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Poloxamer

Poloxamers are nonionic triblock copolymers composed of a central hydrophobic chain of polyoxypropylene (poly(propylene oxide)) flanked by two hydrophilic chains of polyoxyethylene (poly(ethylene oxide)). The word poloxamer was coined by BASF inventor, Irving Schmolka, who received the patent for these materials in 1973. Poloxamers are also known by the…

Applications, Uses & Micellization and phase transitions

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Overview

Micellization and phase transitions

Uses

Biological effect

Advanced semantic analysis

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Map overview Semantic statistics

Poloxamer

Nodes32
Edges31
Triples52
Avg. degree1.94
Density0.0625
Components1

How this topic connects Entity context

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Poloxamer

Top relations

related to Micellization and phase transitions · 8
Poloxamer → Above, An, At, Concentrated, PPO, The, This, Thus
related to Uses · 8
Poloxamer → Among, Because, Bio, For, In, Kolliphor, There, They
related to On multi drug resistant cancer cells · 6
Poloxamer → Another, ATP, IV, MDR, Poloxamers, The
related to Further reading · 5
Poloxamer → Gonjari ID, Hosmani AH, Karmarkar AB, Pharmacy Student Articles, Poloxamers
related to Potential degradation by sonication · 5
Poloxamer → Moreover, MWNTs, Pluronic F-127, Pluronic F-68, Wang
related to On nuclear factor kappa B · 4
Poloxamer → Certain, L61, NF, P85
related to Biological effect · 3
Poloxamer → Kabanov, The, Work
related to External links · 3
Poloxamer → Healing Injury, Revolutionary Approach, Video Poloxamer-188

Important terminology Word statistics

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Important terminology

poloxamers polyoxyethylene polyoxypropylene also temperature two cells shown copolymers pluronic hydrophobic polymers molecular water increase used polymer blocks different synperonic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
the formation of highly ordered mesophasesinstance ofother phenomena can occur0.80text
saltsinstance ofThis is due to the fact that hydrogen bonding between the polyoxyethylene and the water molecules breaks down at high temperature and polyoxyethylene becomes also insoluble in w…0.80text
alcoholsinstance ofThis is due to the fact that hydrogen bonding between the polyoxyethylene and the water molecules breaks down at high temperature and polyoxyethylene becomes also insoluble in w…0.80text
Pluronic F-108 or Pluronic F-127instance ofcertain poloxamers0.80text
are used as steric stabilizers to prevent coalescence and/or reduce aggregationinstance ofcertain poloxamers0.80text
doxorubicin.Another effect of the polymers upon cancer cells is the inhibition of the production of ATP in multi-drug resistantinstance ofthe MDR proteins are responsible for the efflux of drugs from the cells and hence increase the susceptibility of cancer cells to chemotherapeutic agents0.80text
P85 have been shown not only to be able to transport target genes to target cellsinstance ofand abolish drug sequestering within cytoplasmic vesicles.On nuclear factor kappa BCertain poloxamers0.80text
but also to increase gene expressioninstance ofand abolish drug sequestering within cytoplasmic vesicles.On nuclear factor kappa BCertain poloxamers0.80text
P85 have been shown not only to be able to transport target genes to target cellsinstance ofOn nuclear factor kappa BCertain poloxamers0.80text
but also to increase gene expressioninstance ofOn nuclear factor kappa BCertain poloxamers0.80text
Poloxamerrelated to Biological effectWork0.60section
Poloxamerrelated to Biological effectKabanov0.60section

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