Pendrin

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Overview

Anion exchange Protein Gene Formate Bicarbonate

19 related topics

Function

Thyroid follicular cells Na+/I− symporter Iodide (I−)Thyroid colloid Cortical collecting duct

6 related topics

Clinical significance

Deafness SLC26A3 Inflammation IL-13

4 related topics

Key facts & relationships

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Aliases: SLC26A4, DFNB4, EVA, PDS, TDH2B, solute carrier family 26 member 4
Band: 7q22.3 · 12|12 A2
Bgee: palpebral conjunctiva · right lobe of thyroid gland · left lobe of thyroid gland · Achilles tendon · Brodmann area 23
BioGPS: More reference expression data
Chr.: Chromosome 7 (human) · Chromosome 12 (mouse)
Databases: NCBI: entry; OMA: entry

Topics to explore

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Overview

Function

Thyroid follicular cells Thyroid follicular cell
Na+/I− symporter Sodium/iodide cotransporter
Iodide (I−) Iodide
Thyroid colloid
Cortical collecting duct
Β-intercalated cells Beta-intercalated cell

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

Nodes33

Edges32

Triples115

Avg. degree1.94

Density0.060606

Components1

How this topic connects Entity context

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Pendrin

Top relations

Gene ontology · 31

Pendrin → anion transmembrane transport, apical plasma membrane, bicarbonate transmembrane transporter activity, bicarbonate transport, brush border membrane, chloride channel activity, chloride transmembrane transport, chloride transmembrane transporter activity, chloride transport, extracellular exosome, hearing, inorganic anion transport, integral component of membrane, integral component of plasma membrane, iodide transmembrane transporter activity, iodide transport, ion transport, membrane, oxalate transmembrane transporter activity, oxalate transport

Bgee · 20

Pendrin → Achilles tendon, Brodmann area 23, ciliary body, cochlea, connecting tubule, glomerulus, human kidney, iris, kidney tubule, left lobe of thyroid gland, middle temporal gyrus, nasal epithelium, palpebral conjunctiva, right kidney, right lobe of thyroid gland, stria vascularis, testicle, utricle, vestibular membrane of cochlear duct, vestibular sensory epithelium

RNA expression pattern · 20

related to Clinical significance · 11

Pendrin → Another, Expression, IL-13, Mutations, Only, Pendred, SLC26A3, SLC26A4, The, These, This

related to Kidney · 6

Pendrin → Additionally, Cl, HCO3, Na, NaCl, Renal

is a · 3

Pendrin → anion exchange protein that in humans is encoded by the SLC26A4 gene, ion transporter, protein which is mutated in Pendred syndrome

Band · 2

Pendrin → 12|12 A2, 7q22.3

Chr. · 2

Pendrin → Chromosome 12 (mouse), Chromosome 7 (human)

End · 2

Pendrin → 107,717,809 bp, 31,609,968 bp

related to Thyroid · 2

Pendrin → In, Na

Important terminology Word statistics

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Important terminology

cells protein band bp gene human bicarbonate slc26a4 chr thyroid membrane kidney chromosome inner ear expression ion function pendred syndrome

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Pendrin	Aliases	SLC26A4, DFNB4, EVA, PDS, TDH2B, solute carrier family 26 member 4	1.00	infobox
Pendrin	Band	7q22.3	1.00	infobox
Pendrin	Band	12\|12 A2	1.00	infobox
Pendrin	Bgee	palpebral conjunctiva	1.00	infobox
Pendrin	Bgee	right lobe of thyroid gland	1.00	infobox
Pendrin	Bgee	left lobe of thyroid gland	1.00	infobox
Pendrin	Bgee	Achilles tendon	1.00	infobox
Pendrin	Bgee	Brodmann area 23	1.00	infobox
Pendrin	Bgee	kidney tubule	1.00	infobox
Pendrin	Bgee	nasal epithelium	1.00	infobox
Pendrin	Bgee	glomerulus	1.00	infobox
Pendrin	Bgee	testicle	1.00	infobox
Pendrin	Bgee	middle temporal gyrus	1.00	infobox
Pendrin	Bgee	ciliary body	1.00	infobox
Pendrin	Bgee	vestibular membrane of cochlear duct	1.00	infobox
Pendrin	Bgee	iris	1.00	infobox
Pendrin	Bgee	utricle	1.00	infobox
Pendrin	Bgee	vestibular sensory epithelium	1.00	infobox
Pendrin	Bgee	right kidney	1.00	infobox
Pendrin	Bgee	human kidney	1.00	infobox
Pendrin	Bgee	cochlea	1.00	infobox
Pendrin	Bgee	stria vascularis	1.00	infobox
Pendrin	Bgee	connecting tubule	1.00	infobox
Pendrin	BioGPS	More reference expression data	1.00	infobox
Pendrin	Chr.	Chromosome 7 (human)	1.00	infobox
Pendrin	Chr.	Chromosome 12 (mouse)	1.00	infobox
Pendrin	Databases	NCBI: entry; OMA: entry	1.00	infobox
Pendrin	End	107,717,809 bp	1.00	infobox
Pendrin	End	31,609,968 bp	1.00	infobox
Pendrin	Ensembl	ENSG00000091137	1.00	infobox

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