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Foscarnet

Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J05AD01 (WHO)
Bioavailability
NA
CAS Number
4428-95-9 N (trisodium salt)
ChEBI
CHEBI:127780 Y

Topics to explore

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Overview

Medical use

Mechanism of action

Administration

Side effects

Advanced semantic analysis

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Map overview Semantic statistics

Foscarnet

Nodes37
Edges36
Triples57
Avg. degree1.95
Density0.054054
Components1

How this topic connects Entity context

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Foscarnet

Top relations

related to Medical use · 8
Foscarnet → Clinigen, CMV, Foscavir, HIV, HSV-1, HSV-2, It, This
has effect · 6
Foscarnet → CNS, Electrolyte, Genital, It, Nephrotoxicity, Other
related to External links · 6
Foscarnet → Archived, August, Drug Information Portal, June, Medicine, National Library
related to Mechanism of action · 6
Foscarnet → CMV, DNA, However, HSV, In, UL97
Legal status · 4
Foscarnet → AU: S4 (Prescription only), CA: ℞-only, UK: POM (Prescription only), US: ℞-only
KEGG · 2
Foscarnet → D00579 Y, D02267 Y
3D model (JSmol) · 1
Foscarnet → Interactive image
AHFS/Drugs.com · 1
Foscarnet → Monograph
ATC code · 1
Foscarnet → J05AD01 (WHO)
Bioavailability · 1
Foscarnet → NA

Important terminology Word statistics

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Important terminology

medication used treat viral dna use acid name foscavir cmv antiviral polymerase formula side medical pyrophosphate drugs protein phosphonomethanoic trisodium

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Foscarnet3D model (JSmol)Interactive image1.00infobox
FoscarnetAHFS/Drugs.comMonograph1.00infobox
FoscarnetATC codeJ05AD01 (WHO)1.00infobox
FoscarnetBioavailabilityNA1.00infobox
FoscarnetCAS Number4428-95-9 N (trisodium salt)1.00infobox
FoscarnetChEBICHEBI:127780 Y1.00infobox
FoscarnetChEMBLChEMBL666 Y1.00infobox
FoscarnetChemSpider3297 Y1.00infobox
FoscarnetCompTox Dashboard (EPA)DTXSID00484781.00infobox
FoscarnetDrugBankDB00529 Y1.00infobox
FoscarnetElimination half-life3.3–6.8 hours1.00infobox
FoscarnetFormulaCH3O5P1.00infobox
FoscarnetIUPHAR/BPS54971.00infobox
FoscarnetKEGGD00579 Y1.00infobox
FoscarnetKEGGD02267 Y1.00infobox
FoscarnetLegal statusAU: S4 (Prescription only)1.00infobox
FoscarnetLegal statusCA: ℞-only1.00infobox
FoscarnetLegal statusUK: POM (Prescription only)1.00infobox
FoscarnetLegal statusUS: ℞-only1.00infobox
FoscarnetLicense dataUS DailyMed: Foscarnet1.00infobox
FoscarnetMedlinePlusa6011441.00infobox
FoscarnetMolar mass126.004 g·mol−11.00infobox
FoscarnetOther namesphosphonomethanoic acid, dihydroxyphosphinecarboxylic acid oxide1.00infobox
FoscarnetPregnancy categoryAU: B31.00infobox
FoscarnetProtein binding14–17%1.00infobox
FoscarnetPubChem CID34151.00infobox
FoscarnetRoutes of administrationIntravenous1.00infobox
FoscarnetTrade namesFoscavir, Vocarvi, others1.00infobox
FoscarnetUNII364P9RVW4X1.00infobox
Foscarnetis aconjugate base of a chemical compound with the formula HO2CPO3H20.90text

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