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NDUFA3: Measurement, Structure & Function

NADH dehydrogenase 1 alpha subcomplex subunit 3 is a protein that in humans is encoded by the NDUFA3 gene. The NDUFA3 protein is a subunit of NADH dehydrogenase (ubiquinone), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.

Language: English [EN]
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NDUFA3 topic overview

The analysis highlights Measurement, Structure and Function as prominent areas in the source structure around NDUFA3.

Related topics
25
Source areas
4
Connected nodes
29
Extracted relationships
62
Related term clusters
19
Bridge connections
29

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 11 topics
Function · 8 topics
Overview · 5 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
NDUFA3, B9, CI-B9, NADH:ubiquinone oxidoreductase subunit A3
Band
19q13.42
Bgee
primary visual cortex · muscle of thigh · superior frontal gyrus · apex of heart · putamen
BioGPS
n/a
Chr.
Chromosome 19 (human)
Databases
NCBI: entry; OMA: entry

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Function

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How NDUFA3 connects Entity context

The extracted context around NDUFA3 shows recurring relationship patterns in the source. For example, NDUFA3 → apex of heart, caudate nucleus, muscle of thigh, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, substantia nigra, superior frontal gyrus, temporal lobe Another extracted example is NDUFA3 → integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, respirasome. Use these groups to spot repeated connection types before inspecting the individual relationships.

NDUFA3

Top relations

Bgee · 10
NDUFA3 → apex of heart, caudate nucleus, muscle of thigh, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, substantia nigra, superior frontal gyrus, temporal lobe
RNA expression pattern · 10
NDUFA3 → apex of heart, caudate nucleus, muscle of thigh, nucleus accumbens, prefrontal cortex, primary visual cortex, putamen, substantia nigra, superior frontal gyrus, temporal lobe
Gene ontology · 9
NDUFA3 → integral component of membrane, membrane, mitochondrial electron transport, NADH to ubiquinone, mitochondrial inner membrane, mitochondrial respiratory chain complex I, mitochondrial respiratory chain complex I assembly, mitochondrion, NADH dehydrogenase (ubiquinone) activity, respirasome
related to Function · 9
NDUFA3 → Complex, CoQ, CoQH2, Fe-S, FMN, FMNH2, Initially, NADH, Q10
related to Structure · 6
NDUFA3 → C-terminal, Complex, L-shaped, N-terminal, NADH, The NDUFA3
is a · 2
NDUFA3 → accessory subunit of the complex that is believed not to be involved in catalysis, subunit of the enzyme NADH dehydrogenase
Aliases · 1
NDUFA3 → NDUFA3, B9, CI-B9, NADH:ubiquinone oxidoreductase subunit A3
Band · 1
NDUFA3 → 19q13.42
BioGPS · 1
NDUFA3 → n/a
Chr. · 1
NDUFA3 → Chromosome 19 (human)

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nadh ubiquinone protein subunit gene complex mitochondrial dehydrogenase human membrane inner chain chromosome 19 bp hydrophobic chr function arm domain

