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NDUFA8: Measurement, Structure & Function

NADH dehydrogenase 1 alpha subcomplex subunit 8 is an enzyme that in humans is encoded by the NDUFA8 gene. The NDUFA8 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.

Language: English [EN]
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NDUFA8 topic overview

The analysis highlights Measurement, Structure and Function as prominent areas in the source structure around NDUFA8.

Related topics
25
Source areas
3
Connected nodes
28
Extracted relationships
87
Concept neighborhoods
17
Bridge connections
28

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 12 topics
Function · 8 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NDUFA8, CI-19KD, CI-PGIV, PGIV, NADH:ubiquinone oxidoreductase subunit A8, MC1DN37
Band
9q33.2 · 2|2 B
Bgee
apex of heart · left ventricle · right auricle of heart · right ventricle · muscle of thigh
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 2 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NDUFA8 connects Entity context

The extracted context around NDUFA8 shows recurring relationship patterns in the source. For example, NDUFA8 → anterior cingulate cortex, apex of heart, atrioventricular valve, caudate nucleus, digastric muscle, interventricular septum, left ventricle, muscle of thigh, myocardium, myocardium of left ventricle, myocardium of ventricle, right auricle of heart, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle Another extracted example is NDUFA8 → membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, protein-containing complex binding, respirasome. Use these groups to spot repeated connection types before inspecting the individual relationships.

NDUFA8

Top relations

Bgee · 19
NDUFA8 → anterior cingulate cortex, apex of heart, atrioventricular valve, caudate nucleus, digastric muscle, interventricular septum, left ventricle, muscle of thigh, myocardium, myocardium of left ventricle, myocardium of ventricle, right auricle of heart, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle
RNA expression pattern · 19
NDUFA8 → anterior cingulate cortex, apex of heart, atrioventricular valve, caudate nucleus, digastric muscle, interventricular septum, left ventricle, muscle of thigh, myocardium, myocardium of left ventricle, myocardium of ventricle, right auricle of heart, right kidney, right ventricle, Skeletal muscle tissue of biceps brachii, sternocleidomastoid muscle, temporal muscle, thoracic diaphragm, triceps brachii muscle
Gene ontology · 10
NDUFA8 → membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, protein-containing complex binding, respirasome
related to Function · 9
NDUFA8 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, NADH, Q10, The
related to Structure · 9
NDUFA8 → C-terminal, Complex, It, L-shaped, N-terminal, NADH, Related, The, The NDUFA8
Band · 2
NDUFA8 → 2|2 B, 9q33.2
Chr. · 2
NDUFA8 → Chromosome 2 (mouse), Chromosome 9 (human)
End · 2
NDUFA8 → 122,159,779 bp, 35,939,418 bp
Aliases · 1
NDUFA8 → NDUFA8, CI-19KD, CI-PGIV, PGIV, NADH:ubiquinone oxidoreductase subunit A8, MC1DN37
BioGPS · 1
NDUFA8 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nadh ubiquinone gene bp human protein mitochondrial dehydrogenase subunit chr band chromosome complex hydrophobic membrane inner chain structure location function

