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Fosmidomycin

Fosmidomycin is an antibiotic that was originally isolated from culture broths of bacteria of the genus Streptomyces. It specifically inhibits DXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. It is a structural analogue of 2-C-methyl-D-erythrose 4-phosphate. It inhibits the E. coli enzyme with a KI value of 38…

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Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
none
CAS Number
66508-53-0 N
ChEBI
CHEBI:443725 Y
ChEMBL
ChEMBL203125 Y
ChemSpider
555 Y

Topics to explore

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Overview

Use in malaria

Advanced semantic analysis

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Map overview Semantic statistics

Fosmidomycin

Nodes18
Edges17
Triples18
Avg. degree1.89
Density0.111111
Components1

How this topic connects Entity context

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Fosmidomycin

Top relations

related to Use in malaria · 5
Fosmidomycin → DXP, Indeed, It, Plasmodium, The
3D model (JSmol) · 1
Fosmidomycin → Interactive image
ATC code · 1
Fosmidomycin → none
CAS Number · 1
Fosmidomycin → 66508-53-0 N
ChEBI · 1
Fosmidomycin → CHEBI:443725 Y
ChEMBL · 1
Fosmidomycin → ChEMBL203125 Y
ChemSpider · 1
Fosmidomycin → 555 Y
CompTox Dashboard (EPA) · 1
Fosmidomycin → DTXSID70216712
DrugBank · 1
Fosmidomycin → DB02948 Y
Formula · 1
Fosmidomycin → C4H10NO5P

Important terminology Word statistics

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Important terminology

malaria dxp reductoisomerase enzyme inhibits coli key structural non-mevalonate pathway resistance use number antibiotic streptomyces isoprenoid mtb francisella originally isolated

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fosmidomycin3D model (JSmol)Interactive image1.00infobox
FosmidomycinATC codenone1.00infobox
FosmidomycinCAS Number66508-53-0 N1.00infobox
FosmidomycinChEBICHEBI:443725 Y1.00infobox
FosmidomycinChEMBLChEMBL203125 Y1.00infobox
FosmidomycinChemSpider555 Y1.00infobox
FosmidomycinCompTox Dashboard (EPA)DTXSID702167121.00infobox
FosmidomycinDrugBankDB02948 Y1.00infobox
FosmidomycinFormulaC4H10NO5P1.00infobox
FosmidomycinMolar mass183.100 g·mol−11.00infobox
FosmidomycinPubChem CID5721.00infobox
FosmidomycinUNII5829E3D9I91.00infobox
Fosmidomycinis aantibiotic that was originally isolated from culture broths of bacteria of the genus Streptomyces0.90text

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