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Griffithsin: Standards & Overview

Griffithsin is a protein isolated from the red algae Griffithsia. It has a 121-amino acid sequence which exhibits a Jacalin-like lectin fold. Several structures of this protein have been solved by X-ray crystallography and deposited in the PDB. It has been shown in vitro to be a highly potent HIV entry inhibitor. It is currently being investigated as a…

Language: English [EN]
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Griffithsin topic overview

The analysis highlights Standards and Overview as prominent areas in the source structure around Griffithsin.

Related topics
18
Source areas
1
Connected nodes
19
Extracted relationships
9
Related term clusters
19
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 18 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
Organism
Griffithsia sp. (Red alga)
Orthologs
OMA: entry
PDB
3ll2More structures
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Griffithsin connects Entity context

The extracted context around Griffithsin shows recurring relationship patterns in the source. For example, Griffithsin → InterPro Another extracted example is Griffithsin → Griffithsia sp. (Red alga). Use these groups to spot repeated connection types before inspecting the individual relationships.

Griffithsin

Top relations

Domains · 1
Griffithsin → InterPro
Organism · 1
Griffithsin → Griffithsia sp. (Red alga)
Orthologs · 1
Griffithsin → OMA: entry
PDB · 1
Griffithsin → 3ll2More structures
Search for · 1
Griffithsin → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Griffithsin → Swiss-model
Symbol · 1
Griffithsin → GRFT
UniProt · 1
Griffithsin → P84801
is a · 1
Griffithsin → protein isolated from the red algae Griffithsia

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

hiv pdb entry griffithsia red protein microbicide glycoproteins shown vitro bind virus 3ll2 structures carbohydrate sp alga coronavirus sars ebolavirus

Griffithsin relationships Subject–Predicate–Object triples

TTTA extracted 9 structured relationships around Griffithsin. Examples in this analysis include Griffithsin → Domains → InterPro and Griffithsin → Organism → Griffithsia sp. (Red alga). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GriffithsinDomainsInterPro1.00infobox
GriffithsinOrganismGriffithsia sp. (Red alga)1.00infobox
GriffithsinOrthologsOMA: entry1.00infobox
GriffithsinPDB3ll2More structures1.00infobox
GriffithsinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
GriffithsinStructuresSwiss-model1.00infobox
GriffithsinSymbolGRFT1.00infobox
GriffithsinUniProtP848011.00infobox
Griffithsinis aprotein isolated from the red algae Griffithsia0.90text

Related concept clusters Related term clusters

The concept neighborhoods around Griffithsin bring nearby vocabulary together. In this analysis, examples include Virus, Algae and Coronavirus. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Griffithsin
    • Virus
    • Algae
    • Coronavirus
    • Ebolavirus
    • Isolated
    • Sars
    • Tobacco
    • Bind
    • Carbohydrate
    • Glycoproteins
    • Griffithsia
    • Microbicide
  • griffithsin
    • Virus
    • Algae
    • Coronavirus
    • Ebolavirus
    • Isolated
    • Sars
    • Tobacco
    • Bind
    • Carbohydrate
    • Glycoproteins
    • Griffithsia
    • Microbicide
  • entry inhibitor
    • Potent
    • Shown
    • Vitro
    • 3ll2
    • Alga
    • Highly
    • Inhibitor
    • Sars
    • Sp
    • Griffithsia
    • Pdb
    • Red
  • griffithsia
    • Red
    • 3ll2
    • Alga
    • Isolated
    • Sp
    • Pdb
    • Protein
    • Structures
    • Entry
    • Griffithsin
  • pdb
    • Structures
    • 3ll2
    • Alga
    • Several
    • Solved
    • Sp
    • X-ray
    • Protein
    • Red
    • Entry
  • protein
    • Crystallography
    • Deposited
    • Several
    • Solved
    • X-ray
    • Pdb
    • Red
    • Structures
  • x-ray crystallography
    • Crystallography
    • Deposited
    • Several
    • Solved
    • X-ray
    • Pdb
    • Protein
    • Structures
  • red algae
    • Isolated
    • Griffithsia
    • Protein
    • Red
    • Sp
    • Structures
    • Griffithsin

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Griffithsin map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Griffithsin

Nodes20
Edges19
Triples9
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around Griffithsin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Griffithsin · EN edition · Analysis: TopicsToTalkAbout

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