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HSD3B2: Standards & Products

HSD3B2 is a human gene that encodes for 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase type II or hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. It is expressed principally in steroidogenic tissues and is essential for steroid hormone production. A notable exception is the placenta, where HSD3B1 is critical…

Language: English [EN]
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HSD3B2 topic overview

The analysis highlights Standards and Products as prominent areas in the source structure around HSD3B2.

Related topics
7
Source areas
1
Connected nodes
8
Extracted relationships
87
Related term clusters
9
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 7 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.1.1.145
↗
5.3.3.1
↗
Aliases
HSD3B2, HSD3B, HSDB, SDR11E2, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
Band
1p12 · 3 F2.2|3 42.89 cM
Bgee
right adrenal gland · right adrenal cortex · left adrenal gland · left adrenal cortex · testicle
BioGPS
More reference expression data

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HSD3B2
6Gene · 3-beta-HSD · Steroid hormone

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How HSD3B2 connects Entity context

The extracted context around HSD3B2 shows recurring relationship patterns in the source. For example, HSD3B2 → 3-beta-hydroxy-delta5-steroid dehydrogenase activity, androgen biosynthetic process, C21-steroid hormone metabolic process, catalytic activity, cholesterol dehydrogenase activity, endoplasmic reticulum, endoplasmic reticulum membrane, glucocorticoid biosynthetic process, hippocampus development, integral component of membrane, intracellular membrane-bounded organelle, isomerase activity, membrane, metabolism, mineralocorticoid biosynthetic process, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membranes, mitochondrion, oxidoreductase activity Another extracted example is HSD3B2 → adrenal gland, adrenal medulla, cumulus cell, embryo, Gonadal ridge, left adrenal cortex, left adrenal gland, mucosa of transverse colon, oocyte, ovary, placenta, renal pelvis, right adrenal cortex, right adrenal gland, right coronary artery, secondary oocyte, spermatocyte, testicle, urethra. Use these groups to spot repeated connection types before inspecting the individual relationships.

HSD3B2

Top relations

Gene ontology · 25
HSD3B2 → 3-beta-hydroxy-delta5-steroid dehydrogenase activity, androgen biosynthetic process, C21-steroid hormone metabolic process, catalytic activity, cholesterol dehydrogenase activity, endoplasmic reticulum, endoplasmic reticulum membrane, glucocorticoid biosynthetic process, hippocampus development, integral component of membrane, intracellular membrane-bounded organelle, isomerase activity, membrane, metabolism, mineralocorticoid biosynthetic process, mitochondrial inner membrane, mitochondrial intermembrane space, mitochondrial membranes, mitochondrion, oxidoreductase activity
Bgee · 19
HSD3B2 → adrenal gland, adrenal medulla, cumulus cell, embryo, Gonadal ridge, left adrenal cortex, left adrenal gland, mucosa of transverse colon, oocyte, ovary, placenta, renal pelvis, right adrenal cortex, right adrenal gland, right coronary artery, secondary oocyte, spermatocyte, testicle, urethra
RNA expression pattern · 19
HSD3B2 → adrenal gland, adrenal medulla, cumulus cell, embryo, Gonadal ridge, left adrenal cortex, left adrenal gland, mucosa of transverse colon, oocyte, ovary, placenta, renal pelvis, right adrenal cortex, right adrenal gland, right coronary artery, secondary oocyte, spermatocyte, testicle, urethra
Band · 2
HSD3B2 → 1p12, 3 F2.2|3 42.89 cM
Chr. · 2
HSD3B2 → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
HSD3B2 → 119,423,035 bp, 98,767,110 bp
1.1.1.145 · 1
HSD3B2 → ↗
5.3.3.1 · 1
HSD3B2 → ↗
Aliases · 1
HSD3B2 → HSD3B2, HSD3B, HSDB, SDR11E2, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
BioGPS · 1
HSD3B2 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human gene bp chr band dehydrogenase steroid chromosome delta-isomerase location production placenta mouse isomerase hydroxy-delta-5-steroid beta- expressed hormone adrenal activity

