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NDUFB4: Measurement, Structure & Function

NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa is a protein that in humans is encoded by the NDUFB4 gene. The NDUFB4 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.

Language: English [EN]
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NDUFB4 topic overview

The analysis highlights Measurement, Structure and Function as prominent areas in the source structure around NDUFB4.

Related topics
23
Source areas
3
Connected nodes
26
Extracted relationships
72
Concept neighborhoods
18
Bridge connections
26

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 9 topics
Structure · 9 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NDUFB4, B15, CI-B15, NADH:ubiquinone oxidoreductase subunit B4
Band
3q13.33
Bgee
right ventricle · biceps brachii · Skeletal muscle tissue of biceps brachii · Skeletal muscle tissue of rectus abdominis · body of tongue
BioGPS
n/a
Chr.
Chromosome 3 (human)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NDUFB4 connects Entity context

The extracted context around NDUFB4 shows recurring relationship patterns in the source. For example, NDUFB4 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, However, Initially, It, Mammalian, NADH, Q10, The, This Another extracted example is NDUFB4 → extracellular exosome, integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, nuclear membrane, respirasome, response to oxidative stress. Use these groups to spot repeated connection types before inspecting the individual relationships.

NDUFB4

Top relations

related to Function · 14
NDUFB4 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, However, Initially, It, Mammalian, NADH, Q10, The, This
Gene ontology · 12
NDUFB4 → extracellular exosome, integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, nuclear membrane, respirasome, response to oxidative stress
Bgee · 10
NDUFB4 → biceps brachii, body of tongue, cerebellar vermis, mucosa of sigmoid colon, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, thoracic diaphragm, triceps brachii muscle, vena cava
RNA expression pattern · 10
NDUFB4 → biceps brachii, body of tongue, cerebellar vermis, mucosa of sigmoid colon, right ventricle, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, thoracic diaphragm, triceps brachii muscle, vena cava
related to Structure · 8
NDUFB4 → C-terminal, Complex, It, L-shaped, N-terminal, NADH, The, The NDUFB4
is a · 2
NDUFB4 → accessory subunit of the complex that is believed not to be involved in catalysis, subunit of the enzyme NADH dehydrogenase
Aliases · 1
NDUFB4 → NDUFB4, B15, CI-B15, NADH:ubiquinone oxidoreductase subunit B4
Band · 1
NDUFB4 → 3q13.33
BioGPS · 1
NDUFB4 → n/a
Chr. · 1
NDUFB4 → Chromosome 3 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nadh ubiquinone protein complex dehydrogenase mitochondrial gene membrane subunit inner chain human chromosome bp hydrophobic electrons respiratory electron chr function

NDUFB4 relationships Subject–Predicate–Object triples

TTTA extracted 72 structured relationships around NDUFB4. Examples in this analysis include NDUFB4 → Aliases → NDUFB4, B15, CI-B15, NADH:ubiquinone oxidoreductase subunit B4 and NDUFB4 → Band → 3q13.33. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NDUFB4AliasesNDUFB4, B15, CI-B15, NADH:ubiquinone oxidoreductase subunit B41.00infobox
NDUFB4Band3q13.331.00infobox
NDUFB4Bgeeright ventricle1.00infobox
NDUFB4Bgeebiceps brachii1.00infobox
NDUFB4BgeeSkeletal muscle tissue of biceps brachii1.00infobox
NDUFB4BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
NDUFB4Bgeebody of tongue1.00infobox
NDUFB4Bgeethoracic diaphragm1.00infobox
NDUFB4Bgeetriceps brachii muscle1.00infobox
NDUFB4Bgeevena cava1.00infobox
NDUFB4Bgeemucosa of sigmoid colon1.00infobox
NDUFB4Bgeecerebellar vermis1.00infobox
NDUFB4BioGPSn/a1.00infobox
NDUFB4Chr.Chromosome 3 (human)1.00infobox
NDUFB4DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFB4End120,602,507 bp1.00infobox
NDUFB4EnsemblENSG000000655181.00infobox
NDUFB4Entrez47101.00infobox
NDUFB4External IDsOMIM: 603840; MGI: 3782046; GeneCards: NDUFB41.00infobox
NDUFB4Gene location (Human)Gene location (Human)Chr.Chromosome 3 (human)Band3q13.33Start120,596,328 bpEnd120,602,507 bp1.00infobox
NDUFB4Gene ontologyNADH dehydrogenase (ubiquinone) activity1.00infobox
NDUFB4Gene ontologyintegral component of membrane1.00infobox
NDUFB4Gene ontologymitochondrial inner membrane1.00infobox
NDUFB4Gene ontologymitochondrial respiratory chain complex I1.00infobox
NDUFB4Gene ontologyrespirasome1.00infobox
NDUFB4Gene ontologynuclear membrane1.00infobox
NDUFB4Gene ontologyextracellular exosome1.00infobox
NDUFB4Gene ontologymembrane1.00infobox
NDUFB4Gene ontologymitochondrion1.00infobox
NDUFB4Gene ontologyresponse to oxidative stress1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NDUFB4 bring nearby vocabulary together. In this analysis, examples include Subunit, Ubiquinone and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NDUFB4
    • Subunit
    • Ubiquinone
    • Protein
    • Human
    • Respiratory
    • Complex
    • Chain
    • Complexes
    • Largest
    • Located
    • Location
    • Transport
  • ndufb4
    • Subunit
    • Ubiquinone
    • Protein
    • Human
    • Respiratory
    • Complex
    • Chain
    • Complexes
    • Largest
    • Located
    • Location
    • Transport
  • protein
    • Mitochondrial
    • Ubiquinone
    • Chain
    • Inner
    • Membrane
    • Ndufb4
    • Activity
    • Located
    • Transport
    • Electron
    • Function
    • Complex
  • gene
    • Human
    • Location
    • Ubiquinone
    • Ndufb4
    • Bp
    • Chr
    • Chromosome
    • Function
    • Nadh
    • Respiratory
    • Chain
    • Subunit
  • nadh dehydrogenase (ubiquinone)
    • Protein
    • Nadh
    • Ubiquinone
    • Dehydrogenase
    • Ndufb4
    • Gene
    • Subunit
    • Electron
    • Function
    • Inner
    • Membrane
    • Respiratory
  • mitochondrial inner membrane
    • Membrane
    • Inner
    • Mitochondrial
    • Protein
    • Located
    • Transport
    • Chain
    • Domain
    • Electron
    • Function
    • Ubiquinone
    • Hydrophobic
  • electron transport chain
    • Located
    • Transport
    • Respiratory
    • Electrons
    • Mitochondrial
    • Ubiquinone
    • Activity
    • Band
    • Chain
    • Electron
    • Inner
    • Location
  • chromosome 3
    • Bp
    • Human
    • Band
    • Location
    • Function
    • Gene
    • Activity
    • Located
    • Long
    • Oxidoreductase
    • Transport
    • Ubiquinone

Connections between topic areas Semantic bridges

For NDUFB4, one of the stronger structural bridges in this analysis connects NDUFB4 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NDUFB4 — Structure · splits 17 ⟂ 10
NDUFB4 — Function · splits 17 ⟂ 10
NDUFB4 — Overview · splits 21 ⟂ 6

Map overview Semantic statistics

NDUFB4

Nodes27
Edges26
Triples72
Avg. degree1.93
Density0.074074
Components1

Source & methodology

TTTA analyzes the structure around NDUFB4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NDUFB4 · EN edition · Analysis: TopicsToTalkAbout

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