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FeMoco: Structure, Biosynthesis & Identity of the core atom

FeMoco (FeMo cofactor) or M-cluster is the primary cofactor of nitrogenase. Nitrogenase is the enzyme that catalyzes the conversion of atmospheric nitrogen molecules N2 into ammonia (NH3) through the process known as nitrogen fixation. Because it contains iron and molybdenum, the cofactor is called FeMoco. Its stoichiometry is Fe7MoS9C.

Language: English [EN]
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FeMoco topic overview

The analysis highlights Structure, Biosynthesis and Identity of the core atom as prominent areas in the source structure around FeMoco.

Related topics
32
Source areas
7
Connected nodes
39
Extracted relationships
66
Concept neighborhoods
21
Bridge connections
39

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Structure · 10 topics
Overview · 7 topics
Biosynthesis · 3 topics
Electronic properties · 3 topics
Identity of the core atom · 3 topics
Isolation · 3 topics
Substrate binding · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Biosynthesis

Identity of the core atom

Electronic properties

Substrate binding

Isolation

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How FeMoco connects Entity context

The extracted context around FeMoco shows recurring relationship patterns in the source. For example, FeMoco → Also, Crystallographic, EXAFS, Fe, Fe-Fe, Fe-Mo, Fe4S3, Fe7MoS9C, III, It, Mo, MoFe, MoFe3S3, The, The Fe-S, The FeMo, These, This, X-ray Another extracted example is FeMoco → Additionally, An, CH2, During, EPR, Fe-S, Fe6-carbide, FeMo, M-cluster, NifB, NifEN, NifH, Presumably, S-adenosyl-L-methionine, SAM, The, The NifB, X-ray. Use these groups to spot repeated connection types before inspecting the individual relationships.

FeMoco

Top relations

related to Structure · 19
FeMoco → Also, Crystallographic, EXAFS, Fe, Fe-Fe, Fe-Mo, Fe4S3, Fe7MoS9C, III, It, Mo, MoFe, MoFe3S3, The, The Fe-S, The FeMo, These, This, X-ray
related to Identity of the core atom · 18
FeMoco → Additionally, An, CH2, During, EPR, Fe-S, Fe6-carbide, FeMo, M-cluster, NifB, NifEN, NifH, Presumably, S-adenosyl-L-methionine, SAM, The, The NifB, X-ray
related to Biosynthesis · 16
FeMoco → Biosynthesis, Fe, Fe4S4, Fe7MoS9C L-cluster, For, K-cluster, Mo, MoFe, Nif, NifB, NifEN, NifS, NifU, NifV, Several, These
related to Substrate binding · 12
FeMoco → Additional, CO, CO-molecules, Fe, Fe2-Fe6-edge, FeMoco-structure, Fischer-Tropsch-type, It, MoFe-protein, Se-incorporation, The, X-ray
is a · 1
FeMoco → complicated process that requires several Nif gene products

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cofactor protein femo nitrogenase carbon fe x-ray studies nifb atom biosynthesis cluster three mofe process substrate binding iron molybdenum two

FeMoco relationships Subject–Predicate–Object triples

TTTA extracted 66 structured relationships around FeMoco. Examples in this analysis include FeMoco → is a → complicated process that requires several Nif gene products and FeMoco → related to Biosynthesis → Biosynthesis. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
FeMocois acomplicated process that requires several Nif gene products0.90text
FeMocorelated to BiosynthesisBiosynthesis0.60section
FeMocorelated to BiosynthesisNif0.60section
FeMocorelated to BiosynthesisNifS0.60section
FeMocorelated to BiosynthesisNifU0.60section
FeMocorelated to BiosynthesisFe0.60section
FeMocorelated to BiosynthesisFe4S40.60section
FeMocorelated to BiosynthesisK-cluster0.60section
FeMocorelated to BiosynthesisNifB0.60section
FeMocorelated to BiosynthesisFe7MoS9C L-cluster0.60section
FeMocorelated to BiosynthesisNifEN0.60section
FeMocorelated to BiosynthesisMoFe0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around FeMoco bring nearby vocabulary together. In this analysis, examples include Studies, Crystallographic and Nifv. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • FeMoco
    • Studies
    • Crystallographic
    • Nifv
    • Binding
    • Nitrogenase
    • X-ray
    • Carbon
    • Central
    • Confirmed
    • Geometry
    • Interstitial
    • Iron
  • femoco
    • Studies
    • Crystallographic
    • Nifv
    • Binding
    • Nitrogenase
    • X-ray
    • Carbon
    • Central
    • Confirmed
    • Geometry
    • Interstitial
    • Iron
  • cofactor
    • Femo
    • Atom
    • Nitrogenase
    • Carbon
    • Protein
    • Femoco
    • Central
    • Electron
    • Fe-s
    • Showed
    • Biosynthesis
    • Process
  • carbon monoxide
    • Femo
    • X-ray
    • Central
    • Interstitial
    • Showed
    • Cofactor
    • Nitrogenase
    • Studies
    • Femoco
    • Nitrogen
    • Also
    • Crystallographic
  • identity of the core atom
    • Carbon
    • Femo
    • Central
    • Biosynthesis
    • Cofactor
    • Fe-s
    • Fe7mos9c
    • Interstitial
    • Showed
    • Sulfide
    • Binding
    • Cluster
  • x-ray absorption fine-structure
    • Studies
    • Crystallographic
    • Carbon
    • Showed
    • Binding
    • Femoco
    • Femo
    • Central
    • Confirmed
    • Geometry
    • Structural
    • Cofactor
  • substrate binding
    • Studies
    • Structural
    • Substrate
    • X-ray
    • Femoco
    • Crystallographic
    • Fe7mos9c
    • Showed
    • Biosynthesis
    • Cluster
    • Two
    • Carbon
  • protein
    • Mofe
    • Electron
    • Process
    • Nifb
    • Confirmed
    • Crystallographic
    • Fe-s
    • Nifv
    • Sulfides
    • Two
    • Three
    • Studies

Connections between topic areas Semantic bridges

For FeMoco, one of the stronger structural bridges in this analysis connects FeMoco with Structure. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
FeMocoStructure · splits 29 ⟂ 11
FeMocoOverview · splits 32 ⟂ 8
FeMocoBiosynthesis · splits 36 ⟂ 4
FeMocoIdentity of the core atom · splits 36 ⟂ 4
FeMocoElectronic properties · splits 36 ⟂ 4
FeMocoSubstrate binding · splits 36 ⟂ 4
FeMocoIsolation · splits 36 ⟂ 4

Map overview Semantic statistics

FeMoco

Nodes40
Edges39
Triples66
Avg. degree1.95
Density0.05
Components1

Source & methodology

TTTA analyzes the structure around FeMoco to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Structure, Biosynthesis & Identity of the core atom, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — FeMoco · EN edition · Analysis: TopicsToTalkAbout

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