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Label-free quantification

Label-free quantification is a method in mass spectrometry that aims to determine the relative amount of proteins in two or more biological samples. Unlike other methods for protein quantification, label-free quantification does not use a stable isotope containing compound to chemically bind to and thus label the protein.

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Overview

Implementation

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Label-free quantification

Nodes17
Edges16
Triples17
Avg. degree1.88
Density0.117647
Components1

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Label-free quantification

Top relations

related to Detecting peptides · 8
Label-free quantification → For, Label-free, MS/MS, MS1, Spectral, The, These, Typically
related to Implementation · 8
Label-free quantification → FTICR, In, Label-free, LC-MS, MS1, Orbitrap, The, ToF
is a · 1
Label-free quantification → method in mass spectrometry that aims to determine the relative amount of proteins in two or more biological samples

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Important terminology

peptide quantification peptides samples label-free biological mass protein different used signals across two thus matching selecting discriminatory proteins may signal

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Label-free quantificationis amethod in mass spectrometry that aims to determine the relative amount of proteins in two or more biological samples0.90text
Label-free quantificationrelated to Detecting peptidesTypically0.60section
Label-free quantificationrelated to Detecting peptidesMS10.60section
Label-free quantificationrelated to Detecting peptidesThese0.60section
Label-free quantificationrelated to Detecting peptidesThe0.60section
Label-free quantificationrelated to Detecting peptidesFor0.60section
Label-free quantificationrelated to Detecting peptidesLabel-free0.60section
Label-free quantificationrelated to Detecting peptidesSpectral0.60section
Label-free quantificationrelated to Detecting peptidesMS/MS0.60section
Label-free quantificationrelated to ImplementationLabel-free0.60section
Label-free quantificationrelated to ImplementationThe0.60section
Label-free quantificationrelated to ImplementationToF0.60section

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