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MLC1: Regions, Function & Overview

Membrane protein MLC1 (also called WKL1) is a protein that in humans is encoded by the MLC1 gene.

Language: English [EN]
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MLC1 topic overview

The analysis highlights Regions, Function and Overview as prominent areas in the source structure around MLC1.

Related topics
8
Source areas
2
Connected nodes
10
Extracted relationships
95
Related term clusters
10
Bridge connections
10

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics
Function · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MLC1, LVM, MLC, VL, megalencephalic leukoencephalopathy with subcortical cysts 1, modulator of VRAC current 1
Band
22q13.33 · 15|15 E3
Bgee
nucleus accumbens · ventricular zone · caudate nucleus · amygdala · putamen
BioGPS
More reference expression data
Chr.
Chromosome 22 (human) · Chromosome 15 (mouse)
Databases
NCBI: entry; OMA: entry

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MLC1
8Protein · Gene · Megalencephalic leukoencephalopathy with subcortical cysts

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How MLC1 connects Entity context

The extracted context around MLC1 shows recurring relationship patterns in the source. For example, MLC1 → apical plasma membrane, basolateral plasma membrane, caveola, caveolin-mediated endocytosis, cell-cell junction, cellular response to cholesterol, clathrin-coated vesicle, cytoplasm, cytoplasmic vesicle, early endosome, endoplasmic reticulum, endosome, integral component of membrane, ion transport, lysosome, membrane, membrane raft, perinuclear region of cytoplasm, plasma membrane, positive regulation of intracellular transport Another extracted example is MLC1 → amygdala, anterior cingulate cortex, arcuate nucleus, Brodmann area 9, caudate nucleus, deep cerebellar nuclei, dentate gyrus of hippocampal formation granule cell, globus pallidus, hypothalamus, mammillary body, median eminence, nucleus accumbens, nucleus of stria terminalis, optic nerve, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, putamen, right frontal lobe, spermatocyte, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

MLC1

Top relations

Gene ontology · 27
MLC1 → apical plasma membrane, basolateral plasma membrane, caveola, caveolin-mediated endocytosis, cell-cell junction, cellular response to cholesterol, clathrin-coated vesicle, cytoplasm, cytoplasmic vesicle, early endosome, endoplasmic reticulum, endosome, integral component of membrane, ion transport, lysosome, membrane, membrane raft, perinuclear region of cytoplasm, plasma membrane, positive regulation of intracellular transport
Bgee · 20
MLC1 → amygdala, anterior cingulate cortex, arcuate nucleus, Brodmann area 9, caudate nucleus, deep cerebellar nuclei, dentate gyrus of hippocampal formation granule cell, globus pallidus, hypothalamus, mammillary body, median eminence, nucleus accumbens, nucleus of stria terminalis, optic nerve, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, putamen, right frontal lobe, spermatocyte, ventricular zone
RNA expression pattern · 20
MLC1 → amygdala, anterior cingulate cortex, arcuate nucleus, Brodmann area 9, caudate nucleus, deep cerebellar nuclei, dentate gyrus of hippocampal formation granule cell, globus pallidus, hypothalamus, mammillary body, median eminence, nucleus accumbens, nucleus of stria terminalis, optic nerve, paraflocculus of cerebellum, paraventricular nucleus of hypothalamus, putamen, right frontal lobe, spermatocyte, ventricular zone
related to Function · 8
MLC1 → Furthermore, KCNA1, Kv1, Mutations, S1, S5, S6, The MLC1
Band · 2
MLC1 → 15|15 E3, 22q13.33
Chr. · 2
MLC1 → Chromosome 15 (mouse), Chromosome 22 (human)
End · 2
MLC1 → 50,085,902 bp, 88,863,210 bp
Aliases · 1
MLC1 → MLC1, LVM, MLC, VL, megalencephalic leukoencephalopathy with subcortical cysts 1, modulator of VRAC current 1
BioGPS · 1
MLC1 → More reference expression data
Databases · 1
MLC1 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band chromosome 22 protein megalencephalic leukoencephalopathy subcortical cysts membrane location function mouse mlc external associated 085

