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Olaratumab

Olaratumab, sold under the brand name Lartruvo, is a monoclonal antibody medication developed by Eli Lilly and Company for the treatment of solid tumors. It is directed against the platelet-derived growth factor receptor alpha.

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
L01FX10 (WHO)
CAS Number
1024603-93-7 N
ChemSpider
None
DrugBank
DB06043 Y
Elimination half-life
11 days

Topics to explore

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Overview

Medical uses

Contraindications

Side effects

Interactions

Pharmacology

History

Advanced semantic analysis

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Map overview Semantic statistics

Olaratumab

Nodes45
Edges44
Triples55
Avg. degree1.96
Density0.044444
Components1

How this topic connects Entity context

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Olaratumab

Top relations

related to Medical uses · 15
Olaratumab → ANNOUNCE, EMA, European Medicines Agency, FDA, German, German Physician's Medicines Commission, However, In, In April, January, Lilly, Shortly, STS, Therefore, United States
related to history · 12
Olaratumab → Eli Lilly, European Medicines Agency, European Union, ImClone Systems, In February, Japanese, November, October, Phase, Phase II, September, The European Commission
Legal status · 3
Olaratumab → CA: ℞-only, UK: POM (Prescription only), US: ℞-only
related to Interactions · 3
Olaratumab → Being, No, P450
has effect · 2
Olaratumab → Common, In
AHFS/Drugs.com · 1
Olaratumab → Monograph
ATC code · 1
Olaratumab → L01FX10 (WHO)
CAS Number · 1
Olaratumab → 1024603-93-7 N
ChemSpider · 1
Olaratumab → None
DrugBank · 1
Olaratumab → DB06043 Y

Important terminology Word statistics

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Important terminology

doxorubicin european 2019 antibody sarcoma trial patients phase drug lilly treatment united states fda lartruvo side effects medical uses infusion

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
OlaratumabAHFS/Drugs.comMonograph1.00infobox
OlaratumabATC codeL01FX10 (WHO)1.00infobox
OlaratumabCAS Number1024603-93-7 N1.00infobox
OlaratumabChemSpiderNone1.00infobox
OlaratumabDrugBankDB06043 Y1.00infobox
OlaratumabElimination half-life11 days1.00infobox
OlaratumabFormulaC6554H10076N1736O2048S401.00infobox
OlaratumabKEGGD09939 N1.00infobox
OlaratumabLegal statusCA: ℞-only1.00infobox
OlaratumabLegal statusUK: POM (Prescription only)1.00infobox
OlaratumabLegal statusUS: ℞-only1.00infobox
OlaratumabLicense dataUS DailyMed: Lartruvo1.00infobox
OlaratumabMetabolismProteolytic enzymes1.00infobox
OlaratumabMolar mass147241.21 g·mol−11.00infobox
OlaratumabOther namesIMC-3G3, LY-30122071.00infobox
OlaratumabProtein bindingNone1.00infobox
OlaratumabRoutes of administrationIntravenous infusion1.00infobox
OlaratumabSourceHuman1.00infobox
OlaratumabTargetPDGF-R α1.00infobox
OlaratumabTrade namesLartruvo1.00infobox
OlaratumabTypeWhole antibody1.00infobox
OlaratumabUNIITT6HN20MVF1.00infobox

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