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Fosmidomycin: Applications, Cultures & Standards

Fosmidomycin is an antibiotic that was originally isolated from culture broths of bacteria of the genus Streptomyces. It specifically inhibits DXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. It is a structural analogue of 2-C-methyl-D-erythrose 4-phosphate. It inhibits the E. coli enzyme with a KI value of 38…

Language: English [EN]
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Fosmidomycin topic overview

The analysis highlights Applications, Cultures and Standards as prominent areas in the source structure around Fosmidomycin.

Related topics
15
Source areas
2
Connected nodes
17
Extracted relationships
18
Concept neighborhoods
14
Bridge connections
17

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 9 topics
Use in malaria · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
none
CAS Number
66508-53-0 N
ChEBI
CHEBI:443725 Y
ChEMBL
ChEMBL203125 Y
ChemSpider
555 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Use in malaria

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Fosmidomycin connects Entity context

The extracted context around Fosmidomycin shows recurring relationship patterns in the source. For example, Fosmidomycin → DXP, Indeed, It, Plasmodium, The Another extracted example is Fosmidomycin → Interactive image. Use these groups to spot repeated connection types before inspecting the individual relationships.

Fosmidomycin

Top relations

related to Use in malaria · 5
Fosmidomycin → DXP, Indeed, It, Plasmodium, The
3D model (JSmol) · 1
Fosmidomycin → Interactive image
ATC code · 1
Fosmidomycin → none
CAS Number · 1
Fosmidomycin → 66508-53-0 N
ChEBI · 1
Fosmidomycin → CHEBI:443725 Y
ChEMBL · 1
Fosmidomycin → ChEMBL203125 Y
ChemSpider · 1
Fosmidomycin → 555 Y
CompTox Dashboard (EPA) · 1
Fosmidomycin → DTXSID70216712
DrugBank · 1
Fosmidomycin → DB02948 Y
Formula · 1
Fosmidomycin → C4H10NO5P

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

malaria dxp reductoisomerase enzyme inhibits coli key structural non-mevalonate pathway resistance use number antibiotic streptomyces isoprenoid mtb francisella originally isolated

Fosmidomycin relationships Subject–Predicate–Object triples

TTTA extracted 18 structured relationships around Fosmidomycin. Examples in this analysis include Fosmidomycin → 3D model (JSmol) → Interactive image and Fosmidomycin → ATC code → none. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Fosmidomycin3D model (JSmol)Interactive image1.00infobox
FosmidomycinATC codenone1.00infobox
FosmidomycinCAS Number66508-53-0 N1.00infobox
FosmidomycinChEBICHEBI:443725 Y1.00infobox
FosmidomycinChEMBLChEMBL203125 Y1.00infobox
FosmidomycinChemSpider555 Y1.00infobox
FosmidomycinCompTox Dashboard (EPA)DTXSID702167121.00infobox
FosmidomycinDrugBankDB02948 Y1.00infobox
FosmidomycinFormulaC4H10NO5P1.00infobox
FosmidomycinMolar mass183.100 g·mol−11.00infobox
FosmidomycinPubChem CID5721.00infobox
FosmidomycinUNII5829E3D9I91.00infobox
Fosmidomycinis aantibiotic that was originally isolated from culture broths of bacteria of the genus Streptomyces0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Fosmidomycin bring nearby vocabulary together. In this analysis, examples include Malaria, Number and Resistance. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Fosmidomycin
    • Malaria
    • Number
    • Resistance
    • Dxp
    • Reductoisomerase
    • Bacteria
    • Broths
    • Confer
    • Culture
    • Found
    • Genus
    • Isolated
  • fosmidomycin
    • Malaria
    • Number
    • Resistance
    • Dxp
    • Reductoisomerase
    • Bacteria
    • Broths
    • Confer
    • Culture
    • Found
    • Genus
    • Isolated
  • dxp reductoisomerase
    • Reductoisomerase
    • Resistance
    • Enzyme
    • Biosynthesis
    • Confer
    • Fosmidomycin
    • Found
    • Isoprenoid
    • Mutations
    • Several
    • Specifically
    • Coli
  • e. coli
    • Confer
    • Found
    • Francisella
    • Ki
    • Mtb
    • Mutations
    • Nm
    • Several
    • Value
    • Inhibits
    • Resistance
    • Dxp
  • use in malaria
    • Number
    • Key
    • Non-mevalonate
    • Pathway
    • Structural
    • Malaria
    • Use
    • Resistance
    • Fosmidomycin
    • Reductoisomerase
  • non-mevalonate pathway
    • Pathway
    • Biosynthesis
    • Isoprenoid
    • Specifically
    • Use
    • Number
    • Structural
    • Malaria
    • Reductoisomerase
  • antibiotic
    • Bacteria
    • Broths
    • Culture
    • Genus
    • Isolated
    • Originally
    • Streptomyces
    • Fosmidomycin
  • streptomyces
    • Antibiotic
    • Bacteria
    • Broths
    • Culture
    • Genus
    • Isolated
    • Originally
    • Fosmidomycin

Connections between topic areas Semantic bridges

For Fosmidomycin, one of the stronger structural bridges in this analysis connects Fosmidomycin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FosmidomycinOverview · splits 8 ⟂ 10
FosmidomycinUse in malaria · splits 11 ⟂ 7

Map overview Semantic statistics

Fosmidomycin

Nodes18
Edges17
Triples18
Avg. degree1.89
Density0.111111
Components1

Source & methodology

TTTA analyzes the structure around Fosmidomycin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Cultures & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Fosmidomycin · EN edition · Analysis: TopicsToTalkAbout

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