NDUFA8 relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around NDUFA8. Examples in this analysis include NDUFA8 → Aliases → NDUFA8, CI-19KD, CI-PGIV, PGIV, NADH:ubiquinone oxidoreductase subunit A8, MC1DN37 and NDUFA8 → Band → 9q33.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NDUFA8AliasesNDUFA8, CI-19KD, CI-PGIV, PGIV, NADH:ubiquinone oxidoreductase subunit A8, MC1DN371.00infobox
NDUFA8Band9q33.21.00infobox
NDUFA8Band2|2 B1.00infobox
NDUFA8Bgeeapex of heart1.00infobox
NDUFA8Bgeeleft ventricle1.00infobox
NDUFA8Bgeeright auricle of heart1.00infobox
NDUFA8Bgeeright ventricle1.00infobox
NDUFA8Bgeemuscle of thigh1.00infobox
NDUFA8Bgeecaudate nucleus1.00infobox
NDUFA8Bgeeanterior cingulate cortex1.00infobox
NDUFA8Bgeemyocardium1.00infobox
NDUFA8Bgeemyocardium of left ventricle1.00infobox
NDUFA8BgeeSkeletal muscle tissue of biceps brachii1.00infobox
NDUFA8Bgeedigastric muscle1.00infobox
NDUFA8Bgeetemporal muscle1.00infobox
NDUFA8Bgeesternocleidomastoid muscle1.00infobox
NDUFA8Bgeetriceps brachii muscle1.00infobox
NDUFA8Bgeemyocardium of ventricle1.00infobox
NDUFA8Bgeeatrioventricular valve1.00infobox
NDUFA8Bgeeinterventricular septum1.00infobox
NDUFA8Bgeeright kidney1.00infobox
NDUFA8Bgeethoracic diaphragm1.00infobox
NDUFA8BioGPSMore reference expression data1.00infobox
NDUFA8Chr.Chromosome 9 (human)1.00infobox
NDUFA8Chr.Chromosome 2 (mouse)1.00infobox
NDUFA8DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFA8End122,159,779 bp1.00infobox
NDUFA8End35,939,418 bp1.00infobox
NDUFA8EnsemblENSG000001194211.00infobox
NDUFA8Entrez47021.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NDUFA8 bring nearby vocabulary together. In this analysis, examples include Ubiquinone, Subunit and Respiratory. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NDUFA8
    • Ubiquinone
    • Subunit
    • Respiratory
    • Chain
    • Human
    • Complex
    • Complexes
    • Electron
    • Largest
    • Located
    • Transport
    • Function
  • ndufa8
    • Ubiquinone
    • Subunit
    • Respiratory
    • Chain
    • Human
    • Complex
    • Complexes
    • Electron
    • Largest
    • Located
    • Transport
    • Function
  • gene
    • Human
    • Location
    • Ndufa8
    • Ubiquinone
    • Chromosome
    • Bp
    • Chr
    • Subunit
    • Nadh
    • End
    • Mouse
    • Function
  • nadh dehydrogenase (ubiquinone)
    • Nadh
    • Ubiquinone
    • Ndufa8
    • Dehydrogenase
    • Subunit
    • Inner
    • Membrane
    • Gene
    • Function
    • Respiratory
    • Complexes
    • Electron
  • mitochondrial inner membrane
    • Membrane
    • Inner
    • Mitochondrial
    • Electron
    • Located
    • Protein
    • Transport
    • Chain
    • Complex
    • Function
    • Hydrophobic
    • Ubiquinone
  • electron transport chain
    • Located
    • Transport
    • Chain
    • Electron
    • Inner
    • Membrane
    • Mitochondrial
    • Protein
    • Respiratory
    • Ndufa8
    • Ubiquinone
    • Electrons
  • chromosome 9
    • Bp
    • Human
    • Location
    • Band
    • End
    • Mouse
    • Gene
    • Function
    • Ndufa8
    • Ubiquinone
    • Electron
    • Located
  • mitochondrial membrane
    • Inner
    • Membrane
    • Mitochondrial
    • Electron
    • Protein
    • Transport
    • Chain
    • Complex
    • Function
    • Hydrophobic
    • Ubiquinone
    • Domain

Connections between topic areas Semantic bridges

For NDUFA8, one of the stronger structural bridges in this analysis connects NDUFA8 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NDUFA8 — Structure · splits 16 ⟂ 13
NDUFA8 — Function · splits 20 ⟂ 9
NDUFA8 — Overview · splits 23 ⟂ 6

Map overview Semantic statistics

NDUFA8

Nodes29
Edges28
Triples87
Avg. degree1.93
Density0.068966
Components1

Source & methodology

TTTA analyzes the structure around NDUFA8 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NDUFA8 · EN edition · Analysis: TopicsToTalkAbout

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