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HEXB

Beta-hexosaminidase subunit beta is an enzyme that in humans is encoded by the HEXB gene.

Measurement, Function & Structure

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Function

7 related topics

Structure

3 related topics

Interactions

1 related topics

Overview

3 related topics

Key facts & relationships

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3.2.1.52
Aliases
HEXB, ENC-1AS, HEL-248, HEL-S-111, hexosaminidase subunit beta
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1NOU, 1NOW, 1NP0, 1O7A, 2GJX, 2GK1, 3LMY, 5BRO
Band
5q13.3 · 13 D1|13 50.66 cM
Bgee
placenta · stromal cell of endometrium · Achilles tendon · decidua · monocyte
BioGPS
More reference expression data

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Structure

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Map overview Semantic statistics

HEXB

Nodes19
Edges18
Triples125
Avg. degree1.89
Density0.105263
Components1

How this topic connects Entity context

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HEXB

Top relations

Gene ontology · 47
HEXB → acetylglucosaminyltransferase activity, acrosomal vesicle, astrocyte cell migration, azurophil granule, azurophil granule lumen, beta-N-acetylhexosaminidase activity, carbohydrate metabolic process, cellular calcium ion homeostasis, chondroitin sulfate catabolic process, extracellular exosome, extracellular region, extracellular space, ganglioside catabolic process, glycosaminoglycan metabolic process, glycosphingolipid metabolic process, hearing, hyaluronan catabolic process, hydrolase activity, hydrolase activity, acting on glycosyl bonds, hydrolase activity, hydrolyzing O-glycosyl compounds
Bgee · 20
HEXB → Achilles tendon, beta cell, body of femur, calvaria, ciliary body, corpus epididymis, decidua, epithelium of small intestine, globus pallidus, islet of Langerhans, lacrimal gland, left colon, monocyte, parotid gland, placenta, stromal cell of endometrium, submandibular gland, synovial joint, tendon of biceps brachii, transitional epithelium of urinary bladder
RNA expression pattern · 20
HEXB → Achilles tendon, beta cell, body of femur, calvaria, ciliary body, corpus epididymis, decidua, epithelium of small intestine, globus pallidus, islet of Langerhans, lacrimal gland, left colon, monocyte, parotid gland, placenta, stromal cell of endometrium, submandibular gland, synovial joint, tendon of biceps brachii, transitional epithelium of urinary bladder
related to Clinical significance · 7
HEXB → Genetic, GM2, Hex, Intracerebroventricular, Patients, Sandhoff, Therapeutic
related to Function · 4
HEXB → GalNAc, GlcNAc, GM2, Inability
Band · 2
HEXB → 13 D1|13 50.66 cM, 5q13.3
Chr. · 2
HEXB → Chromosome 13 (mouse), Chromosome 5 (human)
End · 2
HEXB → 74,722,647 bp, 97,334,865 bp
3.2.1.52 · 1
HEXB → ↗
Aliases · 1
HEXB → HEXB, ENC-1AS, HEL-248, HEL-S-111, hexosaminidase subunit beta

Important terminology Word statistics

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Important terminology

beta gene subunit ganglioside bp beta-hexosaminidase chr chromosome human band gm2 enzyme alpha location protein sandhoff subunits lead lysosomal glycosyl

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HEXB3.2.1.521.00infobox
HEXBAliasesHEXB, ENC-1AS, HEL-248, HEL-S-111, hexosaminidase subunit beta1.00infobox
HEXBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1NOU, 1NOW, 1NP0, 1O7A, 2GJX, 2GK1, 3LMY, 5BRO1.00infobox
HEXBBand5q13.31.00infobox
HEXBBand13 D1|13 50.66 cM1.00infobox
HEXBBgeeplacenta1.00infobox
HEXBBgeestromal cell of endometrium1.00infobox
HEXBBgeeAchilles tendon1.00infobox
HEXBBgeedecidua1.00infobox
HEXBBgeemonocyte1.00infobox
HEXBBgeeislet of Langerhans1.00infobox
HEXBBgeebeta cell1.00infobox
HEXBBgeetendon of biceps brachii1.00infobox
HEXBBgeecorpus epididymis1.00infobox
HEXBBgeesynovial joint1.00infobox
HEXBBgeelacrimal gland1.00infobox
HEXBBgeeepithelium of small intestine1.00infobox
HEXBBgeesubmandibular gland1.00infobox
HEXBBgeeleft colon1.00infobox
HEXBBgeetransitional epithelium of urinary bladder1.00infobox
HEXBBgeecalvaria1.00infobox
HEXBBgeeparotid gland1.00infobox
HEXBBgeebody of femur1.00infobox
HEXBBgeeciliary body1.00infobox
HEXBBgeeglobus pallidus1.00infobox
HEXBBioGPSMore reference expression data1.00infobox
HEXBChr.Chromosome 5 (human)1.00infobox
HEXBChr.Chromosome 13 (mouse)1.00infobox
HEXBDatabasesNCBI: entry; OMA: entry1.00infobox
HEXBEnd74,722,647 bp1.00infobox

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