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NDUFA6: Measurement, Structure & Function

NADH dehydrogenase 1 alpha subcomplex subunit 6 is an enzyme that in humans is encoded by the NDUFA6 gene. It belongs to the superfamily of LYRM proteins, which are characterized by a conserved leucine–tyrosine–arginine motif. The NDUFA6 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is…

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NDUFA6 topic overview

The analysis highlights Measurement, Structure and Function as prominent areas in the source structure around NDUFA6.

Related topics
31
Source areas
3
Connected nodes
34
Extracted relationships
88
Concept neighborhoods
18
Bridge connections
34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 12 topics
Overview · 11 topics
Function · 8 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NDUFA6, B14, CI-B14, LYRM6, NADHB14, NADH:ubiquinone oxidoreductase subunit A6, MC1DN33
Band
22q13.2 · 15|15 E1
Bgee
muscle of thigh · left ventricle · right auricle of heart · apex of heart · gastrocnemius muscle
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NDUFA6 connects Entity context

The extracted context around NDUFA6 shows recurring relationship patterns in the source. For example, NDUFA6 → apex of heart, atrioventricular valve, digastric muscle, facial motor nucleus, ganglionic eminence, gastrocnemius muscle, human kidney, intercostal muscle, left ventricle, mucosa of transverse colon, muscle of thigh, proximal tubule, renal cortex, right auricle of heart, right kidney, skeletal muscle tissue, sternocleidomastoid muscle, temporal muscle, triceps brachii muscle Another extracted example is NDUFA6 → membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, respirasome, response to oxidative stress. Use these groups to spot repeated connection types before inspecting the individual relationships.

NDUFA6

Top relations

Bgee · 19
NDUFA6 → apex of heart, atrioventricular valve, digastric muscle, facial motor nucleus, ganglionic eminence, gastrocnemius muscle, human kidney, intercostal muscle, left ventricle, mucosa of transverse colon, muscle of thigh, proximal tubule, renal cortex, right auricle of heart, right kidney, skeletal muscle tissue, sternocleidomastoid muscle, temporal muscle, triceps brachii muscle
RNA expression pattern · 19
NDUFA6 → apex of heart, atrioventricular valve, digastric muscle, facial motor nucleus, ganglionic eminence, gastrocnemius muscle, human kidney, intercostal muscle, left ventricle, mucosa of transverse colon, muscle of thigh, proximal tubule, renal cortex, right auricle of heart, right kidney, skeletal muscle tissue, sternocleidomastoid muscle, temporal muscle, triceps brachii muscle
Gene ontology · 10
NDUFA6 → membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial membranes, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, respirasome, response to oxidative stress
related to Function · 10
NDUFA6 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10, The
related to Structure · 9
NDUFA6 → C-terminal, Complex, It, L-shaped, N-terminal, NADH, Related, The, The NDUFA6
Band · 2
NDUFA6 → 15|15 E1, 22q13.2
Chr. · 2
NDUFA6 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
NDUFA6 → 42,090,884 bp, 82,238,523 bp
Aliases · 1
NDUFA6 → NDUFA6, B14, CI-B14, LYRM6, NADHB14, NADH:ubiquinone oxidoreductase subunit A6, MC1DN33
BioGPS · 1
NDUFA6 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nadh ubiquinone gene bp human protein mitochondrial dehydrogenase subunit chr band chromosome 22 complex hydrophobic membrane inner chain structure location

