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Mesuximide (or methsuximide, methosuximide) is a succinimide anticonvulsant medication. It is sold as a racemate by Pfizer under the tradenames Petinutin (Switzerland) and Celontin (United States). The therapeutic efficacy of methosuximide is largely due to its pharmacologically active metabolite, N-desmethylmethosuximide, which has a longer half-life…
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methosuximide celontin active metabolite n-desmethylmethosuximide half-life medical use drugs succinimide anticonvulsant racemate pfizer methsuximide medication sold tradenames petinutin switzerland united
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Mesuximide | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Mesuximide | AHFS/Drugs.com | Consumer Drug Information | 1.00 | infobox |
| Mesuximide | ATC code | N03AD03 (WHO) | 1.00 | infobox |
| Mesuximide | CAS Number | 77-41-8 Y | 1.00 | infobox |
| Mesuximide | ChEMBL | ChEMBL697 Y | 1.00 | infobox |
| Mesuximide | ChemSpider | 6231 Y | 1.00 | infobox |
| Mesuximide | Chirality | Racemic mixture | 1.00 | infobox |
| Mesuximide | CompTox Dashboard (EPA) | DTXSID5023293 | 1.00 | infobox |
| Mesuximide | DrugBank | DB05246 N | 1.00 | infobox |
| Mesuximide | ECHA InfoCard | 100.000.934 | 1.00 | infobox |
| Mesuximide | Elimination half-life | 1.4–2.6 hours (mesuximide) 28–38 hours (active metabolite) | 1.00 | infobox |
| Mesuximide | Excretion | Urine | 1.00 | infobox |
| Mesuximide | Formula | C12H13NO2 | 1.00 | infobox |
| Mesuximide | IUPHAR/BPS | 7228 | 1.00 | infobox |
| Mesuximide | KEGG | D00404 Y | 1.00 | infobox |
| Mesuximide | Legal status | US: ℞-only | 1.00 | infobox |
| Mesuximide | MedlinePlus | a682028 | 1.00 | infobox |
| Mesuximide | Metabolism | Hepatic (demethylation and glucuronidation) | 1.00 | infobox |
| Mesuximide | Metabolites | N-desmethylmethosuximide | 1.00 | infobox |
| Mesuximide | Molar mass | 203.241 g·mol−1 | 1.00 | infobox |
| Mesuximide | PubChem CID | 6476 | 1.00 | infobox |
| Mesuximide | Routes of administration | By mouth (capsules) | 1.00 | infobox |
| Mesuximide | Trade names | Celontin | 1.00 | infobox |
| Mesuximide | UNII | 0G76K8X6C0 | 1.00 | infobox |
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