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PHD finger protein 8 is a protein that in humans is encoded by the PHF8 gene.
The analysis highlights Clinical significance, Function and Overview as prominent areas in the source structure around PHF8.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
A focused starting point derived from the topic graph, ranked independently of the source article order.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PHF8 shows recurring relationship patterns in the source. For example, PHF8 → 2-oxoglutarate-dependent dioxygenase activity, brain development, cell cycle, chromatin binding, chromatin organization, dioxygenase activity, G1/S transition of mitotic cell cycle, histone demethylase activity, histone H3-K27 demethylation, histone H3-K36 demethylation, histone H3-K9 demethylation, histone H3-methyl-lysine-36 demethylase activity, histone H3-methyl-lysine-9 demethylase activity, histone H3-tri/di-methyl-lysine-27 demethylase activity, histone H4-K20 demethylation, histone H4-methyl-lysine-20 demethylase activity, iron ion binding, metal ion binding, methylated histone binding, negative regulation of ribosomal DNA heterochromatin assembly Another extracted example is PHF8 → Achilles tendon, blood, epithelium of colon, gonad, Gonadal ridge, granulocyte, left testis, medial ganglionic eminence, otic placode, otic vesicle, primary oocyte, right lobe of liver, right testis, right uterine tube, saccule, secondary oocyte, sural nerve, tendon of biceps brachii, testicle, zygote. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
human bp gene chr band protein chromosome cleft lip activity location palate mouse phd finger function regulation external omim found
TTTA extracted 121 structured relationships around PHF8. Examples in this analysis include PHF8 → 1.14.11.65 → ↗ and PHF8 → Aliases → PHF8, JHDM1F, MRXSSD, ZNF422, PHD finger protein 8, KDM7B. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PHF8 | 1.14.11.65 | ↗ | 1.00 | infobox |
| PHF8 | Aliases | PHF8, JHDM1F, MRXSSD, ZNF422, PHD finger protein 8, KDM7B | 1.00 | infobox |
| PHF8 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4DO0, 3K3O, 2WWU, 3K3N, 3KV4,%%s2WWU, 3K3N, 3K3O, 3KV4, 4DO0 | 1.00 | infobox |
| PHF8 | Band | Xp11.22 | 1.00 | infobox |
| PHF8 | Band | X|X F3 | 1.00 | infobox |
| PHF8 | Bgee | right testis | 1.00 | infobox |
| PHF8 | Bgee | sural nerve | 1.00 | infobox |
| PHF8 | Bgee | left testis | 1.00 | infobox |
| PHF8 | Bgee | testicle | 1.00 | infobox |
| PHF8 | Bgee | tendon of biceps brachii | 1.00 | infobox |
| PHF8 | Bgee | Achilles tendon | 1.00 | infobox |
| PHF8 | Bgee | epithelium of colon | 1.00 | infobox |
| PHF8 | Bgee | right lobe of liver | 1.00 | infobox |
| PHF8 | Bgee | gonad | 1.00 | infobox |
| PHF8 | Bgee | right uterine tube | 1.00 | infobox |
| PHF8 | Bgee | zygote | 1.00 | infobox |
| PHF8 | Bgee | primary oocyte | 1.00 | infobox |
| PHF8 | Bgee | otic vesicle | 1.00 | infobox |
| PHF8 | Bgee | saccule | 1.00 | infobox |
| PHF8 | Bgee | blood | 1.00 | infobox |
| PHF8 | Bgee | secondary oocyte | 1.00 | infobox |
| PHF8 | Bgee | otic placode | 1.00 | infobox |
| PHF8 | Bgee | Gonadal ridge | 1.00 | infobox |
| PHF8 | Bgee | granulocyte | 1.00 | infobox |
| PHF8 | Bgee | medial ganglionic eminence | 1.00 | infobox |
| PHF8 | BioGPS | n/a | 1.00 | infobox |
| PHF8 | Chr. | X chromosome (human) | 1.00 | infobox |
| PHF8 | Chr. | X chromosome (mouse) | 1.00 | infobox |
| PHF8 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PHF8 | End | 54,048,958 bp | 1.00 | infobox |
The concept neighborhoods around PHF8 bring nearby vocabulary together. In this analysis, examples include Activity, Protein and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PHF8, one of the stronger structural bridges in this analysis connects PHF8 with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PHF8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PHF8 · EN edition · Analysis: TopicsToTalkAbout