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Immune stimulating complexes (ISCOMs) are spherical open cage-like structures (typically 40 nm in diameter) that are spontaneously formed when mixing together cholesterol, phospholipids and Quillaja saponins under a specific stoichiometry. The complex displays immune stimulating properties and is thus mainly used as a vaccine adjuvant in order to induce…
History & Technology
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immune vaccine response technology saponins 10 iscoms adjuvant doi pmid also iscom-matrix specific quillaja responses 1016 s0264-410x induce stimulating structures
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| an influenza pandemic.ISCOM technology is also able to induce an adaptive immune response in the presence of pre-existing antibodies | instance of | ISCOM-Matrix technology can also be of immense value in a situation when manufacturing capacity is inadequate in the face of an emerging threat | 0.80 | text |
| for example in new-borns who have maternal antibodies.The chemical stability of ISCOM-Matrix is of significant practical value | instance of | ISCOM-Matrix technology can also be of immense value in a situation when manufacturing capacity is inadequate in the face of an emerging threat | 0.80 | text |
| ISCOM | related to Further reading | Martina | 0.60 | section |
| ISCOM | related to Further reading | Byron | 0.60 | section |
| ISCOM | related to Further reading | Van De Bildt | 0.60 | section |
| ISCOM | related to Further reading | Marco | 0.60 | section |
| ISCOM | related to Further reading | Kuiken | 0.60 | section |
| ISCOM | related to Further reading | Thijs | 0.60 | section |
| ISCOM | related to Further reading | Van Amerongen | 0.60 | section |
| ISCOM | related to Further reading | Geert | 0.60 | section |
| ISCOM | related to Further reading | Osterhaus | 0.60 | section |
| ISCOM | related to Further reading | Albert | 0.60 | section |
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