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Ly49

Ly49 is a family of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells (some CD8+ and CD3+ T lymphocytes, intestinal epithelial lymphocytes (IELs), NKT cells, uterine NK cells (uNK) cells, macrophages or dendritic cells). Their primary role is to bind MHC-I molecules to distinguish between self healthy cells…

Overview, Receptor types & Function

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Overview

Function

Receptor types

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Map overview Semantic statistics

Ly49

Nodes40
Edges39
Triples24
Avg. degree1.95
Density0.05
Components1

How this topic connects Entity context

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Ly49

Top relations

related to Role in NK cells · 10
Ly49 → In, Ly49H, MCMV, Mouse, NK, Some Ly49, The, Therefore, They, This
related to Inhibitory receptors · 7
Ly49 → Inhibitory, ITIM, NK, Phosphorylated Ly49, SH2, SHP-1, Stimulation
related to Activating receptors · 6
Ly49 → Activating, After, DAP-12, ITAM, SH2, They
is a · 1
Ly49 → family of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells

Important terminology Word statistics

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Important terminology

receptors cells nk inhibitory activating cell molecules role activation self infected include recognise family recognition viral humans function gene ligands

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Ly49is afamily of membrane C-type lectin-like receptors expressed mainly on NK cells but also on other immune cells0.90text
Ly49related to Activating receptorsActivating0.60section
Ly49related to Activating receptorsThey0.60section
Ly49related to Activating receptorsITAM0.60section
Ly49related to Activating receptorsDAP-120.60section
Ly49related to Activating receptorsAfter0.60section
Ly49related to Activating receptorsSH20.60section
Ly49related to Inhibitory receptorsInhibitory0.60section
Ly49related to Inhibitory receptorsNK0.60section
Ly49related to Inhibitory receptorsStimulation0.60section
Ly49related to Inhibitory receptorsITIM0.60section
Ly49related to Inhibitory receptorsPhosphorylated Ly490.60section

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