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Pridopidine

Pridopidine (developmental code name PL-101) is an orally administrated small molecule investigational drug. Pridopidine is a selective and potent sigma-1 receptor agonist. It is being developed by Prilenia Therapeutics and is currently in late-stage clinical development for Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS).

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3D model (JSmol)
Interactive image
ATC code
N07XX26 (WHO)
CAS Number
346688-38-8
ChEMBL
ChEMBL596802
ChemSpider
7971505
CompTox Dashboard (EPA)
DTXSID90188225

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Overview

Mechanism of action

Chemistry

Potential indications

Society and culture

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Map overview Semantic statistics

Pridopidine

Nodes23
Edges22
Triples42
Avg. degree1.91
Density0.086957
Components1

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Pridopidine

Top relations

related to Huntington's disease · 13
Pridopidine → Adult-onset HD, CAG, Following, For, HD, However, Huntingtin, Huntington's, Modified Motor Score, RCTs, Scale Total Motor Score, The, Unified Huntington's Disease Rating
related to Mechanism of action · 11
Pridopidine → AD, ALS, Alzheimer's, Glaucoma, HD, MAM, Parkinson's, PD, S1R, Selective, The S1R
related to Analogues · 3
Pridopidine → Analogues, OSU-6162, PPP
3D model (JSmol) · 1
Pridopidine → Interactive image
ATC code · 1
Pridopidine → N07XX26 (WHO)
CAS Number · 1
Pridopidine → 346688-38-8
ChEMBL · 1
Pridopidine → ChEMBL596802
ChemSpider · 1
Pridopidine → 7971505
CompTox Dashboard (EPA) · 1
Pridopidine → DTXSID90188225
Drug class · 1
Pridopidine → Sigma σ1 receptor agonist

Important terminology Word statistics

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Important terminology

disease hd s1r motor huntington's als drug receptor neurodegenerative selective amyotrophic lateral sclerosis progressive symptoms patients trial agonist code name

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Pridopidine3D model (JSmol)Interactive image1.00infobox
PridopidineATC codeN07XX26 (WHO)1.00infobox
PridopidineCAS Number346688-38-81.00infobox
PridopidineChEMBLChEMBL5968021.00infobox
PridopidineChemSpider79715051.00infobox
PridopidineCompTox Dashboard (EPA)DTXSID901882251.00infobox
PridopidineDrug classSigma σ1 receptor agonist1.00infobox
PridopidineDrugBankDB053711.00infobox
PridopidineECHA InfoCard100.240.9981.00infobox
PridopidineFormulaC15H23NO2S1.00infobox
PridopidineKEGGD099531.00infobox
PridopidineMolar mass281.41 g·mol−11.00infobox
PridopidinePubChem CID97957391.00infobox
PridopidineUNIIHD4TW8S2VK1.00infobox
Pridopidineis aselective and potent sigma-1 receptor agonist0.90text

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