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Atoltivimab/maftivimab/odesivimab

Atoltivimab/maftivimab/odesivimab, sold under the brand name INMAZEB, is a fixed-dose combination of three monoclonal antibodies for the treatment of ebola caused by Zaire ebolavirus. It was developed by Regeneron Pharmaceuticals and contains three human monoclonal antibodies, atoltivimab, maftivimab, and odesivimab-ebgn.

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Key facts & relationships

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AHFS/Drugs.com
Monograph
ATC code
None
Atoltivimab
Monoclonal antibody
CAS Number
2500649-90-9
KEGG
D11922
Legal status
US: ℞-only

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Overview

Medical uses

Pharmacology

History

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Map overview Semantic statistics

Atoltivimab/maftivimab/odesivimab

Nodes37
Edges36
Triples51
Avg. degree1.95
Density0.054054
Components1

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Atoltivimab/maftivimab/odesivimab

Top relations

related to PALM trial · 21
Atoltivimab/maftivimab/odesivimab → Approximately, Congo, Democratic Republic, Despite, DRC, During, Ebola, However, In November, Kivu, Kivu Ebola, Ministry, Once, PALM, Pamoja Tulinde Maisha, Public Health, REGN-EB3, Together Save Lives, WHO MEURI, World Health Organization MEURI
related to Regulatory status · 8
Atoltivimab/maftivimab/odesivimab → European Medicines Agency, INMAZEB, October, Regeneron Pharmaceuticals, REGN-EB3, The, The FDA, Zaire
related to Mechanism of action · 6
Atoltivimab/maftivimab/odesivimab → Bundibugyo, Ebola, The, The Sudan, This, Zaire
related to Contraindications · 2
Atoltivimab/maftivimab/odesivimab → Ebola, People
AHFS/Drugs.com · 1
Atoltivimab/maftivimab/odesivimab → Monograph
ATC code · 1
Atoltivimab/maftivimab/odesivimab → None
Atoltivimab · 1
Atoltivimab/maftivimab/odesivimab → Monoclonal antibody
CAS Number · 1
Atoltivimab/maftivimab/odesivimab → 2500649-90-9
KEGG · 1
Atoltivimab/maftivimab/odesivimab → D11922
Legal status · 1
Atoltivimab/maftivimab/odesivimab → US: ℞-only

Important terminology Word statistics

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Important terminology

atoltivimab maftivimab mab114 ebola regn-eb3 odesivimab trial treatment virus zaire monoclonal outbreak infection drug ebolavirus patients participants antibodies zmapp drc

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Atoltivimab/maftivimab/odesivimabAHFS/Drugs.comMonograph1.00infobox
Atoltivimab/maftivimab/odesivimabATC codeNone1.00infobox
Atoltivimab/maftivimab/odesivimabAtoltivimabMonoclonal antibody1.00infobox
Atoltivimab/maftivimab/odesivimabCAS Number2500649-90-91.00infobox
Atoltivimab/maftivimab/odesivimabKEGGD119221.00infobox
Atoltivimab/maftivimab/odesivimabLegal statusUS: ℞-only1.00infobox
Atoltivimab/maftivimab/odesivimabLicense dataUS DailyMed: Inmazeb1.00infobox
Atoltivimab/maftivimab/odesivimabMaftivimabMonoclonal antibody1.00infobox
Atoltivimab/maftivimab/odesivimabOdesivimabMonoclonal antibody1.00infobox
Atoltivimab/maftivimab/odesivimabOther namesREGN-EB31.00infobox
Atoltivimab/maftivimab/odesivimabRoutes of administrationIntravenous1.00infobox
Atoltivimab/maftivimab/odesivimabTrade namesInmazeb1.00infobox
Atoltivimab/maftivimab/odesivimabis afirst FDA-approved treatment for Zaire ebolavirus0.90text

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