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Methylnitronitrosoguanidine

Methylnitronitrosoguanidine (MNNG or MNG, NTG when referred to colloquially as nitrosoguanidine) is a biochemical tool used experimentally as a carcinogen and mutagen. It acts by adding alkyl groups to the O6 of guanine and O4 of thymine, which can lead to transition mutations between GC and AT. These changes do not cause a heavy distortion in the double…

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Nitrous acid
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Overview

CarcinogenMutagenAlkyl groupsGuanineThymine
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Methylnitronitrosoguanidine

Nodes13
Edges12
Triples0
Avg. degree1.85
Density0.153846
Components1

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mnng carcinogen used mutagen diazomethane references dna aqueous model formula standard state guanine thymine mng ntg referred colloquially nitrosoguanidine biochemical

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