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Hexamethonium is a non-depolarising ganglionic blocker, a neuronal nicotinic (nAChR) receptor antagonist that acts in autonomic ganglia by binding mostly in or on the nAChR receptor, and not the acetylcholine binding site itself. It does not have any effect on the muscarinic acetylcholine receptors (mAChR) located on target organs of the parasympathetic…
Applications, Pharmacology & Uses
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acetylcholine nicotinic receptors sympathetic ganglia nachr neuronal parasympathetic nervous system antagonist acts autonomic binding site muscarinic normal machr systems citation
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Hexamethonium | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Hexamethonium | CAS Number | 60-26-4 N | 1.00 | infobox |
| Hexamethonium | ChEMBL | ChEMBL105608 N | 1.00 | infobox |
| Hexamethonium | ChemSpider | 3478 Y | 1.00 | infobox |
| Hexamethonium | CompTox Dashboard (EPA) | DTXSID9045053 | 1.00 | infobox |
| Hexamethonium | DrugBank | DB08960 N | 1.00 | infobox |
| Hexamethonium | Formula | C12H30N2 | 1.00 | infobox |
| Hexamethonium | IUPHAR/BPS | 3963 | 1.00 | infobox |
| Hexamethonium | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Hexamethonium | Molar mass | 202.386 g·mol−1 | 1.00 | infobox |
| Hexamethonium | Pregnancy category | D | 1.00 | infobox |
| Hexamethonium | PubChem CID | 3604 | 1.00 | infobox |
| Hexamethonium | UNII | 3C9PSP36Z2 | 1.00 | infobox |
| Hexamethonium | is a | non-depolarising ganglionic blocker | 0.90 | text |
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