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Griffithsin is a protein isolated from the red algae Griffithsia. It has a 121-amino acid sequence which exhibits a Jacalin-like lectin fold. Several structures of this protein have been solved by X-ray crystallography and deposited in the PDB. It has been shown in vitro to be a highly potent HIV entry inhibitor. It is currently being investigated as a…
The analysis highlights Standards and Overview as prominent areas in the source structure around Griffithsin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around Griffithsin shows recurring relationship patterns in the source. For example, Griffithsin → InterPro Another extracted example is Griffithsin → Griffithsia sp. (Red alga). Use these groups to spot repeated connection types before inspecting the individual relationships.
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hiv pdb entry griffithsia red protein microbicide glycoproteins shown vitro bind virus 3ll2 structures carbohydrate sp alga coronavirus sars ebolavirus
TTTA extracted 9 structured relationships around Griffithsin. Examples in this analysis include Griffithsin → Domains → InterPro and Griffithsin → Organism → Griffithsia sp. (Red alga). The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Griffithsin | Domains | InterPro | 1.00 | infobox |
| Griffithsin | Organism | Griffithsia sp. (Red alga) | 1.00 | infobox |
| Griffithsin | Orthologs | OMA: entry | 1.00 | infobox |
| Griffithsin | PDB | 3ll2More structures | 1.00 | infobox |
| Griffithsin | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Griffithsin | Structures | Swiss-model | 1.00 | infobox |
| Griffithsin | Symbol | GRFT | 1.00 | infobox |
| Griffithsin | UniProt | P84801 | 1.00 | infobox |
| Griffithsin | is a | protein isolated from the red algae Griffithsia | 0.90 | text |
The concept neighborhoods around Griffithsin bring nearby vocabulary together. In this analysis, examples include Virus, Algae and Coronavirus. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
Bridges highlight paths between different parts of the Griffithsin map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Griffithsin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Griffithsin · EN edition · Analysis: TopicsToTalkAbout