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Mesuximide

Mesuximide (or methsuximide, methosuximide) is a succinimide anticonvulsant medication. It is sold as a racemate by Pfizer under the tradenames Petinutin (Switzerland) and Celontin (United States). The therapeutic efficacy of methosuximide is largely due to its pharmacologically active metabolite, N-desmethylmethosuximide, which has a longer half-life…

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Medical use

1 related topics

Overview

4 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Consumer Drug Information
ATC code
N03AD03 (WHO)
CAS Number
77-41-8 Y
ChEMBL
ChEMBL697 Y
ChemSpider
6231 Y

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Overview

Medical use

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Map overview Semantic statistics

Mesuximide

Nodes8
Edges7
Triples24
Avg. degree1.75
Density0.25
Components1

How this topic connects Entity context

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Mesuximide

Top relations

3D model (JSmol) · 1
Mesuximide → Interactive image
AHFS/Drugs.com · 1
Mesuximide → Consumer Drug Information
ATC code · 1
Mesuximide → N03AD03 (WHO)
CAS Number · 1
Mesuximide → 77-41-8 Y
ChEMBL · 1
Mesuximide → ChEMBL697 Y
ChemSpider · 1
Mesuximide → 6231 Y
Chirality · 1
Mesuximide → Racemic mixture
CompTox Dashboard (EPA) · 1
Mesuximide → DTXSID5023293
DrugBank · 1
Mesuximide → DB05246 N
ECHA InfoCard · 1
Mesuximide → 100.000.934

Important terminology Word statistics

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Important terminology

methosuximide celontin active metabolite n-desmethylmethosuximide half-life medical use drugs succinimide anticonvulsant racemate pfizer methsuximide medication sold tradenames petinutin switzerland united

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Mesuximide3D model (JSmol)Interactive image1.00infobox
MesuximideAHFS/Drugs.comConsumer Drug Information1.00infobox
MesuximideATC codeN03AD03 (WHO)1.00infobox
MesuximideCAS Number77-41-8 Y1.00infobox
MesuximideChEMBLChEMBL697 Y1.00infobox
MesuximideChemSpider6231 Y1.00infobox
MesuximideChiralityRacemic mixture1.00infobox
MesuximideCompTox Dashboard (EPA)DTXSID50232931.00infobox
MesuximideDrugBankDB05246 N1.00infobox
MesuximideECHA InfoCard100.000.9341.00infobox
MesuximideElimination half-life1.4–2.6 hours (mesuximide) 28–38 hours (active metabolite)1.00infobox
MesuximideExcretionUrine1.00infobox
MesuximideFormulaC12H13NO21.00infobox
MesuximideIUPHAR/BPS72281.00infobox
MesuximideKEGGD00404 Y1.00infobox
MesuximideLegal statusUS: ℞-only1.00infobox
MesuximideMedlinePlusa6820281.00infobox
MesuximideMetabolismHepatic (demethylation and glucuronidation)1.00infobox
MesuximideMetabolitesN-desmethylmethosuximide1.00infobox
MesuximideMolar mass203.241 g·mol−11.00infobox
MesuximidePubChem CID64761.00infobox
MesuximideRoutes of administrationBy mouth (capsules)1.00infobox
MesuximideTrade namesCelontin1.00infobox
MesuximideUNII0G76K8X6C01.00infobox

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