HSD3B2 relationships Subject–Predicate–Object triples

TTTA extracted 87 structured relationships around HSD3B2. Examples in this analysis include HSD3B2 → 1.1.1.145 → ↗ and HSD3B2 → Aliases → HSD3B2, HSD3B, HSDB, SDR11E2, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
HSD3B21.1.1.145↗1.00infobox
HSD3B25.3.3.1↗1.00infobox
HSD3B2AliasesHSD3B2, HSD3B, HSDB, SDR11E2, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 21.00infobox
HSD3B2Band1p121.00infobox
HSD3B2Band3 F2.2|3 42.89 cM1.00infobox
HSD3B2Bgeeright adrenal gland1.00infobox
HSD3B2Bgeeright adrenal cortex1.00infobox
HSD3B2Bgeeleft adrenal gland1.00infobox
HSD3B2Bgeeleft adrenal cortex1.00infobox
HSD3B2Bgeetesticle1.00infobox
HSD3B2Bgeeoocyte1.00infobox
HSD3B2Bgeemucosa of transverse colon1.00infobox
HSD3B2Bgeeplacenta1.00infobox
HSD3B2Bgeesecondary oocyte1.00infobox
HSD3B2Bgeeright coronary artery1.00infobox
HSD3B2Bgeeadrenal gland1.00infobox
HSD3B2Bgeecumulus cell1.00infobox
HSD3B2BgeeGonadal ridge1.00infobox
HSD3B2Bgeeadrenal medulla1.00infobox
HSD3B2Bgeeovary1.00infobox
HSD3B2Bgeeurethra1.00infobox
HSD3B2Bgeespermatocyte1.00infobox
HSD3B2Bgeerenal pelvis1.00infobox
HSD3B2Bgeeembryo1.00infobox
HSD3B2BioGPSMore reference expression data1.00infobox
HSD3B2Chr.Chromosome 1 (human)1.00infobox
HSD3B2Chr.Chromosome 3 (mouse)1.00infobox
HSD3B2DatabasesNCBI: entry; OMA: entry1.00infobox
HSD3B2End119,423,035 bp1.00infobox
HSD3B2End98,767,110 bp1.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around HSD3B2 bring nearby vocabulary together. In this analysis, examples include Dehydrogenase, Gene and Delta-isomerase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • HSD3B2
    • Dehydrogenase
    • Gene
    • Delta-isomerase
    • Steroid
    • Activity
    • Adrenal
    • Beta-
    • Human
    • Hydroxy-delta-5-steroid
    • Isomerase
    • Location
    • Chromosome
  • hsd3b2
    • Dehydrogenase
    • Gene
    • Delta-isomerase
    • Steroid
    • Activity
    • Adrenal
    • Beta-
    • Human
    • Hydroxy-delta-5-steroid
    • Isomerase
    • Location
    • Chromosome
  • gene
    • Dehydrogenase
    • Hsd3b2
    • Human
    • Delta-isomerase
    • Location
    • Chromosome
    • Steroid
    • Bp
    • Chr
    • Activity
    • Adrenal
    • Beta-
  • 3beta-hydroxysteroid dehydrogenase/delta(5)-delta(4)isomerase
    • -delta
    • 3beta-hydroxysteroid
    • Delta
    • Encodes
    • Hsd3b2
    • Ii
    • Type
    • Gene
    • Delta-isomerase
    • Steroid
    • Activity
    • Adrenal
  • congenital adrenal hyperplasia due to 3 beta-hydroxysteroid dehydrogenase deficiency
    • Hsd3b2
    • Gene
    • Delta-isomerase
    • Steroid
    • Activity
    • Adrenal
    • Beta-
    • Dehydrogenase
    • Human
    • Hydroxy-delta-5-steroid
    • Isomerase
    • Location
  • steroid hormone
    • Activity
    • Expressed
    • Hormone
    • Principally
    • Steroid
    • Steroidogenic
    • Location
    • Adrenal
    • Chromosome
    • End
    • F2
    • Isomerase
  • placenta
    • Progesterone
    • Activity
    • Adrenal
    • End
    • F2
    • Mouse
    • Production
    • Location
    • Band
    • Chromosome
    • Steroid
    • Bp
  • hsd3b1
    • Progesterone
    • Placenta
    • Production

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the HSD3B2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

HSD3B2

Nodes9
Edges8
Triples87
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around HSD3B2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — HSD3B2 · EN edition · Analysis: TopicsToTalkAbout

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