MLC1 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around MLC1. Examples in this analysis include MLC1 → Aliases → MLC1, LVM, MLC, VL, megalencephalic leukoencephalopathy with subcortical cysts 1, modulator of VRAC current 1 and MLC1 → Band → 22q13.33. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MLC1AliasesMLC1, LVM, MLC, VL, megalencephalic leukoencephalopathy with subcortical cysts 1, modulator of VRAC current 11.00infobox
MLC1Band22q13.331.00infobox
MLC1Band15|15 E31.00infobox
MLC1Bgeenucleus accumbens1.00infobox
MLC1Bgeeventricular zone1.00infobox
MLC1Bgeecaudate nucleus1.00infobox
MLC1Bgeeamygdala1.00infobox
MLC1Bgeeputamen1.00infobox
MLC1Bgeeright frontal lobe1.00infobox
MLC1Bgeeparaflocculus of cerebellum1.00infobox
MLC1BgeeBrodmann area 91.00infobox
MLC1Bgeeanterior cingulate cortex1.00infobox
MLC1Bgeehypothalamus1.00infobox
MLC1Bgeeoptic nerve1.00infobox
MLC1Bgeearcuate nucleus1.00infobox
MLC1Bgeemedian eminence1.00infobox
MLC1Bgeedeep cerebellar nuclei1.00infobox
MLC1Bgeeglobus pallidus1.00infobox
MLC1Bgeeparaventricular nucleus of hypothalamus1.00infobox
MLC1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
MLC1Bgeespermatocyte1.00infobox
MLC1Bgeemammillary body1.00infobox
MLC1Bgeenucleus of stria terminalis1.00infobox
MLC1BioGPSMore reference expression data1.00infobox
MLC1Chr.Chromosome 22 (human)1.00infobox
MLC1Chr.Chromosome 15 (mouse)1.00infobox
MLC1DatabasesNCBI: entry; OMA: entry1.00infobox
MLC1End50,085,902 bp1.00infobox
MLC1End88,863,210 bp1.00infobox
MLC1EnsemblENSG000001004271.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around MLC1 bring nearby vocabulary together. In this analysis, examples include Protein, Cysts and Leukoencephalopathy. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MLC1
    • Protein
    • Cysts
    • Leukoencephalopathy
    • Megalencephalic
    • Subcortical
    • Channel
    • Entry
    • Function
    • Homology
    • May
    • Mlc
    • Ncbi
  • mlc1
    • Protein
    • Cysts
    • Leukoencephalopathy
    • Megalencephalic
    • Subcortical
    • Channel
    • Entry
    • Function
    • Homology
    • May
    • Mlc
    • Ncbi
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Function
    • Membrane
    • Mouse
    • Mlc1
    • Protein
    • Band
  • function
    • Location
    • Chromosome
    • Human
    • Integral
    • Transport
    • Bp
    • Chr
    • Gene
    • End
    • Entry
    • Homology
    • May
  • membrane transport protein
    • Integral
    • Protein
    • Region
    • Also
    • End
    • Entry
    • Function
    • Homology
    • May
    • Membrane
    • Mouse
    • Ncbi
  • megalencephalic leukoencephalopathy with subcortical cysts
    • Cysts
    • Leukoencephalopathy
    • Megalencephalic
    • Subcortical
    • Mlc
    • Mlc1
    • Gene
    • External
    • Channel
    • Entry
    • Function
    • May
  • protein
    • Region
    • Transport
    • Ncbi
    • Suggests
  • gprc5b
    • Aqp4
    • Hepacam

Connections between topic areas Semantic bridges

For MLC1, one of the stronger structural bridges in this analysis connects MLC1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MLC1 — Overview · splits 4 ⟂ 7
MLC1 — Function · splits 8 ⟂ 3

Map overview Semantic statistics

MLC1

Nodes11
Edges10
Triples95
Avg. degree1.82
Density0.181818
Components1

Source & methodology

TTTA analyzes the structure around MLC1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MLC1 · EN edition · Analysis: TopicsToTalkAbout

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