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H3F3A

Histone H3.3 is a protein that in humans is encoded by the H3F3A and H3F3B genes. It plays an essential role in maintaining genome integrity during mammalian development.

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Aliases
H3-3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A, H3.3 histone A, H3F3A, H3-3B
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I,…
Band
1q42.12 · 1|1 H4
Bgee
ganglionic eminence · ventricular zone · monocyte · blood · endometrium
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

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Map overview Semantic statistics

H3F3A

Nodes12
Edges11
Triples100
Avg. degree1.83
Density0.166667
Components1

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H3F3A

Top relations

Gene ontology · 43
H3F3A → Barr body, blood coagulation, brain development, cell population proliferation, chromosome, DNA binding, embryo implantation, epigenetic maintenance of chromatin in transcription-competent conformation, extracellular exosome, extracellular region, histone binding, male gonad development, multicellular organism growth, muscle cell differentiation, negative regulation of chromosome condensation, negative regulation of gene expression, epigenetic, nuclear chromosome, nucleoplasm, nucleosomal DNA binding, nucleosome
Bgee · 17
H3F3A → appendix, blood, bone marrow, corpus callosum, endometrium, epiblast, gallbladder, ganglionic eminence, granulocyte, ileum, lip, mesencephalon, monocyte, neural tube, rectum, thymus, ventricular zone
RNA expression pattern · 17
H3F3A → appendix, blood, bone marrow, corpus callosum, endometrium, epiblast, gallbladder, ganglionic eminence, granulocyte, ileum, lip, mesencephalon, monocyte, neural tube, rectum, thymus, ventricular zone
Band · 2
H3F3A → 1q42.12, 1|1 H4
Chr. · 2
H3F3A → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
H3F3A → 180,641,508 bp, 226,073,212 bp
Aliases · 1
H3F3A → H3-3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A, H3.3 histone A, H3F3A, H3-3B
Available structures · 1
H3F3A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I,…
BioGPS · 1
H3F3A → n/a
Databases · 1
H3F3A → NCBI: entry; OMA: entry

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Important terminology

histone bp h3 also chr human chromosome band gene protein dna h3f3b genes location encoded histones nucleosomes lys27met dipg nucleosome

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
H3F3AAliasesH3-3A, H3.3A, H3F3, H3 histone, family 3A, H3 histone family member 3A, H3.3 histone A, H3F3A, H3-3B1.00infobox
H3F3AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4H9O, 5BNX, 3JVK, 5DWQ, 4L58, 4TMP, 5DX0, 4H9S, 4W5A, 3AV2, 3WTP, 4HGA, 4GUS, 4GY5, 3MUK, 3QLC, 4H9Q, 4N4I,…1.00infobox
H3F3ABand1q42.121.00infobox
H3F3ABand1|1 H41.00infobox
H3F3ABgeeganglionic eminence1.00infobox
H3F3ABgeeventricular zone1.00infobox
H3F3ABgeemonocyte1.00infobox
H3F3ABgeeblood1.00infobox
H3F3ABgeeendometrium1.00infobox
H3F3ABgeerectum1.00infobox
H3F3ABgeecorpus callosum1.00infobox
H3F3ABgeegranulocyte1.00infobox
H3F3ABgeeappendix1.00infobox
H3F3ABgeegallbladder1.00infobox
H3F3ABgeeneural tube1.00infobox
H3F3ABgeemesencephalon1.00infobox
H3F3ABgeethymus1.00infobox
H3F3ABgeelip1.00infobox
H3F3ABgeebone marrow1.00infobox
H3F3ABgeeileum1.00infobox
H3F3ABgeeepiblast1.00infobox
H3F3ABioGPSn/a1.00infobox
H3F3AChr.Chromosome 1 (human)1.00infobox
H3F3AChr.Chromosome 1 (mouse)1.00infobox
H3F3ADatabasesNCBI: entry; OMA: entry1.00infobox
H3F3AEnd226,073,212 bp1.00infobox
H3F3AEnd180,641,508 bp1.00infobox
H3F3AEnsemblENSG000001630411.00infobox
H3F3AEntrez30201.00infobox
H3F3AExternal IDsOMIM: 601128; MGI: 1097686; GeneCards: H3-3A1.00infobox

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