Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Mibefradil: Overview, Related Topics & Entities

Mibefradil (trade name Posicor) was a pharmaceutical drug used for the treatment of hypertension and chronic angina pectoris. It is a nonselective calcium channel blocker. It was voluntary pulled from the market ten months after FDA approval, citing potential serious health hazards shown in post release studies.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Mibefradil topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around Mibefradil.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
25
Concept neighborhoods
9
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Micromedex Detailed Consumer Information
ATC code
C08CX01 (WHO)
Bioavailability
70%
CAS Number
116644-53-2 Y
ChEMBL
ChEMBL45816 N

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Mibefradil connects Entity context

The extracted context around Mibefradil shows recurring relationship patterns in the source. For example, Mibefradil → Interactive image Another extracted example is Mibefradil → Micromedex Detailed Consumer Information. Use these groups to spot repeated connection types before inspecting the individual relationships.

Mibefradil

Top relations

3D model (JSmol) · 1
Mibefradil → Interactive image
AHFS/Drugs.com · 1
Mibefradil → Micromedex Detailed Consumer Information
ATC code · 1
Mibefradil → C08CX01 (WHO)
Bioavailability · 1
Mibefradil → 70%
CAS Number · 1
Mibefradil → 116644-53-2 Y
ChEMBL · 1
Mibefradil → ChEMBL45816 N
ChemSpider · 1
Mibefradil → 54673 N
CompTox Dashboard (EPA) · 1
Mibefradil → DTXSID1023318
DrugBank · 1
Mibefradil → DB01388 N
Elimination half-life · 1
Mibefradil → 17–25 hours

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

market drug calcium voluntary fda approval potential trade name posicor synthesis hypertension t-type l-type roche pharmaceutical used treatment chronic angina

Mibefradil relationships Subject–Predicate–Object triples

TTTA extracted 25 structured relationships around Mibefradil. Examples in this analysis include Mibefradil → 3D model (JSmol) → Interactive image and Mibefradil → AHFS/Drugs.com → Micromedex Detailed Consumer Information. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Mibefradil3D model (JSmol)Interactive image1.00infobox
MibefradilAHFS/Drugs.comMicromedex Detailed Consumer Information1.00infobox
MibefradilATC codeC08CX01 (WHO)1.00infobox
MibefradilBioavailability70%1.00infobox
MibefradilCAS Number116644-53-2 Y1.00infobox
MibefradilChEMBLChEMBL45816 N1.00infobox
MibefradilChemSpider54673 N1.00infobox
MibefradilCompTox Dashboard (EPA)DTXSID10233181.00infobox
MibefradilDrugBankDB01388 N1.00infobox
MibefradilElimination half-life17–25 hours1.00infobox
MibefradilFormulaC29H38FN3O31.00infobox
MibefradilIUPHAR/BPS25221.00infobox
MibefradilKEGGD08217 Y1.00infobox
MibefradilLegal statusWithdrawn from market1.00infobox
MibefradilMedlinePlusa6070071.00infobox
MibefradilMelting point128 °C (262 °F) (dihydrochloride salt)1.00infobox
MibefradilMetabolismLiver (CYP3A4)1.00infobox
MibefradilMolar mass495.639 g·mol−11.00infobox
MibefradilPDB ligandMWV (PDBe, RCSB PDB)1.00infobox
MibefradilProtein binding>99%1.00infobox
MibefradilPubChem CID606621.00infobox
MibefradilRoutes of administrationBy mouth (tablets)1.00infobox
MibefradilTrade namesPosicor1.00infobox
MibefradilUNII27B90X776A1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Mibefradil bring nearby vocabulary together. In this analysis, examples include Drug, Name and Posicor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Mibefradil
    • Drug
    • Name
    • Posicor
    • Trade
    • Market
    • Action
    • Angina
    • Characterized
    • Chronic
    • Hypertension
    • L-type
    • Mechanism
  • mibefradil
    • Drug
    • Name
    • Posicor
    • Trade
    • Market
    • Action
    • Angina
    • Characterized
    • Chronic
    • Hypertension
    • L-type
    • Mechanism
  • pharmaceutical drug
    • Pectoris
    • Treatment
    • Used
    • Mibefradil
    • Action
    • Angina
    • Characterized
    • Chronic
    • Hypertension
    • L-type
    • Mechanism
    • Pharmaceutical
  • calcium channel blocker
    • Blocker
    • Channel
    • Nonselective
    • Action
    • Calcium
    • Characterized
    • L-type
    • Mechanism
    • Roche
    • Selective
    • T-type
    • Approval
  • angina pectoris
    • Chronic
    • Hypertension
    • Pectoris
    • Pharmaceutical
    • Treatment
    • Used
    • Drug
    • Name
    • Posicor
    • Trade
    • Mibefradil
  • hypertension
    • Angina
    • Chronic
    • Pectoris
    • Pharmaceutical
    • Treatment
    • Used
    • Name
    • Posicor
    • Trade
    • Mibefradil
  • l-type
    • Mechanism
    • Roche
    • Selective
    • T-type
    • Potential
    • Voluntary
    • Market
    • Mibefradil
  • roche
    • Selective
    • T-type
    • Voluntary

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Mibefradil map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Mibefradil

Nodes9
Edges8
Triples25
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around Mibefradil to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Mibefradil · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.