NDUFA3 relationships Subject–Predicate–Object triples

TTTA extracted 62 structured relationships around NDUFA3. Examples in this analysis include NDUFA3 → Aliases → NDUFA3, B9, CI-B9, NADH:ubiquinone oxidoreductase subunit A3 and NDUFA3 → Band → 19q13.42. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NDUFA3AliasesNDUFA3, B9, CI-B9, NADH:ubiquinone oxidoreductase subunit A31.00infobox
NDUFA3Band19q13.421.00infobox
NDUFA3Bgeeprimary visual cortex1.00infobox
NDUFA3Bgeemuscle of thigh1.00infobox
NDUFA3Bgeesuperior frontal gyrus1.00infobox
NDUFA3Bgeeapex of heart1.00infobox
NDUFA3Bgeeputamen1.00infobox
NDUFA3Bgeeprefrontal cortex1.00infobox
NDUFA3Bgeenucleus accumbens1.00infobox
NDUFA3Bgeecaudate nucleus1.00infobox
NDUFA3Bgeesubstantia nigra1.00infobox
NDUFA3Bgeetemporal lobe1.00infobox
NDUFA3BioGPSn/a1.00infobox
NDUFA3Chr.Chromosome 19 (human)1.00infobox
NDUFA3DatabasesNCBI: entry; OMA: entry1.00infobox
NDUFA3End54,109,257 bp1.00infobox
NDUFA3EnsemblENSG00000276061 ENSG00000273642 ENSG00000276220 ENSG00000278365 ENSG00000277722 ENSG00000276766 ENSG00000275605 ENSG00000274359 ENSG00000170906 ENSG000002757241.00infobox
NDUFA3Entrez46961.00infobox
NDUFA3External IDsOMIM: 603832; MGI: 1913341; GeneCards: NDUFA31.00infobox
NDUFA3Gene location (Human)Gene location (Human)Chr.Chromosome 19 (human)Band19q13.42Start54,102,728 bpEnd54,109,257 bp1.00infobox
NDUFA3Gene ontologyNADH dehydrogenase (ubiquinone) activity1.00infobox
NDUFA3Gene ontologyintegral component of membrane1.00infobox
NDUFA3Gene ontologymitochondrial inner membrane1.00infobox
NDUFA3Gene ontologymitochondrial respiratory chain complex I1.00infobox
NDUFA3Gene ontologyrespirasome1.00infobox
NDUFA3Gene ontologymembrane1.00infobox
NDUFA3Gene ontologymitochondrion1.00infobox
NDUFA3Gene ontologymitochondrial electron transport, NADH to ubiquinone1.00infobox
NDUFA3Gene ontologymitochondrial respiratory chain complex I assembly1.00infobox
NDUFA3Location (UCSC)Chr 19: 54.1 – 54.11 Mb1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around NDUFA3 bring nearby vocabulary together. In this analysis, examples include Subunit, Ubiquinone and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NDUFA3
    • Subunit
    • Ubiquinone
    • Protein
    • Complex
    • Respiratory
    • Chain
    • Human
    • Complexes
    • Electron
    • Largest
    • Located
    • Location
  • ndufa3
    • Subunit
    • Ubiquinone
    • Protein
    • Complex
    • Respiratory
    • Chain
    • Human
    • Complexes
    • Electron
    • Largest
    • Located
    • Location
  • protein
    • Mitochondrial
    • Ubiquinone
    • Chain
    • Inner
    • Membrane
    • Electron
    • Located
    • Ndufa3
    • Transport
    • Function
    • Subunit
    • Complex
  • gene
    • Human
    • Ndufa3
    • Ubiquinone
    • Location
    • Nadh
    • Protein
    • Subunit
    • Bp
    • Chr
    • Chromosome
    • Function
    • Respiratory
  • nadh dehydrogenase (ubiquinone)
    • Nadh
    • Ubiquinone
    • Subunit
    • Dehydrogenase
    • Ndufa3
    • Complexes
    • Electron
    • Gene
    • Largest
    • Located
    • Transport
    • Protein
  • mitochondrial inner membrane
    • Membrane
    • Inner
    • Mitochondrial
    • Protein
    • Chain
    • Electron
    • Located
    • Transport
    • Function
    • Complex
    • Ubiquinone
    • Domain
  • electron transport chain
    • Located
    • Transport
    • Chain
    • Electron
    • Inner
    • Membrane
    • Mitochondrial
    • Protein
    • Respiratory
    • Ubiquinone
    • Band
    • Dehydrogenase
  • nadh dehydrogenase
    • Ubiquinone
    • Complexes
    • Electron
    • Largest
    • Located
    • Subunit
    • Transport
    • Ndufa3
    • Nadh
    • Protein
    • Gene
    • Respiratory

Connections between topic areas Semantic bridges

For NDUFA3, one of the stronger structural bridges in this analysis connects NDUFA3 with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
NDUFA3 — Structure · splits 18 ⟂ 12
NDUFA3 — Function · splits 21 ⟂ 9
NDUFA3 — Overview · splits 24 ⟂ 6

Map overview Semantic statistics

NDUFA3

Nodes30
Edges29
Triples62
Avg. degree1.93
Density0.066667
Components1

Source & methodology

TTTA analyzes the structure around NDUFA3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NDUFA3 · EN edition · Analysis: TopicsToTalkAbout

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