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Lecanemab

Lecanemab, sold under the brand name Leqembi, is a monoclonal antibody medication used for the treatment of mild Alzheimer's disease. Lecanemab is an amyloid beta-directed antibody. It is given via intravenous infusion or subcutaneous injection. In clinical trials, it demonstrated small or no clinically significant efficacy in Alzheimer's disease. The…

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
N06DX04 (WHO)
CAS Number
1260393-98-3
ChemSpider
none
DrugBank
DB14580
Formula
C6544H10088N1744O2032S46

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Overview

Medical uses

Adverse effects

Pharmacology

History

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Map overview Semantic statistics

Lecanemab

Nodes57
Edges56
Triples82
Avg. degree1.96
Density0.035088
Components1

How this topic connects Entity context

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Lecanemab

Top relations

related to Economics · 16
Lecanemab → According, After, Alzheimer's, As, At, California Technology Assessment Forum, Clinical, Economic Review, Eisai, However, ICER, Institute, Medicare, This, United States, US
related to Legal status · 11
Lecanemab → April, Canada, December, EU, January, July, May, Mexico, October, South Korea, United States
related to history · 7
Lecanemab → Biogen, Drug Administration, FDA, III, In July, In September, US Food
related to Reception · 6
Lecanemab → Do Not Use, FDA, Group, In October, It, Public Citizen's Health Research
related to Research · 5
Lecanemab → Alzheimer's, BioArctic, Biogen, Eisai, It
Legal status · 4
Lecanemab → CA: ℞-only / Schedule D, EU: Rx-only, Rx-only, US: ℞-only
has effect · 3
Lecanemab → ARIA, Compared, However
is a · 2
Lecanemab → amyloid beta-directed antibody, humanized monoclonal antibody consisting of a humanized version of a mouse antibody
related to Efficacy · 2
Lecanemab → Alzheimer's, Cochrane
AHFS/Drugs.com · 1
Lecanemab → Monograph

Important terminology Word statistics

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Important terminology

alzheimer's disease treatment amyloid clinical people fda mild eisai may approval participants small leqembi dementia placebo antibody cognitive 2023 2025

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
LecanemabAHFS/Drugs.comMonograph1.00infobox
LecanemabATC codeN06DX04 (WHO)1.00infobox
LecanemabCAS Number1260393-98-31.00infobox
LecanemabChemSpidernone1.00infobox
LecanemabDrugBankDB145801.00infobox
LecanemabFormulaC6544H10088N1744O2032S461.00infobox
LecanemabKEGGD116781.00infobox
LecanemabLegal statusCA: ℞-only / Schedule D1.00infobox
LecanemabLegal statusUS: ℞-only1.00infobox
LecanemabLegal statusEU: Rx-only1.00infobox
LecanemabLegal statusRx-only1.00infobox
LecanemabLicense dataUS DailyMed: Lecanemab1.00infobox
LecanemabMedlinePlusa6230041.00infobox
LecanemabMolar mass147181.62 g·mol−11.00infobox
LecanemabOther namesBAN2401, lecanemab-irmb1.00infobox
LecanemabRoutes of administrationIntravenous, subcutaneous1.00infobox
LecanemabSourceHumanized1.00infobox
LecanemabTargetAmyloid beta1.00infobox
LecanemabTrade namesLeqembi1.00infobox
LecanemabTypeWhole antibody1.00infobox
LecanemabUNII12PYH0FTU91.00infobox
Lecanemabis aamyloid beta-directed antibody0.90text
Lecanemabis ahumanized monoclonal antibody consisting of a humanized version of a mouse antibody0.90text

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