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GJB3: Function & Overview

Gap junction beta-3 protein (GJB3), also known as connexin 31 (Cx31) — is a protein that in humans is encoded by the GJB3 gene.

Language: English [EN]
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GJB3 topic overview

The analysis highlights Function and Overview as prominent areas in the source structure around GJB3.

Related topics
3
Source areas
2
Connected nodes
5
Extracted relationships
75
Related term clusters
5
Bridge connections
5

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 2 topics
Function · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
GJB3, CX31, DFNA2, DFNA2B, EKV, gap junction protein beta 3, EKVP1
Band
1p34.3 · 4 D2.2|4 61.48 cM
Bgee
skin of abdomen · skin of limb · skin of leg · skin of arm · skin of thigh
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 4 (mouse)
Databases
NCBI: entry; OMA: entry

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GJB3
3Protein · Gene · Erythrokeratodermia variabilis

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How GJB3 connects Entity context

The extracted context around GJB3 shows recurring relationship patterns in the source. For example, GJB3 → blastocyst, cervix epithelium, corneal stroma, esophagus, gingival epithelium, hair follicle, left colon, lip, morula, nipple, oral cavity, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of leg, skin of limb, skin of thigh, vulva Another extracted example is GJB3 → cell communication, cell junction, cell-cell junction, cellular response to retinoic acid, connexin complex, cytoplasm, gap junction, gap junction channel activity, in utero embryonic development, integral component of membrane, intracellular membrane-bounded organelle, membrane, placenta development, plasma membrane, skin development, spermatogenesis, transmembrane transport. Use these groups to spot repeated connection types before inspecting the individual relationships.

GJB3

Top relations

Bgee · 19
GJB3 → blastocyst, cervix epithelium, corneal stroma, esophagus, gingival epithelium, hair follicle, left colon, lip, morula, nipple, oral cavity, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of leg, skin of limb, skin of thigh, vulva
RNA expression pattern · 19
GJB3 → blastocyst, cervix epithelium, corneal stroma, esophagus, gingival epithelium, hair follicle, left colon, lip, morula, nipple, oral cavity, skin of abdomen, skin of arm, skin of back, skin of external ear, skin of leg, skin of limb, skin of thigh, vulva
Gene ontology · 17
GJB3 → cell communication, cell junction, cell-cell junction, cellular response to retinoic acid, connexin complex, cytoplasm, gap junction, gap junction channel activity, in utero embryonic development, integral component of membrane, intracellular membrane-bounded organelle, membrane, placenta development, plasma membrane, skin development, spermatogenesis, transmembrane transport
Band · 2
GJB3 → 1p34.3, 4 D2.2|4 61.48 cM
Chr. · 2
GJB3 → Chromosome 1 (human), Chromosome 4 (mouse)
End · 2
GJB3 → 127,224,637 bp, 34,786,369 bp
Aliases · 1
GJB3 → GJB3, CX31, DFNA2, DFNA2B, EKV, gap junction protein beta 3, EKVP1
BioGPS · 1
GJB3 → More reference expression data
Databases · 1
GJB3 → NCBI: entry; OMA: entry
Ensembl · 1
GJB3 → ENSG00000188910

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr protein human band gap chromosome junction external connexin location mouse cx31 function encoded 786 369 end 34

GJB3 relationships Subject–Predicate–Object triples

TTTA extracted 75 structured relationships around GJB3. Examples in this analysis include GJB3 → Aliases → GJB3, CX31, DFNA2, DFNA2B, EKV, gap junction protein beta 3, EKVP1 and GJB3 → Band → 1p34.3. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GJB3AliasesGJB3, CX31, DFNA2, DFNA2B, EKV, gap junction protein beta 3, EKVP11.00infobox
GJB3Band1p34.31.00infobox
GJB3Band4 D2.2|4 61.48 cM1.00infobox
GJB3Bgeeskin of abdomen1.00infobox
GJB3Bgeeskin of limb1.00infobox
GJB3Bgeeskin of leg1.00infobox
GJB3Bgeeskin of arm1.00infobox
GJB3Bgeeskin of thigh1.00infobox
GJB3Bgeegingival epithelium1.00infobox
GJB3Bgeevulva1.00infobox
GJB3Bgeecervix epithelium1.00infobox
GJB3Bgeenipple1.00infobox
GJB3Bgeeoral cavity1.00infobox
GJB3Bgeelip1.00infobox
GJB3Bgeeblastocyst1.00infobox
GJB3Bgeeskin of external ear1.00infobox
GJB3Bgeecorneal stroma1.00infobox
GJB3Bgeeleft colon1.00infobox
GJB3Bgeeesophagus1.00infobox
GJB3Bgeeskin of back1.00infobox
GJB3Bgeehair follicle1.00infobox
GJB3Bgeemorula1.00infobox
GJB3BioGPSMore reference expression data1.00infobox
GJB3Chr.Chromosome 1 (human)1.00infobox
GJB3Chr.Chromosome 4 (mouse)1.00infobox
GJB3DatabasesNCBI: entry; OMA: entry1.00infobox
GJB3End34,786,369 bp1.00infobox
GJB3End127,224,637 bp1.00infobox
GJB3EnsemblENSG000001889101.00infobox
GJB3Entrez27071.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around GJB3 bring nearby vocabulary together. In this analysis, examples include Junction, External and Function. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • GJB3
    • Junction
    • External
    • Function
    • Gene
    • Protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Known
  • gjb3
    • Junction
    • External
    • Function
    • Gene
    • Protein
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Humans
    • Known
  • gene
    • Gjb3
    • Junction
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Protein
    • D2
    • End
    • External
    • Function
  • function
    • External
    • Gjb3
    • Junction
    • Location
    • Chromosome
    • Gap
    • Human
    • Reading
    • References
    • Bp
    • Chr
    • Gene
  • protein
    • Cell
    • Component
    • Molecular
    • Location
    • Human
    • Reading
    • References
    • D2
    • End
    • Entry
    • Mouse
    • Ncbi

Connections between topic areas Semantic bridges

For GJB3, one of the stronger structural bridges in this analysis connects GJB3 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
GJB3 — Overview · splits 3 ⟂ 3

Map overview Semantic statistics

GJB3

Nodes6
Edges5
Triples75
Avg. degree1.67
Density0.333333
Components1

Source & methodology

TTTA analyzes the structure around GJB3 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — GJB3 · EN edition · Analysis: TopicsToTalkAbout

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