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Research this topic
Explore the main themes, entities and connections around PHF8. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Clinical significance
19 related topics
Function
2 related topics
Overview
2 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 1.14.11.65
- ↗
- Aliases
- PHF8, JHDM1F, MRXSSD, ZNF422, PHD finger protein 8, KDM7B
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4DO0, 3K3O, 2WWU, 3K3N, 3KV4,%%s2WWU, 3K3N, 3K3O, 3KV4, 4DO0
- Band
- Xp11.22 · X|X F3
- Bgee
- right testis · sural nerve · left testis · testicle · tendon of biceps brachii
- BioGPS
- n/a
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Function
Clinical significance
- X-linked intellectual disability
- OMIM Online Mendelian Inheritance in Man
- Intellectual disability
- Cleft lip
- Microcephaly
- Microdeletion
- Autism spectrum disorder
- Cleft lip and palate
- Dysmorphism
- Cleft lip/palate
- Nuclear localisation
- Oxygen
- Hypoxia Hypoxia (medical)
- Pregnancy
- Fetal
- Congenital abnormalities
- Maternal smoking Smoking and pregnancy
- Alcohol use Alcohol use disorder
- Hypertension
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.PHF8
Nodes27
Edges26
Triples121
Avg. degree1.93
Density0.074074
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
PHF8
Top relations
Gene ontology · 31
PHF8 → 2-oxoglutarate-dependent dioxygenase activity, brain development, cell cycle, chromatin binding, chromatin organization, dioxygenase activity, G1/S transition of mitotic cell cycle, histone demethylase activity, histone H3-K27 demethylation, histone H3-K36 demethylation, histone H3-K9 demethylation, histone H3-methyl-lysine-36 demethylase activity, histone H3-methyl-lysine-9 demethylase activity, histone H3-tri/di-methyl-lysine-27 demethylase activity, histone H4-K20 demethylation, histone H4-methyl-lysine-20 demethylase activity, iron ion binding, metal ion binding, methylated histone binding, negative regulation of ribosomal DNA heterochromatin assembly
Bgee · 20
PHF8 → Achilles tendon, blood, epithelium of colon, gonad, Gonadal ridge, granulocyte, left testis, medial ganglionic eminence, otic placode, otic vesicle, primary oocyte, right lobe of liver, right testis, right uterine tube, saccule, secondary oocyte, sural nerve, tendon of biceps brachii, testicle, zygote
RNA expression pattern · 20
PHF8 → Achilles tendon, blood, epithelium of colon, gonad, Gonadal ridge, granulocyte, left testis, medial ganglionic eminence, otic placode, otic vesicle, primary oocyte, right lobe of liver, right testis, right uterine tube, saccule, secondary oocyte, sural nerve, tendon of biceps brachii, testicle, zygote
related to Clinical significance · 15
PHF8 → FAM120C, Finnish, In, JmjC, Mutations, OMIM, Siderius, Siderius-Hamel, Siderius-type XLMR, The F279S, This, WNK3, X-linked, XLMR, Xp11
related to External links · 6
PHF8 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
related to Function · 3
PHF8 → EMT, SNAI1, ZEB1
Band · 2
PHF8 → Xp11.22, X|X F3
Chr. · 2
PHF8 → X chromosome (human), X chromosome (mouse)
End · 2
PHF8 → 150,416,855 bp, 54,048,958 bp
1.14.11.65 · 1
PHF8 → ↗
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
human bp gene chr band protein chromosome cleft lip activity location palate mouse phd finger function regulation external omim found
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PHF8 | 1.14.11.65 | ↗ | 1.00 | infobox |
| PHF8 | Aliases | PHF8, JHDM1F, MRXSSD, ZNF422, PHD finger protein 8, KDM7B | 1.00 | infobox |
| PHF8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4DO0, 3K3O, 2WWU, 3K3N, 3KV4,%%s2WWU, 3K3N, 3K3O, 3KV4, 4DO0 | 1.00 | infobox |
| PHF8 | Band | Xp11.22 | 1.00 | infobox |
| PHF8 | Band | X|X F3 | 1.00 | infobox |
| PHF8 | Bgee | right testis | 1.00 | infobox |
| PHF8 | Bgee | sural nerve | 1.00 | infobox |
| PHF8 | Bgee | left testis | 1.00 | infobox |
| PHF8 | Bgee | testicle | 1.00 | infobox |
| PHF8 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| PHF8 | Bgee | Achilles tendon | 1.00 | infobox |
| PHF8 | Bgee | epithelium of colon | 1.00 | infobox |
| PHF8 | Bgee | right lobe of liver | 1.00 | infobox |
| PHF8 | Bgee | gonad | 1.00 | infobox |
| PHF8 | Bgee | right uterine tube | 1.00 | infobox |
| PHF8 | Bgee | zygote | 1.00 | infobox |
| PHF8 | Bgee | primary oocyte | 1.00 | infobox |
| PHF8 | Bgee | otic vesicle | 1.00 | infobox |
| PHF8 | Bgee | saccule | 1.00 | infobox |
| PHF8 | Bgee | blood | 1.00 | infobox |
| PHF8 | Bgee | secondary oocyte | 1.00 | infobox |
| PHF8 | Bgee | otic placode | 1.00 | infobox |
| PHF8 | Bgee | Gonadal ridge | 1.00 | infobox |
| PHF8 | Bgee | granulocyte | 1.00 | infobox |
| PHF8 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| PHF8 | BioGPS | n/a | 1.00 | infobox |
| PHF8 | Chr. | X chromosome (human) | 1.00 | infobox |
| PHF8 | Chr. | X chromosome (mouse) | 1.00 | infobox |
| PHF8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PHF8 | End | 54,048,958 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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