogenetic tree
Species
Taxa Taxon
Fish
Reptiles Reptile
Mitochondrial sequences Mitochondrial DNA
Mito-nuclear discordance Cytonuclear discordance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes27

Edges26

Triples117

Avg. degree1.93

Density0.074074

Components1

How this topic connects Entity context

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RAG1

Top relations

Gene ontology · 41

RAG1 → adaptive immune response, B cell differentiation, catalytic activity, chromatin organization, DNA binding, DNA recombinase complex, DNA recombination, double-stranded DNA endodeoxyribonuclease activity, endodeoxyribonuclease complex, endonuclease activity, histone binding, histone monoubiquitination, hydrolase activity, identical protein binding, immune response, metabolism, metal ion binding, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of T cell apoptotic process, negative regulation of thymocyte apoptotic process

Bgee · 18

RAG1 → apex of heart, body of femur, bone marrow, bone marrow cell, buccal mucosa cell, granulocyte, inner cell mass, lens, right adrenal cortex, sexually immature organism, spleen, sternocleidomastoid muscle, stromal cell of endometrium, tendon of biceps brachii, testicle, thymus, tibiofemoral joint, trachea

RNA expression pattern · 18

related to Clinical significance · 12

RAG1 → Because, CID-G/A, Complete, However, Hypomorphic RAG, Idiopathic CD4, In, Omenn, RAG, RAG1/2, RAG2, The

related to Use in phylogenetics · 6

RAG1 → Although, DNA, For, In, NPCL, That

Band · 2

RAG1 → 11p12, 2 E2|2 53.88 cM

Chr. · 2

RAG1 → Chromosome 11 (human), Chromosome 2 (mouse)

End · 2

RAG1 → 101,479,846 bp, 36,593,156 bp

2.3.2.27 · 1

RAG1 → ↗

Aliases · 1

RAG1 → RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

recombination bp gene chr human band activity phylogenetic humans chromosome 11 dna rag-1 used variants encoded protein mouse location sequences

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
RAG1	2.3.2.27	↗	1.00	infobox
RAG1	Aliases	RAG1, RAG-1, RNF74, recombination activating gene 1, recombination activating 1	1.00	infobox
RAG1	Band	11p12	1.00	infobox
RAG1	Band	2 E2\|2 53.88 cM	1.00	infobox
RAG1	Bgee	thymus	1.00	infobox
RAG1	Bgee	buccal mucosa cell	1.00	infobox
RAG1	Bgee	testicle	1.00	infobox
RAG1	Bgee	bone marrow	1.00	infobox
RAG1	Bgee	spleen	1.00	infobox
RAG1	Bgee	apex of heart	1.00	infobox
RAG1	Bgee	tendon of biceps brachii	1.00	infobox
RAG1	Bgee	stromal cell of endometrium	1.00	infobox
RAG1	Bgee	bone marrow cell	1.00	infobox
RAG1	Bgee	right adrenal cortex	1.00	infobox
RAG1	Bgee	tibiofemoral joint	1.00	infobox
RAG1	Bgee	body of femur	1.00	infobox
RAG1	Bgee	granulocyte	1.00	infobox
RAG1	Bgee	sternocleidomastoid muscle	1.00	infobox
RAG1	Bgee	inner cell mass	1.00	infobox
RAG1	Bgee	sexually immature organism	1.00	infobox
RAG1	Bgee	trachea	1.00	infobox
RAG1	Bgee	lens	1.00	infobox
RAG1	BioGPS	n/a	1.00	infobox
RAG1	Chr.	Chromosome 11 (human)	1.00	infobox
RAG1	Chr.	Chromosome 2 (mouse)	1.00	infobox
RAG1	Databases	NCBI: entry; OMA: entry	1.00	infobox
RAG1	End	36,593,156 bp	1.00	infobox
RAG1	End	101,479,846 bp	1.00	infobox
RAG1	Ensembl	ENSG00000166349	1.00	infobox
RAG1	Entrez	5896	1.00	infobox

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