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Elevated transaminases

In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. Other terms include transaminasemia, and elevated liver enzymes (though they are not the only enzymes in the liver). Normal ranges for both ALT and AST vary by gender, age…

Art, Pathophysiology & Magnitude of AST and ALT elevations

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Pathophysiology

Role in diagnosis

Magnitude of AST and ALT elevations

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Elevated transaminases

Nodes38
Edges37
Triples6
Avg. degree1.95
Density0.052632
Components1

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Important terminology

liver alt ast transaminases elevated levels muscle transaminase may commonly alanine aspartate enzymes normal elevations hepatitis however disease values also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
isoniazid are limited typically to below 100 U/L for either ALT or ASTinstance ofDrug-induced increases such as that found with the use of anti-tuberculosis agents0.80text
thyroid disordersinstance ofthey may also be elevated in other conditions0.80text
celiac diseaseinstance ofthey may also be elevated in other conditions0.80text
and muscle disorders.ALT is usually found only in the liverinstance ofthey may also be elevated in other conditions0.80text
weight lifting can increase ALT to 50-200 U/Linstance ofintense exercise0.80text
and AST to 100-1000 U/L for the week following the exerciseinstance ofintense exercise0.80text

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