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Guselkumab: History, Community, Culture & Applications

Guselkumab (/ɡjuˈsɛlkjumæb/ gew-SEL-kew-mab; sold under the brand name Tremfya) is a human monoclonal antibody against interleukin-23 used for the treatment of plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn's disease.

Language: English [EN]
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Guselkumab topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Guselkumab.

Related topics
19
Source areas
6
Connected nodes
25
Extracted relationships
55
Concept neighborhoods
16
Bridge connections
25

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics
Research · 4 topics
Adverse effects · 3 topics
History · 3 topics
Society and culture · 2 topics
Medical uses · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AHFS/Drugs.com
Monograph
ATC code
L04AC16 (WHO)
CAS Number
1350289-85-8
ChemSpider
none
DrugBank
DB11834
Formula
C6402H9864N1676O1994S42

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Guselkumab connects Entity context

The extracted context around Guselkumab shows recurring relationship patterns in the source. For example, Guselkumab → At, ClinicalTrials, Humira, IDs, III, NCT02207231, NCT02207244, PASI, Preliminary, Stelara, The, VOYAGE Another extracted example is Guselkumab → Biologics License Application, BLA, Drug Administration, FDA, In November, Janssen, Janssen Pharmaceuticals, US Food. Use these groups to spot repeated connection types before inspecting the individual relationships.

Guselkumab

Top relations

related to Research · 12
Guselkumab → At, ClinicalTrials, Humira, IDs, III, NCT02207231, NCT02207244, PASI, Preliminary, Stelara, The, VOYAGE
related to history · 8
Guselkumab → Biologics License Application, BLA, Drug Administration, FDA, In November, Janssen, Janssen Pharmaceuticals, US Food
related to Legal status · 7
Guselkumab → Drug Administration, FDA, Health Canada, In July, In November, In September, US Food
Legal status · 5
Guselkumab → AU: S4 (Prescription only), CA: Rx-only, Schedule D, EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Names · 2
Guselkumab → CNTO-1959, During
AHFS/Drugs.com · 1
Guselkumab → Monograph
ATC code · 1
Guselkumab → L04AC16 (WHO)
CAS Number · 1
Guselkumab → 1350289-85-8
ChemSpider · 1
Guselkumab → none
DrugBank · 1
Guselkumab → DB11834

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

treatment approved psoriatic arthritis plaque psoriasis ulcerative colitis tremfya us gew-sel-kew-mab fda patients crohn's disease adalimumab ustekinumab human administration ɡjuˈsɛlkjumæb

Guselkumab relationships Subject–Predicate–Object triples

TTTA extracted 55 structured relationships around Guselkumab. Examples in this analysis include Guselkumab → AHFS/Drugs.com → Monograph and Guselkumab → ATC code → L04AC16 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GuselkumabAHFS/Drugs.comMonograph1.00infobox
GuselkumabATC codeL04AC16 (WHO)1.00infobox
GuselkumabCAS Number1350289-85-81.00infobox
GuselkumabChemSpidernone1.00infobox
GuselkumabDrugBankDB118341.00infobox
GuselkumabFormulaC6402H9864N1676O1994S421.00infobox
GuselkumabKEGGD104381.00infobox
GuselkumabLegal statusAU: S4 (Prescription only)1.00infobox
GuselkumabLegal statusCA: Rx-only, Schedule D1.00infobox
GuselkumabLegal statusUK: POM (Prescription only)1.00infobox
GuselkumabLegal statusUS: ℞-only1.00infobox
GuselkumabLegal statusEU: Rx-only1.00infobox
GuselkumabLicense dataUS DailyMed: Guselkumab1.00infobox
GuselkumabMedlinePlusa6170361.00infobox
GuselkumabMolar mass143561.59 g·mol−11.00infobox
GuselkumabPregnancy categoryAU: B11.00infobox
GuselkumabPronunciation/ɡjuˈsɛlkjumæb/ gew-SEL-kew-mab1.00infobox
GuselkumabRoutes of administrationSubcutaneous, intravenous1.00infobox
GuselkumabSourceHuman1.00infobox
GuselkumabTargetIL231.00infobox
GuselkumabTrade namesTremfya1.00infobox
GuselkumabTypeWhole antibody1.00infobox
GuselkumabUNII089658A12D1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Guselkumab bring nearby vocabulary together. In this analysis, examples include Approved, Treatment and Colitis. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Guselkumab
    • Approved
    • Treatment
    • Colitis
    • Fda
    • Plaque
    • Psoriasis
    • Ulcerative
    • Arthritis
    • Psoriatic
    • Adalimumab
    • Administration
    • Crohn's
  • guselkumab
    • Approved
    • Treatment
    • Colitis
    • Fda
    • Plaque
    • Psoriasis
    • Ulcerative
    • Arthritis
    • Psoriatic
    • Adalimumab
    • Administration
    • Crohn's
  • monoclonal antibody
    • Gew-sel-kew-mab
    • Human
    • Ɡjuˈsɛlkjumæb
    • Crohn's
    • Disease
    • Tremfya
    • Colitis
    • Interleukin-23
    • Plaque
    • Psoriasis
    • Ulcerative
    • Arthritis
  • psoriatic arthritis
    • Psoriatic
    • Gew-sel-kew-mab
    • Human
    • Treat
    • Ɡjuˈsɛlkjumæb
    • Crohn's
    • Disease
    • Treatment
    • Tremfya
    • Colitis
    • Plaque
    • Psoriasis
  • ulcerative colitis
    • Ulcerative
    • Crohn's
    • Disease
    • Gew-sel-kew-mab
    • Human
    • Uk
    • Ɡjuˈsɛlkjumæb
    • Tremfya
    • Plaque
    • Psoriasis
    • Psoriatic
    • Approved
  • food and drug administration
    • Us
    • License
    • Fda
    • Plaque
    • Psoriasis
    • Antibody
    • Gew-sel-kew-mab
    • Human
    • Indicated
    • Legal
    • Mg
    • Names
  • crohn's disease
    • Disease
    • Ulcerative
    • Gew-sel-kew-mab
    • Human
    • Uk
    • Ɡjuˈsɛlkjumæb
    • Tremfya
    • Plaque
    • Psoriasis
    • Interleukin-23
    • Psoriatic
    • Indicated
  • plaque psoriasis
    • Psoriasis
    • Ɡjuˈsɛlkjumæb
    • Administration
    • Tremfya
    • Treatment
    • Ulcerative
    • Us
    • Psoriatic
    • Approved
    • Indicated
    • Legal
    • License

Connections between topic areas Semantic bridges

For Guselkumab, one of the stronger structural bridges in this analysis connects Guselkumab with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GuselkumabOverview · splits 19 ⟂ 7
GuselkumabResearch · splits 21 ⟂ 5
GuselkumabAdverse effects · splits 22 ⟂ 4
GuselkumabHistory · splits 22 ⟂ 4
GuselkumabSociety and culture · splits 23 ⟂ 3

Map overview Semantic statistics

Guselkumab

Nodes26
Edges25
Triples55
Avg. degree1.92
Density0.076923
Components1

Source & methodology

TTTA analyzes the structure around Guselkumab to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Guselkumab · EN edition · Analysis: TopicsToTalkAbout

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