NDUFA6 relationships Subject–Predicate–Object triples

TTTA extracted 88 structured relationships around NDUFA6. Examples in this analysis include NDUFA6 → Aliases → NDUFA6, B14, CI-B14, LYRM6, NADHB14, NADH:ubiquinone oxidoreductase subunit A6, MC1DN33 and NDUFA6 → Band → 22q13.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NDUFA6AliasesNDUFA6, B14, CI-B14, LYRM6, NADHB14, NADH:ubiquinone oxidoreductase subunit A6, MC1DN331.00infobox
NDUFA6Band22q13.21.00infobox
NDUFA6Band15|15 E11.00infobox
NDUFA6Bgeemuscle of thigh1.00infobox
NDUFA6Bgeeleft ventricle1.00infobox
NDUFA6Bgeeright auricle of heart1.00infobox
NDUFA6Bgeeapex of heart1.00infobox
NDUFA6Bgeegastrocnemius muscle1.00infobox
NDUFA6Bgeeskeletal muscle tissue1.00infobox
NDUFA6Bgeehuman kidney1.00infobox
NDUFA6Bgeemucosa of transverse colon1.00infobox
NDUFA6Bgeeganglionic eminence1.00infobox
NDUFA6Bgeerenal cortex1.00infobox
NDUFA6Bgeeright kidney1.00infobox
NDUFA6Bgeefacial motor nucleus1.00infobox
NDUFA6Bgeedigastric muscle1.00infobox
NDUFA6Bgeeproximal tubule1.00infobox
NDUFA6Bgeetemporal muscle1.00infobox
NDUFA6Bgeeintercostal muscle1.00infobox
NDUFA6Bgeesternocleidomastoid muscle1.00infobox
NDUFA6Bgeeatrioventricular valve1.00infobox
NDUFA6Bgeetriceps brachii muscle1.00infobox
NDUFA6BioGPSMore reference expression data1.00infobox
NDUFA6Chr.Chromosome 22 (human)1.00infobox
NDUFA6Chr.Chromosome 15 (mouse)1.00infobox
NDUFA6DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFA6End42,090,884 bp1.00infobox
NDUFA6End82,238,523 bp1.00infobox
NDUFA6EnsemblENSG00000273397 ENSG00000184983 ENSG00000272765 ENSG00000281013 ENSG00000277365 n/a1.00infobox
NDUFA6Entrez47001.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NDUFA6 bring nearby vocabulary together. In this analysis, examples include Ubiquinone, Subunit and Respiratory. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NDUFA6
    • Ubiquinone
    • Subunit
    • Respiratory
    • Chain
    • Human
    • Complex
    • Complexes
    • Electron
    • Largest
    • Located
    • Transport
    • Function
  • ndufa6
    • Ubiquinone
    • Subunit
    • Respiratory
    • Chain
    • Human
    • Complex
    • Complexes
    • Electron
    • Largest
    • Located
    • Transport
    • Function
  • gene
    • Human
    • Location
    • Ndufa6
    • Ubiquinone
    • Chromosome
    • Bp
    • Chr
    • Subunit
    • Nadh
    • End
    • Mouse
    • Function
  • nadh dehydrogenase (ubiquinone)
    • Nadh
    • Ubiquinone
    • Ndufa6
    • Dehydrogenase
    • Subunit
    • Inner
    • Membrane
    • Gene
    • Function
    • Respiratory
    • Complexes
    • Electron
  • mitochondrial inner membrane
    • Membrane
    • Inner
    • Mitochondrial
    • Electron
    • Located
    • Protein
    • Transport
    • Chain
    • Complex
    • Function
    • Hydrophobic
    • Ubiquinone
  • electron transport chain
    • Located
    • Transport
    • Chain
    • Electron
    • Inner
    • Membrane
    • Mitochondrial
    • Protein
    • Respiratory
    • Ndufa6
    • Ubiquinone
    • Electrons
  • chromosome 22
    • Bp
    • Human
    • Location
    • Band
    • End
    • Mouse
    • Gene
    • Function
    • Ndufa6
    • Ubiquinone
    • Electron
    • Located
  • mitochondrial membrane
    • Inner
    • Membrane
    • Mitochondrial
    • Electron
    • Protein
    • Transport
    • Chain
    • Complex
    • Function
    • Hydrophobic
    • Ubiquinone
    • Domain

Connections between topic areas Semantic bridges

For NDUFA6, one of the stronger structural bridges in this analysis connects NDUFA6 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NDUFA6Structure · splits 22 ⟂ 13
NDUFA6Overview · splits 23 ⟂ 12
NDUFA6Function · splits 26 ⟂ 9

Map overview Semantic statistics

NDUFA6

Nodes35
Edges34
Triples88
Avg. degree1.94
Density0.057143
Components1

Source & methodology

TTTA analyzes the structure around NDUFA6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NDUFA6 · EN edition · Analysis: TopicsToTalkAbout

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