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Iobenguane, or MIBG, is an aralkylguanidine analog of the adrenergic neurotransmitter norepinephrine (noradrenaline), typically used as a radiopharmaceutical. It acts as a blocking agent for adrenergic neurons. When radiolabeled, it can be used in nuclear medicinal diagnostic and therapy techniques as well as in neuroendocrine chemotherapy treatments.
Diagnostic imaging, Usage and mechanism & Thyroid precautions
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mibg used adrenergic norepinephrine imaging diagnostic thyroid therapy 131i tumors clinical 131 adrenal well also cells uptake mechanism 10 pheochromocytomas
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Iobenguane | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Iobenguane | ATC code | V09IX01 (WHO) (123I) V09IX02 (WHO) (131I, diagnostic) V10XA02 (WHO) (131I, therapeutic) | 1.00 | infobox |
| Iobenguane | CAS Number | 80663-95-2 N 77679-27-7 | 1.00 | infobox |
| Iobenguane | CAS Number | 76924-93-1 | 1.00 | infobox |
| Iobenguane | ChEBI | CHEBI:92769 | 1.00 | infobox |
| Iobenguane | ChEMBL | ChEMBL818 N | 1.00 | infobox |
| Iobenguane | ChemSpider | 54847 N | 1.00 | infobox |
| Iobenguane | CompTox Dashboard (EPA) | DTXSID30228311 | 1.00 | infobox |
| Iobenguane | DrugBank | DB06704 Y | 1.00 | infobox |
| Iobenguane | Formula | C8H10IN3 | 1.00 | infobox |
| Iobenguane | KEGG | D04559 | 1.00 | infobox |
| Iobenguane | KEGG | D04560 | 1.00 | infobox |
| Iobenguane | Legal status | US: ℞-only | 1.00 | infobox |
| Iobenguane | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Iobenguane | License data | US DailyMed: Iobenguane | 1.00 | infobox |
| Iobenguane | Molar mass | 275.093 g·mol−1 | 1.00 | infobox |
| Iobenguane | Other names | meta-iodobenzylguanidine mIBG, MIBG | 1.00 | infobox |
| Iobenguane | PubChem CID | 60860 | 1.00 | infobox |
| Iobenguane | PubChem CID | 135326 | 1.00 | infobox |
| Iobenguane | Routes of administration | Intravenous | 1.00 | infobox |
| Iobenguane | Trade names | Adreview, Azedra | 1.00 | infobox |
| Iobenguane | UNII | 35MRW7B4AD | 1.00 | infobox |
| Iobenguane | UNII | P2TH1XYZ84 | 1.00 | infobox |
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