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High mobility group protein B4 is a transcription factor that in humans is encoded by the HMGB4 gene.
The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around HMGB4.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around HMGB4 shows recurring relationship patterns in the source. For example, HMGB4 → activation of innate immune response, cell chemotaxis, chromatin remodeling, chromosome, cytoplasm, developmental process, DNA binding, DNA binding, bending, DNA recombination, nucleus, positive regulation of autophagy, positive regulation of ERK1 and ERK2 cascade, positive regulation of innate immune response, positive regulation of interleukin-6 production, positive regulation of NIK/NF-kappaB signaling, positive regulation of transcription by RNA polymerase II, positive regulation of tumor necrosis factor production, protein binding, regulation of signaling receptor activity, regulation of transcription by RNA polymerase II Another extracted example is HMGB4 → canal of the cervix, caput epididymis, central gray substance of midbrain, ectocervix, hypothalamus, islet of Langerhans, left testis, muscle tissue, pancreas, right coronary artery, right testis, right uterine tube, seminiferous tubule, skeletal muscle tissue, sperm, spermatid, spermatocyte, striated muscle tissue, tail of epididymis, testicle. Use these groups to spot repeated connection types before inspecting the individual relationships.
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bp chr human chromosome band gene group location mouse high mobility protein transcription factor 864 791 end 33 d2 154
TTTA extracted 81 structured relationships around HMGB4. Examples in this analysis include HMGB4 → Aliases → HMGB4, dJ1007G16.5, high mobility group box 4 and HMGB4 → Band → 1p35.1. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| HMGB4 | Aliases | HMGB4, dJ1007G16.5, high mobility group box 4 | 1.00 | infobox |
| HMGB4 | Band | 1p35.1 | 1.00 | infobox |
| HMGB4 | Band | 4|4 D2.2 | 1.00 | infobox |
| HMGB4 | Bgee | right testis | 1.00 | infobox |
| HMGB4 | Bgee | left testis | 1.00 | infobox |
| HMGB4 | Bgee | sperm | 1.00 | infobox |
| HMGB4 | Bgee | testicle | 1.00 | infobox |
| HMGB4 | Bgee | tail of epididymis | 1.00 | infobox |
| HMGB4 | Bgee | right coronary artery | 1.00 | infobox |
| HMGB4 | Bgee | caput epididymis | 1.00 | infobox |
| HMGB4 | Bgee | ectocervix | 1.00 | infobox |
| HMGB4 | Bgee | right uterine tube | 1.00 | infobox |
| HMGB4 | Bgee | canal of the cervix | 1.00 | infobox |
| HMGB4 | Bgee | seminiferous tubule | 1.00 | infobox |
| HMGB4 | Bgee | spermatid | 1.00 | infobox |
| HMGB4 | Bgee | spermatocyte | 1.00 | infobox |
| HMGB4 | Bgee | muscle tissue | 1.00 | infobox |
| HMGB4 | Bgee | central gray substance of midbrain | 1.00 | infobox |
| HMGB4 | Bgee | striated muscle tissue | 1.00 | infobox |
| HMGB4 | Bgee | pancreas | 1.00 | infobox |
| HMGB4 | Bgee | skeletal muscle tissue | 1.00 | infobox |
| HMGB4 | Bgee | islet of Langerhans | 1.00 | infobox |
| HMGB4 | Bgee | hypothalamus | 1.00 | infobox |
| HMGB4 | BioGPS | n/a | 1.00 | infobox |
| HMGB4 | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| HMGB4 | Chr. | Chromosome 4 (mouse) | 1.00 | infobox |
| HMGB4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| HMGB4 | End | 33,864,791 bp | 1.00 | infobox |
| HMGB4 | End | 128,154,750 bp | 1.00 | infobox |
| HMGB4 | Ensembl | ENSG00000176256 | 1.00 | infobox |
The concept neighborhoods around HMGB4 bring nearby vocabulary together. In this analysis, examples include Mobility, Protein and Transcription. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the HMGB4 map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around HMGB4 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — HMGB4 · EN edition · Analysis: TopicsToTalkAbout
