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M1G

M1G (pyrimidopurin-10(3H)-one) is a heterocyclic compound which is a by-product of base excision repair (BER) of a specific type of DNA adduct called M1dG. The M1dG adduct in turn is formed by a condensation reaction between guanosine nucleotides in DNA and either malondialdehyde (propanedial) or acrolein. If not repaired, these adducts are mutagenic and…

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M1G

Nodes22
Edges21
Triples1
Avg. degree1.91
Density0.090909
Components1

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M1G

Top relations

is a · 1
M1G → tool for detecting DNA damage that may lead to cancer

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Important terminology

dna m1dg adduct adducts pyrimido purin-10 3h -one nucleotides malondialdehyde acrolein 2-a free mesh references standard state by-product guanosine mutagenic

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
M1Gis atool for detecting DNA damage that may lead to cancer0.90text

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