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Osilodrostat

Osilodrostat, sold under the brand name Isturisa, is a medication used for the treatment of adults with Cushing's disease who either cannot undergo pituitary gland surgery or have undergone the surgery but still have the disease. Osilodrostat is an orally active (taken by mouth), nonsteroidal corticosteroid biosynthesis inhibitor which was developed by…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
H02CA02 (WHO)
CAS Number
928134-65-0
ChEMBL
ChEMBL3099695
ChemSpider
29340911

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Overview

History

Advanced semantic analysis

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Map overview Semantic statistics

Osilodrostat

Nodes30
Edges29
Triples47
Avg. degree1.93
Density0.066667
Components1

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Osilodrostat

Top relations

related to history · 8
Osilodrostat → After, At, Cushing's, European Commission, In, In October, Osilodrostat's, The
related to External links · 7
Osilodrostat → Clinical, ClinicalTrials, Cushing's Disease, Efficacy, LINC-4, NCT02697734, Safety Evaluation
Legal status · 5
Osilodrostat → AU: S4 (Prescription only), CA: ℞-only, EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Legal status · 4
Osilodrostat → European Union, January, March, United States
KEGG · 2
Osilodrostat → D11061, D11062
3D model (JSmol) · 1
Osilodrostat → Interactive image
AHFS/Drugs.com · 1
Osilodrostat → Monograph
ATC code · 1
Osilodrostat → H02CA02 (WHO)
CAS Number · 1
Osilodrostat → 928134-65-0
ChEMBL · 1
Osilodrostat → ChEMBL3099695

Important terminology Word statistics

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Important terminology

subjects cushing's cortisol levels treatment disease drug inhibitor period trial pituitary weeks normal united states adrenal medication isturisa administration received

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Osilodrostat3D model (JSmol)Interactive image1.00infobox
OsilodrostatAHFS/Drugs.comMonograph1.00infobox
OsilodrostatATC codeH02CA02 (WHO)1.00infobox
OsilodrostatCAS Number928134-65-01.00infobox
OsilodrostatChEMBLChEMBL30996951.00infobox
OsilodrostatChemSpider293409111.00infobox
OsilodrostatCompTox Dashboard (EPA)DTXSID401565701.00infobox
OsilodrostatDrug classSteroidogenesis inhibitor1.00infobox
OsilodrostatDrugBankDB118371.00infobox
OsilodrostatFormulaC13H10FN31.00infobox
OsilodrostatKEGGD110621.00infobox
OsilodrostatKEGGD110611.00infobox
OsilodrostatLegal statusAU: S4 (Prescription only)1.00infobox
OsilodrostatLegal statusCA: ℞-only1.00infobox
OsilodrostatLegal statusUS: ℞-only1.00infobox
OsilodrostatLegal statusEU: Rx-only1.00infobox
OsilodrostatLegal statusIn general: ℞ (Prescription only)1.00infobox
OsilodrostatLicense dataUS DailyMed: Osilodrostat1.00infobox
OsilodrostatMedlinePlusa6250691.00infobox
OsilodrostatMolar mass227.242 g·mol−11.00infobox
OsilodrostatOther namesLCI-6991.00infobox
OsilodrostatPregnancy categoryAU: D1.00infobox
OsilodrostatPubChem CID441397521.00infobox
OsilodrostatRoutes of administrationBy mouth1.00infobox
OsilodrostatTrade namesIsturisa1.00infobox
OsilodrostatUNII5YL4IQ10781.00infobox
Osilodrostatis aorally active0.90text

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