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Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene. Ferroportin is a transmembrane protein that transports iron from the inside of a cell to the outside of the cell. Ferroportin is the only known iron exporter.
The analysis highlights Structure, Function and Role in development as prominent areas in the source structure around Ferroportin.
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Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Ferroportin shows recurring relationship patterns in the source. For example, Ferroportin → basolateral plasma membrane, cellular iron ion homeostasis, cytoplasm, cytosol, endothelium development, ferrous iron transmembrane transporter activity, identical protein binding, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, ion transport, iron ion export across plasma membrane, iron ion homeostasis, iron ion transmembrane transport, iron ion transmembrane transporter activity, iron ion transport, lymphocyte homeostasis, membrane, multicellular organismal iron ion homeostasis, negative regulation of apoptotic process Another extracted example is Ferroportin → cardiac muscle tissue of right atrium, decidua, duodenum, epithelium of small intestine, germinal epithelium, granulocyte, ileum, jejunal mucosa, left colon, liver, medullary collecting duct, mucosa of ileum, palpebral conjunctiva, pancreatic ductal cell, spleen, stroma of bone marrow, superficial temporal artery, tibiofemoral joint, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
iron fpn gene protein human also family bp slc40a1 hepcidin chr band known chromosome cell mouse transport activity liver function
TTTA extracted 125 structured relationships around Ferroportin. Examples in this analysis include Ferroportin → Aliases → SLC40A1, IREG1, MST079, MSTP079, solute carrier family 40 member 1, MTP1, SLC11A3, FPN1, HFE4 and Ferroportin → Band → 2q32.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Ferroportin | Aliases | SLC40A1, IREG1, MST079, MSTP079, solute carrier family 40 member 1, MTP1, SLC11A3, FPN1, HFE4 | 1.00 | infobox |
| Ferroportin | Band | 2q32.2 | 1.00 | infobox |
| Ferroportin | Band | 1|1 C1.1 | 1.00 | infobox |
| Ferroportin | Bgee | pancreatic ductal cell | 1.00 | infobox |
| Ferroportin | Bgee | jejunal mucosa | 1.00 | infobox |
| Ferroportin | Bgee | mucosa of ileum | 1.00 | infobox |
| Ferroportin | Bgee | germinal epithelium | 1.00 | infobox |
| Ferroportin | Bgee | trabecular bone | 1.00 | infobox |
| Ferroportin | Bgee | decidua | 1.00 | infobox |
| Ferroportin | Bgee | cardiac muscle tissue of right atrium | 1.00 | infobox |
| Ferroportin | Bgee | palpebral conjunctiva | 1.00 | infobox |
| Ferroportin | Bgee | superficial temporal artery | 1.00 | infobox |
| Ferroportin | Bgee | duodenum | 1.00 | infobox |
| Ferroportin | Bgee | epithelium of small intestine | 1.00 | infobox |
| Ferroportin | Bgee | medullary collecting duct | 1.00 | infobox |
| Ferroportin | Bgee | stroma of bone marrow | 1.00 | infobox |
| Ferroportin | Bgee | spleen | 1.00 | infobox |
| Ferroportin | Bgee | tibiofemoral joint | 1.00 | infobox |
| Ferroportin | Bgee | left colon | 1.00 | infobox |
| Ferroportin | Bgee | granulocyte | 1.00 | infobox |
| Ferroportin | Bgee | liver | 1.00 | infobox |
| Ferroportin | Bgee | ileum | 1.00 | infobox |
| Ferroportin | BioGPS | n/a | 1.00 | infobox |
| Ferroportin | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| Ferroportin | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| Ferroportin | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Ferroportin | End | 189,583,758 bp | 1.00 | infobox |
| Ferroportin | End | 45,965,683 bp | 1.00 | infobox |
| Ferroportin | Ensembl | ENSG00000138449 | 1.00 | infobox |
| Ferroportin | Entrez | 30061 | 1.00 | infobox |
The concept neighborhoods around Ferroportin bring nearby vocabulary together. In this analysis, examples include Iron, Low and Fpn. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Ferroportin, one of the stronger structural bridges in this analysis connects Ferroportin with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Ferroportin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Function & Role in development, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Ferroportin · EN edition · Analysis: TopicsToTalkAbout