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Histone H3.3 is a protein that in humans is encoded by the H3F3A and H3F3B genes. It plays an essential role in maintaining genome integrity during mammalian development.
The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around H3F3A.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around H3F3A shows recurring relationship patterns in the source. For example, H3F3A → Barr body, blood coagulation, brain development, cell population proliferation, chromosome, DNA binding, embryo implantation, epigenetic maintenance of chromatin in transcription-competent conformation, extracellular exosome, extracellular region, histone binding, male gonad development, multicellular organism growth, muscle cell differentiation, negative regulation of chromosome condensation, negative regulation of gene expression, epigenetic, nuclear chromosome, nucleoplasm, nucleosomal DNA binding, nucleosome Another extracted example is H3F3A → appendix, blood, bone marrow, corpus callosum, endometrium, epiblast, gallbladder, ganglionic eminence, granulocyte, ileum, lip, mesencephalon, monocyte, neural tube, rectum, thymus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
histone bp h3 also chr human chromosome band gene protein dna h3f3b genes location encoded histones nucleosomes lys27met dipg nucleosome
TTTA extracted 100 structured relationships around H3F3A. Examples in this analysis include H3F3A → Aliases → H3-3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A, H3.3 histone A, H3F3A, H3-3B and H3F3A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I,…. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| H3F3A | Aliases | H3-3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A, H3.3 histone A, H3F3A, H3-3B | 1.00 | infobox |
| H3F3A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I,… | 1.00 | infobox |
| H3F3A | Band | 1q42.12 | 1.00 | infobox |
| H3F3A | Band | 1|1 H4 | 1.00 | infobox |
| H3F3A | Bgee | ganglionic eminence | 1.00 | infobox |
| H3F3A | Bgee | ventricular zone | 1.00 | infobox |
| H3F3A | Bgee | monocyte | 1.00 | infobox |
| H3F3A | Bgee | blood | 1.00 | infobox |
| H3F3A | Bgee | endometrium | 1.00 | infobox |
| H3F3A | Bgee | rectum | 1.00 | infobox |
| H3F3A | Bgee | corpus callosum | 1.00 | infobox |
| H3F3A | Bgee | granulocyte | 1.00 | infobox |
| H3F3A | Bgee | appendix | 1.00 | infobox |
| H3F3A | Bgee | gallbladder | 1.00 | infobox |
| H3F3A | Bgee | neural tube | 1.00 | infobox |
| H3F3A | Bgee | mesencephalon | 1.00 | infobox |
| H3F3A | Bgee | thymus | 1.00 | infobox |
| H3F3A | Bgee | lip | 1.00 | infobox |
| H3F3A | Bgee | bone marrow | 1.00 | infobox |
| H3F3A | Bgee | ileum | 1.00 | infobox |
| H3F3A | Bgee | epiblast | 1.00 | infobox |
| H3F3A | BioGPS | n/a | 1.00 | infobox |
| H3F3A | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| H3F3A | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| H3F3A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| H3F3A | End | 226,073,212 bp | 1.00 | infobox |
| H3F3A | End | 180,641,508 bp | 1.00 | infobox |
| H3F3A | Ensembl | ENSG00000163041 | 1.00 | infobox |
| H3F3A | Entrez | 3020 | 1.00 | infobox |
| H3F3A | External IDs | OMIM: 601128; MGI: 1097686; GeneCards: H3-3A | 1.00 | infobox |
The concept neighborhoods around H3F3A bring nearby vocabulary together. In this analysis, examples include Also, H3f3b and Histone. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the H3F3A map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around H3F3A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — H3F3A · EN edition · Analysis: TopicsToTalkAbout