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PUS1: Overview, Related Topics & Entities

tRNA pseudouridine synthase A is an enzyme that in humans is encoded by the PUS1 gene.

Language: English [EN]
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PUS1 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around PUS1.

Related topics
10
Source areas
1
Connected nodes
11
Extracted relationships
81
Concept neighborhoods
11
Bridge connections
11

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 10 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

5.4.99.12
Aliases
PUS1, MLASA1, pseudouridylate synthase 1, pseudouridine synthase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IQM, 4ITS, 4J37, 4NZ6, 4NZ7
Band
12q24.33 · 5|5 F
Bgee
granulocyte · mucosa of transverse colon · right lobe of liver · gonad · spleen
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How PUS1 connects Entity context

The extracted context around PUS1 shows recurring relationship patterns in the source. For example, PUS1 → body of pancreas, embryo, endothelial cell of lymphatic vessel, epiblast, gonad, granulocyte, left adrenal cortex, left adrenal gland, lip, mucosa of transverse colon, primitive streak, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, seminal vesicula, spleen, ventricular zone, yolk sac Another extracted example is PUS1 → isomerase activity, mitochondrial matrix, mitochondrial tRNA pseudouridine synthesis, mitochondrion, mRNA pseudouridine synthesis, nucleus, pseudouridine synthase activity, pseudouridine synthesis, pseudouridylate synthase activity, RNA binding, RNA modification, steroid receptor RNA activator RNA binding, tRNA binding, tRNA processing, tRNA pseudouridine synthase activity, tRNA pseudouridine synthesis. Use these groups to spot repeated connection types before inspecting the individual relationships.

PUS1

Top relations

Bgee · 20
PUS1 → body of pancreas, embryo, endothelial cell of lymphatic vessel, epiblast, gonad, granulocyte, left adrenal cortex, left adrenal gland, lip, mucosa of transverse colon, primitive streak, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, seminal vesicula, spleen, ventricular zone, yolk sac
RNA expression pattern · 20
PUS1 → body of pancreas, embryo, endothelial cell of lymphatic vessel, epiblast, gonad, granulocyte, left adrenal cortex, left adrenal gland, lip, mucosa of transverse colon, primitive streak, proximal tubule, right adrenal cortex, right adrenal gland, right kidney, right lobe of liver, seminal vesicula, spleen, ventricular zone, yolk sac
Gene ontology · 16
PUS1 → isomerase activity, mitochondrial matrix, mitochondrial tRNA pseudouridine synthesis, mitochondrion, mRNA pseudouridine synthesis, nucleus, pseudouridine synthase activity, pseudouridine synthesis, pseudouridylate synthase activity, RNA binding, RNA modification, steroid receptor RNA activator RNA binding, tRNA binding, tRNA processing, tRNA pseudouridine synthase activity, tRNA pseudouridine synthesis
Band · 2
PUS1 → 12q24.33, 5|5 F
Chr. · 2
PUS1 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
PUS1 → 110,928,525 bp, 131,945,896 bp
5.4.99.12 · 1
PUS1 → ↗
Aliases · 1
PUS1 → PUS1, MLASA1, pseudouridylate synthase 1, pseudouridine synthase 1
Available structures · 1
PUS1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IQM, 4ITS, 4J37, 4NZ6, 4NZ7
BioGPS · 1
PUS1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

pseudouridine gene bp chr human band synthase 12 chromosome trna mitochondrial location enzyme rna omim mouse pseudouridylate search activity 945

PUS1 relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around PUS1. Examples in this analysis include PUS1 → 5.4.99.12 → ↗ and PUS1 → Aliases → PUS1, MLASA1, pseudouridylate synthase 1, pseudouridine synthase 1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
PUS15.4.99.121.00infobox
PUS1AliasesPUS1, MLASA1, pseudouridylate synthase 1, pseudouridine synthase 11.00infobox
PUS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4IQM, 4ITS, 4J37, 4NZ6, 4NZ71.00infobox
PUS1Band12q24.331.00infobox
PUS1Band5|5 F1.00infobox
PUS1Bgeegranulocyte1.00infobox
PUS1Bgeemucosa of transverse colon1.00infobox
PUS1Bgeeright lobe of liver1.00infobox
PUS1Bgeegonad1.00infobox
PUS1Bgeespleen1.00infobox
PUS1Bgeeright adrenal gland1.00infobox
PUS1Bgeeleft adrenal gland1.00infobox
PUS1Bgeebody of pancreas1.00infobox
PUS1Bgeeleft adrenal cortex1.00infobox
PUS1Bgeeright adrenal cortex1.00infobox
PUS1Bgeeyolk sac1.00infobox
PUS1Bgeeprimitive streak1.00infobox
PUS1Bgeeright kidney1.00infobox
PUS1Bgeeproximal tubule1.00infobox
PUS1Bgeeendothelial cell of lymphatic vessel1.00infobox
PUS1Bgeeseminal vesicula1.00infobox
PUS1Bgeeepiblast1.00infobox
PUS1Bgeeembryo1.00infobox
PUS1Bgeeventricular zone1.00infobox
PUS1Bgeelip1.00infobox
PUS1BioGPSMore reference expression data1.00infobox
PUS1Chr.Chromosome 12 (human)1.00infobox
PUS1Chr.Chromosome 5 (mouse)1.00infobox
PUS1DatabasesNCBI: entry; OMA: entry1.00infobox
PUS1End131,945,896 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around PUS1 bring nearby vocabulary together. In this analysis, examples include Gene, Synthase and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • pseudouridine
    • Pus1
    • Synthase
    • Gene
    • Activity
    • Enzyme
    • Omim
    • Pseudouridylate
    • Rna
    • Search
    • Trna
    • Location
    • Chromosome
  • PUS1
    • Gene
    • Synthase
    • Activity
    • Mitochondrial
    • Pseudouridylate
    • Rna
    • Search
    • Trna
    • Location
    • Chromosome
    • Human
    • Bp
  • pus1
    • Gene
    • Synthase
    • Activity
    • Mitochondrial
    • Pseudouridylate
    • Rna
    • Search
    • Trna
    • Location
    • Chromosome
    • Human
    • Bp
  • gene
    • Pus1
    • Location
    • Synthase
    • Chromosome
    • Human
    • Bp
    • Chr
    • Pseudouridine
    • Activity
    • End
    • Mitochondrial
    • Mouse
  • enzyme
    • Synthase
    • Encoded
    • Humans
    • Gene
    • Pseudouridine
    • Pus1
    • Activity
    • Omim
    • Pseudouridylate
    • Search
    • Trna
    • Location
  • mitochondrial myopathy
    • Pus1
    • Activity
    • End
    • Mouse
    • Pseudouridylate
    • Rna
    • Search
    • Trna
    • Location
    • Synthase
    • Band
    • Chromosome
  • rna
    • Uridine
    • Activity
    • End
    • Mitochondrial
    • Mouse
    • Pseudouridylate
    • Search
    • Trna
    • Location
    • Synthase
    • Band
    • Chromosome
  • trnas
    • Assist
    • Functional
    • May
    • Peptidyl
    • Role
    • Rrnas
    • Transfer
    • Omim
    • Pseudouridine

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the PUS1 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

PUS1

Nodes12
Edges11
Triples81
Avg. degree1.83
Density0.166667
Components1

Source & methodology

TTTA analyzes the structure around PUS1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — PUS1 · EN edition · Analysis: TopicsToTalkAbout

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