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Paired-like homeobox 2b (PHOX2B), also known as neuroblastoma Phox (NBPhox), is a protein that in humans is encoded by the PHOX2B gene located on chromosome 4.
The analysis highlights Immunohistochemistry, Pathology and Overview as prominent areas in the source structure around PHOX2B.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A focused starting point derived from the topic graph, ranked independently of the source article order.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PHOX2B shows recurring relationship patterns in the source. For example, PHOX2B → autonomic nervous system development, brainstem development, cell development, cell differentiation in hindbrain, cellular response to BMP stimulus, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, RNA polymerase II-specific, dopaminergic neuron differentiation, efferent axon development in a lateral line nerve, enteric nervous system development, glial cell differentiation, hindbrain tangential cell migration, inner ear development, medullary reticular formation development, multicellular organism development, negative regulation of cell population proliferation, negative regulation of neuron differentiation, nervous system development, neural crest cell migration involved in autonomic nervous system development Another extracted example is PHOX2B → adrenal gland, appendix, buccal mucosa cell, dorsal motor nucleus of vagus nerve, duodenum, enteric nervous system, external carotid artery, facial motor nucleus, female urethra, inferior olivary nucleus, internal carotid artery, male urethra, medial vestibular nucleus, migratory enteric neural crest cell, muscle layer of sigmoid colon, pelvic ganglion, rectum, right adrenal gland, small intestine, transverse colon. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
bp gene human chromosome also chr band nervous system differentiation neuroblastoma protein external transcription factor respiratory location central hypoventilation syndrome
TTTA extracted 130 structured relationships around PHOX2B. Examples in this analysis include PHOX2B → Aliases → PHOX2B, NBLST2, NBPhox, PMX2B, paired like homeobox 2b, CCHS and PHOX2B → Band → 4p13. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PHOX2B | Aliases | PHOX2B, NBLST2, NBPhox, PMX2B, paired like homeobox 2b, CCHS | 1.00 | infobox |
| PHOX2B | Band | 4p13 | 1.00 | infobox |
| PHOX2B | Band | 5 C3.1|5 35.95 cM | 1.00 | infobox |
| PHOX2B | Bgee | muscle layer of sigmoid colon | 1.00 | infobox |
| PHOX2B | Bgee | buccal mucosa cell | 1.00 | infobox |
| PHOX2B | Bgee | dorsal motor nucleus of vagus nerve | 1.00 | infobox |
| PHOX2B | Bgee | inferior olivary nucleus | 1.00 | infobox |
| PHOX2B | Bgee | rectum | 1.00 | infobox |
| PHOX2B | Bgee | transverse colon | 1.00 | infobox |
| PHOX2B | Bgee | appendix | 1.00 | infobox |
| PHOX2B | Bgee | small intestine | 1.00 | infobox |
| PHOX2B | Bgee | right adrenal gland | 1.00 | infobox |
| PHOX2B | Bgee | duodenum | 1.00 | infobox |
| PHOX2B | Bgee | migratory enteric neural crest cell | 1.00 | infobox |
| PHOX2B | Bgee | external carotid artery | 1.00 | infobox |
| PHOX2B | Bgee | pelvic ganglion | 1.00 | infobox |
| PHOX2B | Bgee | enteric nervous system | 1.00 | infobox |
| PHOX2B | Bgee | internal carotid artery | 1.00 | infobox |
| PHOX2B | Bgee | adrenal gland | 1.00 | infobox |
| PHOX2B | Bgee | facial motor nucleus | 1.00 | infobox |
| PHOX2B | Bgee | female urethra | 1.00 | infobox |
| PHOX2B | Bgee | medial vestibular nucleus | 1.00 | infobox |
| PHOX2B | Bgee | male urethra | 1.00 | infobox |
| PHOX2B | BioGPS | n/a | 1.00 | infobox |
| PHOX2B | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| PHOX2B | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| PHOX2B | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PHOX2B | End | 41,748,725 bp | 1.00 | infobox |
| PHOX2B | End | 67,256,644 bp | 1.00 | infobox |
| PHOX2B | Ensembl | ENSG00000109132 | 1.00 | infobox |
The concept neighborhoods around PHOX2B bring nearby vocabulary together. In this analysis, examples include Crest, Neural and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PHOX2B, one of the stronger structural bridges in this analysis connects PHOX2B with Immunohistochemistry. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PHOX2B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Immunohistochemistry, Pathology & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PHOX2B · EN edition · Analysis: TopicsToTalkAbout