PHOX2B

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Immunohistochemistry

Autonomic nervous system Neuroblasts Neural crest cells Immunohistochemical staining Neuroblastoma

5 related topics

Pathology

Congenital central hypoventilation syndrome Hirschsprung's disease Enteric nervous system ROHHAD Sympathetic ganglia

5 related topics

Overview

Protein Gene Chromosome 4 Homeodomain

4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: PHOX2B, NBLST2, NBPhox, PMX2B, paired like homeobox 2b, CCHS
Band: 4p13 · 5 C3.1|5 35.95 cM
Bgee: muscle layer of sigmoid colon · buccal mucosa cell · dorsal motor nucleus of vagus nerve · inferior olivary nucleus · rectum
BioGPS: n/a
Chr.: Chromosome 4 (human) · Chromosome 5 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Protein
Gene
Chromosome 4 Chromosome 4 (human)
Homeodomain

Immunohistochemistry

Autonomic nervous system
Neuroblasts Neuroblast
Neural crest cells Neural crest
Immunohistochemical staining Immunohistochemistry
Neuroblastoma

Pathology

Advanced semantic analysis

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Map overview Semantic statistics

Nodes18

Edges17

Triples130

Avg. degree1.89

Density0.111111

Components1

How this topic connects Entity context

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PHOX2B

Top relations

Gene ontology · 44

PHOX2B → autonomic nervous system development, brainstem development, cell development, cell differentiation in hindbrain, cellular response to BMP stimulus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, dopaminergic neuron differentiation, efferent axon development in a lateral line nerve, enteric nervous system development, glial cell differentiation, hindbrain tangential cell migration, inner ear development, medullary reticular formation development, multicellular organism development, negative regulation of cell population proliferation, negative regulation of neuron differentiation, nervous system development, neural crest cell migration involved in autonomic nervous system development

Bgee · 20

PHOX2B → adrenal gland, appendix, buccal mucosa cell, dorsal motor nucleus of vagus nerve, duodenum, enteric nervous system, external carotid artery, facial motor nucleus, female urethra, inferior olivary nucleus, internal carotid artery, male urethra, medial vestibular nucleus, migratory enteric neural crest cell, muscle layer of sigmoid colon, pelvic ganglion, rectum, right adrenal gland, small intestine, transverse colon

RNA expression pattern · 20

related to Research · 9

PHOX2B → CCHS, Congenitial Central Hypoventilation Syndrome, Keep Me Breathing, Organisations, September, The CCHS Network, These, UK, USA

related to Pathology · 7

PHOX2B → An, Exon, Hirschsprung's, In, Mutations, ROHHAD, There

related to External links · 5

PHOX2B → Congenital Central Hypoventilation SyndromePhox2b, GeneReviews/NCBI/NIH/UW, Medicine Medical Subject Headings, MeSH, National Library

related to Immunohistochemistry · 4

PHOX2B → Essential, Its, Neuroblasts, The

Band · 2

PHOX2B → 4p13, 5 C3.1|5 35.95 cM

Chr. · 2

PHOX2B → Chromosome 4 (human), Chromosome 5 (mouse)

End · 2

PHOX2B → 41,748,725 bp, 67,256,644 bp

Important terminology Word statistics

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Important terminology

bp gene human chromosome also chr band nervous system differentiation neuroblastoma protein external transcription factor respiratory location central hypoventilation syndrome

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
PHOX2B	Aliases	PHOX2B, NBLST2, NBPhox, PMX2B, paired like homeobox 2b, CCHS	1.00	infobox
PHOX2B	Band	4p13	1.00	infobox
PHOX2B	Band	5 C3.1\|5 35.95 cM	1.00	infobox
PHOX2B	Bgee	muscle layer of sigmoid colon	1.00	infobox
PHOX2B	Bgee	buccal mucosa cell	1.00	infobox
PHOX2B	Bgee	dorsal motor nucleus of vagus nerve	1.00	infobox
PHOX2B	Bgee	inferior olivary nucleus	1.00	infobox
PHOX2B	Bgee	rectum	1.00	infobox
PHOX2B	Bgee	transverse colon	1.00	infobox
PHOX2B	Bgee	appendix	1.00	infobox
PHOX2B	Bgee	small intestine	1.00	infobox
PHOX2B	Bgee	right adrenal gland	1.00	infobox
PHOX2B	Bgee	duodenum	1.00	infobox
PHOX2B	Bgee	migratory enteric neural crest cell	1.00	infobox
PHOX2B	Bgee	external carotid artery	1.00	infobox
PHOX2B	Bgee	pelvic ganglion	1.00	infobox
PHOX2B	Bgee	enteric nervous system	1.00	infobox
PHOX2B	Bgee	internal carotid artery	1.00	infobox
PHOX2B	Bgee	adrenal gland	1.00	infobox
PHOX2B	Bgee	facial motor nucleus	1.00	infobox
PHOX2B	Bgee	female urethra	1.00	infobox
PHOX2B	Bgee	medial vestibular nucleus	1.00	infobox
PHOX2B	Bgee	male urethra	1.00	infobox
PHOX2B	BioGPS	n/a	1.00	infobox
PHOX2B	Chr.	Chromosome 4 (human)	1.00	infobox
PHOX2B	Chr.	Chromosome 5 (mouse)	1.00	infobox
PHOX2B	Databases	NCBI: entry; OMA: entry	1.00	infobox
PHOX2B	End	41,748,725 bp	1.00	infobox
PHOX2B	End	67,256,644 bp	1.00	infobox
PHOX2B	Ensembl	ENSG00000109132	1.00	infobox

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