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MutationTaster

MutationTaster is a free web-based application to evaluate DNA sequence variants for their disease-causing potential. The software performs a battery of in silico tests to estimate the impact of the variant on the gene product / protein. Tests are made on both, protein and DNA level, MutationTaster is hence not limited to substitutions of single amino…

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Authors
Jana Marie Schwarz and Dominik Seelow
Description
In silico tool to predict the disease-causing potential of DNA variants
Research center
Charité Berlin

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Overview

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Approach and tests

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Map overview Semantic statistics

MutationTaster

Nodes13
Edges12
Triples15
Avg. degree1.85
Density0.153846
Components1

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MutationTaster

Top relations

related to Development · 8
MutationTaster → Charité Berlin, Current, Daniela Hombach, Development, Dominik Seelow, Jana Marie Schwarz, Markus Schülke, Olivia Ebner
Authors · 1
MutationTaster → Jana Marie Schwarz and Dominik Seelow
Description · 1
MutationTaster → In silico tool to predict the disease-causing potential of DNA variants
Primary citation · 1
MutationTaster → .mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:r…
Research center · 1
MutationTaster → Charité Berlin
Website · 1
MutationTaster → www.mutationtaster.org
is a · 1
MutationTaster → free web-based application to evaluate DNA sequence variants for their disease-causing potential

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Important terminology

tests dna mutations gene single protein disease-causing variants potential harmless amino silico synonymous intronic background mutation effect prediction known methods

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MutationTasterAuthorsJana Marie Schwarz and Dominik Seelow1.00infobox
MutationTasterDescriptionIn silico tool to predict the disease-causing potential of DNA variants1.00infobox
MutationTasterPrimary citation.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:r…1.00infobox
MutationTasterResearch centerCharité Berlin1.00infobox
MutationTasterWebsitewww.mutationtaster.org1.00infobox
MutationTasteris afree web-based application to evaluate DNA sequence variants for their disease-causing potential0.90text
cancerinstance ofThese tools are not designed to predict sources of complex diseases0.80text
MutationTasterrelated to DevelopmentDevelopment0.60section
MutationTasterrelated to DevelopmentCharité Berlin0.60section
MutationTasterrelated to DevelopmentOlivia Ebner0.60section
MutationTasterrelated to DevelopmentDaniela Hombach0.60section
MutationTasterrelated to DevelopmentMarkus Schülke0.60section

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