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PKPD modeling (pharmacokinetic pharmacodynamic modeling) (alternatively abbreviated as PK/PD or PK-PD modeling) is a technique that combines the two classical pharmacologic disciplines of pharmacokinetics and pharmacodynamics. It integrates a pharmacokinetic and a pharmacodynamic model component into one set of mathematical expressions that allows the…
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pkpd modeling drug administration exposure-response pharmacokinetic pharmacodynamic model time effect response models exist relationships pharmacologic pharmacokinetics pharmacodynamics pharmacometrics alternatively abbreviated
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| linear model | instance of | PKPD relationships can be described by simple equations | 0.80 | text |
| Emax model or sigmoid Emax model | instance of | PKPD relationships can be described by simple equations | 0.80 | text |
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