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Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide)). The word poloxamer was coined by BASF inventor, Irving Schmolka, who received the patent for these materials in 1973. Poloxamers are also known by the…
The analysis highlights Applications, Uses and Micellization and phase transitions as prominent areas in the source structure around Poloxamer.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Poloxamer shows recurring relationship patterns in the source. For example, Poloxamer → Above, An, At, Concentrated, PPO, The, This, Thus Another extracted example is Poloxamer → Among, Because, Bio, For, In, Kolliphor, There, They. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
poloxamers polyoxyethylene polyoxypropylene also temperature two cells shown copolymers pluronic hydrophobic polymers molecular water increase used polymer blocks different synperonic
TTTA extracted 52 structured relationships around Poloxamer. Examples in this analysis include the formation of highly ordered mesophases → instance of → other phenomena can occur and salts → instance of → This is due to the fact that hydrogen bonding between the polyoxyethylene and the water molecules breaks down at high temperature and polyoxyethylene becomes also insoluble in w…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| the formation of highly ordered mesophases | instance of | other phenomena can occur | 0.80 | text |
| salts | instance of | This is due to the fact that hydrogen bonding between the polyoxyethylene and the water molecules breaks down at high temperature and polyoxyethylene becomes also insoluble in w… | 0.80 | text |
| alcohols | instance of | This is due to the fact that hydrogen bonding between the polyoxyethylene and the water molecules breaks down at high temperature and polyoxyethylene becomes also insoluble in w… | 0.80 | text |
| Pluronic F-108 or Pluronic F-127 | instance of | certain poloxamers | 0.80 | text |
| are used as steric stabilizers to prevent coalescence and/or reduce aggregation | instance of | certain poloxamers | 0.80 | text |
| doxorubicin.Another effect of the polymers upon cancer cells is the inhibition of the production of ATP in multi-drug resistant | instance of | the MDR proteins are responsible for the efflux of drugs from the cells and hence increase the susceptibility of cancer cells to chemotherapeutic agents | 0.80 | text |
| P85 have been shown not only to be able to transport target genes to target cells | instance of | and abolish drug sequestering within cytoplasmic vesicles.On nuclear factor kappa BCertain poloxamers | 0.80 | text |
| but also to increase gene expression | instance of | and abolish drug sequestering within cytoplasmic vesicles.On nuclear factor kappa BCertain poloxamers | 0.80 | text |
| P85 have been shown not only to be able to transport target genes to target cells | instance of | On nuclear factor kappa BCertain poloxamers | 0.80 | text |
| but also to increase gene expression | instance of | On nuclear factor kappa BCertain poloxamers | 0.80 | text |
| Poloxamer | related to Biological effect | Work | 0.60 | section |
| Poloxamer | related to Biological effect | Kabanov | 0.60 | section |
The concept neighborhoods around Poloxamer bring nearby vocabulary together. In this analysis, examples include Content, Mass and Molecular. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Poloxamer, one of the stronger structural bridges in this analysis connects Poloxamer with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Poloxamer to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Uses & Micellization and phase transitions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Poloxamer · EN edition · Analysis: TopicsToTalkAbout