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Immunogenicity

Immunogenicity is the ability of a foreign substance, such as an antigen, to provoke an immune response in the body of a human or other animal. It may be wanted or unwanted:

Characters, Monoclonal antibodies & Antigen characteristics

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Overview

Antigenic immunogenic potency

Antigen characteristics

T cell epitopes

Monoclonal antibodies

Evaluation methods

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Map overview Semantic statistics

Immunogenicity

Nodes50
Edges49
Triples101
Avg. degree1.96
Density0.04
Components1

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Immunogenicity

Top relations

related to Further reading · 48
Immunogenicity → Anne, Annual Review, Antigen-Presenting Molecules, April, Archived, Atlas, Bioengineering, Boca Raton, Cell Recognition, Charles Janeway, Clinical Immunology, CRC Press, Cruse, Disease, Edition, Garland Science, Glycolipids, Health, Immunization, Immunobiology
has method · 17
Immunogenicity → BigMHC, CEDAR, DeepNeo, IEDB, ImmunoStruct, It, Its, MHC, MHCflurry, MHCnuggets, NeoaPred, NetMHCpan, Prime, Rather, SARS-CoV-2, They, Transformer
related to T cell epitopes · 13
Immunogenicity → ADAs, APCs, Because, Cell, Dendritic Cell, Epitopes, Eprex, HLA, ITP, Likewise, MHC, This, When
related to In silico screening · 7
Immunogenicity → By, HLA, Immunoinformatics, In, One, T-cell, These
related to Monoclonal antibodies · 7
Immunogenicity → Although, Consequently, Genetic, IgE, Rheumatoid, Several, Therapeutic
is a · 3
Immunogenicity → ability of a foreign substance, binding strength of T cell epitopes to major histocompatibility complexes, central aspect of vaccine development.Unwanted immunogenicity is an immune response by an organism against a therapeutic antigen
related to Antigen characteristics · 2
Immunogenicity → Molecules, Phylogenetic

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Important terminology

antigen cell immune response protein immunogenic unwanted antibodies vaccines may adaptive induce epitopes epitope mabs therapeutics antigenicity proteins mhc peptide

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Immunogenicityis aability of a foreign substance0.90text
Immunogenicityis acentral aspect of vaccine development.Unwanted immunogenicity is an immune response by an organism against a therapeutic antigen0.90text
Immunogenicityis abinding strength of T cell epitopes to major histocompatibility complexes0.90text
a protein or polysaccharide to increase immunogenic potency so that they can evoke an immune response.Proteinsinstance ofthey may require conjugation with an epitope0.80text
few polysaccharides have immunogenic propertiesinstance ofthey may require conjugation with an epitope0.80text
which allows them to induce humoral immune responses.Proteinsinstance ofthey may require conjugation with an epitope0.80text
some lipids/glycolypids can serve as immunogens for cell-mediated immunity.Proteins are significantly more immunogenic than polysaccharidesinstance ofthey may require conjugation with an epitope0.80text
Immunogenicityhas methodPrime0.60section
Immunogenicityhas methodNetMHCpan0.60section
Immunogenicityhas methodMHCnuggets0.60section
Immunogenicityhas methodMHCflurry0.60section
Immunogenicityhas methodDeepNeo0.60section

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