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Nabilone

Nabilone, sold under the brand name Cesamet among others, is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. It mimics tetrahydrocannabinol (THC) and hexahydrocannabinol (HHC), two compounds found naturally in the plant genus Cannabis.

History & Applications

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
A04AD11 (WHO)
Bioavailability
20% after first-pass by the liver
CAS Number
51022-71-0 Y
ChEMBL
ChEMBL947 Y

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Overview

Medical uses

Side effects

Pharmacology

Chemistry

History

Advanced semantic analysis

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Map overview Semantic statistics

Nabilone

Nodes78
Edges77
Triples58
Avg. degree1.97
Density0.025641
Components1

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Nabilone

Top relations

related to history · 13
Nabilone → Cambridge Laboratories, Company, Eli Lilly, European Union, FDA, Germany, Health Canada, In, Lilly, Mexico, United Kingdom, Valeant, Valeant Pharmaceuticals
Legal status · 6
Nabilone → AU: S8 (Controlled drug), CA: Schedule II, DE: Anlage III (Special prescription form required), In general: ℞ (Prescription only), UK: POM (Prescription only), US: Schedule II
related to Pharmacodynamics · 3
Nabilone → CB1, CB2, THC
related to Pharmacokinetics · 3
Nabilone → It, Multiple, P450
3D model (JSmol) · 1
Nabilone → Interactive image
AHFS/Drugs.com · 1
Nabilone → Monograph
ATC code · 1
Nabilone → A04AD11 (WHO)
Bioavailability · 1
Nabilone → 20% after first-pass by the liver
CAS Number · 1
Nabilone → 51022-71-0 Y
ChEMBL · 1
Nabilone → ChEMBL947 Y

Important terminology Word statistics

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Important terminology

nausea pain multiple thc cannabinoid approved used chronic effects administration fda united vomiting modest sclerosis adjunct chemotherapy also fibromyalgia bioavailability

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nabilone3D model (JSmol)Interactive image1.00infobox
NabiloneAHFS/Drugs.comMonograph1.00infobox
NabiloneATC codeA04AD11 (WHO)1.00infobox
NabiloneBioavailability20% after first-pass by the liver1.00infobox
NabiloneCAS Number51022-71-0 Y1.00infobox
NabiloneChEMBLChEMBL947 Y1.00infobox
NabiloneChemSpider4447641 Y1.00infobox
NabiloneDrug classCannabinoid1.00infobox
NabiloneDrugBankDB00486 Y1.00infobox
NabiloneECHA InfoCard100.164.8241.00infobox
NabiloneElimination half-life2 hours, with metabolites around 35 hours1.00infobox
NabiloneFormulaC24H36O31.00infobox
NabiloneKEGGD05099 Y1.00infobox
NabiloneLegal statusAU: S8 (Controlled drug)1.00infobox
NabiloneLegal statusCA: Schedule II1.00infobox
NabiloneLegal statusDE: Anlage III (Special prescription form required)1.00infobox
NabiloneLegal statusUK: POM (Prescription only)1.00infobox
NabiloneLegal statusUS: Schedule II1.00infobox
NabiloneLegal statusIn general: ℞ (Prescription only)1.00infobox
NabiloneMedlinePlusa6070481.00infobox
NabiloneMolar mass372.549 g·mol−11.00infobox
NabiloneProtein bindingsimilar to THC (±97%)1.00infobox
NabilonePubChem CID52845921.00infobox
NabiloneRoutes of administrationBy mouth1.00infobox
NabiloneTrade namesCesamet, others1.00infobox
NabiloneUNII2N4O9L084N1.00infobox

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