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Lonidamine

Lonidamine is a derivative of indazole-3-carboxylic acid, which for a long time, has been known to inhibit aerobic glycolysis in cancer cells. It seems to enhance aerobic glycolysis in normal cells, but suppress glycolysis in cancer cells. This is most likely through the inhibition of the mitochondrially bound hexokinase. Later studies in Ehrlich ascites…

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3D model (JSmol)
Interactive image
ATC code
L01XX07 (WHO)
CAS Number
50264-69-2 Y
ChEBI
CHEBI:50138
ChemSpider
36170 N
CompTox Dashboard (EPA)
DTXSID5020782

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Lonidamine

Nodes8
Edges7
Triples13
Avg. degree1.75
Density0.25
Components1

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Lonidamine

Top relations

3D model (JSmol) · 1
Lonidamine → Interactive image
ATC code · 1
Lonidamine → L01XX07 (WHO)
CAS Number · 1
Lonidamine → 50264-69-2 Y
ChEBI · 1
Lonidamine → CHEBI:50138
ChemSpider · 1
Lonidamine → 36170 N
CompTox Dashboard (EPA) · 1
Lonidamine → DTXSID5020782
ECHA InfoCard · 1
Lonidamine → 100.051.356
Formula · 1
Lonidamine → C15H10Cl2N2O2
KEGG · 1
Lonidamine → D07257 Y
Molar mass · 1
Lonidamine → 321.16 g·mol−1

Important terminology Word statistics

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Important terminology

cells glycolysis inhibit cancer combination derivative aerobic enhance showed anticancer agents brain tumours temozolomide acid normal hexokinase gamendazole indazole-3-carboxylic long

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Lonidamine3D model (JSmol)Interactive image1.00infobox
LonidamineATC codeL01XX07 (WHO)1.00infobox
LonidamineCAS Number50264-69-2 Y1.00infobox
LonidamineChEBICHEBI:501381.00infobox
LonidamineChemSpider36170 N1.00infobox
LonidamineCompTox Dashboard (EPA)DTXSID50207821.00infobox
LonidamineECHA InfoCard100.051.3561.00infobox
LonidamineFormulaC15H10Cl2N2O21.00infobox
LonidamineKEGGD07257 Y1.00infobox
LonidamineMolar mass321.16 g·mol−11.00infobox
LonidaminePubChem CID395621.00infobox
LonidamineUNIIU78804BIDR1.00infobox
Lonidamineis aderivative of indazole-3-carboxylic acid0.90text

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