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Etretinate: Measurement & Standards

Etretinate (trade name Tegison) is a medication developed by Hoffmann–La Roche that was approved by the FDA in 1986 to treat severe psoriasis. It is a second-generation retinoid. It was subsequently removed from the Canadian market in 1996 and the United States market in 1998 due to the high risk of birth defects. It remains on the market in Japan as…

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Etretinate topic overview

The analysis highlights Measurement and Standards as prominent areas in the source structure around Etretinate.

Related topics
21
Source areas
4
Connected nodes
25
Extracted relationships
42
Concept neighborhoods
14
Bridge connections
25

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Pharmacology · 8 topics
Overview · 6 topics
Precautions · 4 topics
Side effects · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Drugs.com archive
ATC code
D05BB01 (WHO)
CAS Number
54350-48-0 N
ChEBI
CHEBI:4913 Y
ChEMBL
ChEMBL464 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Pharmacology

Precautions

Side effects

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Etretinate connects Entity context

The extracted context around Etretinate shows recurring relationship patterns in the source. For example, Etretinate → Australia, If, In Japan, Ireland, Québec, Therefore, United Arab Emirates, United Kingdom, United States Another extracted example is Etretinate → Because, Canadian, FDA, However, In Japan, Tigason, United States. Use these groups to spot repeated connection types before inspecting the individual relationships.

Etretinate

Top relations

related to Precautions · 9
Etretinate → Australia, If, In Japan, Ireland, Québec, Therefore, United Arab Emirates, United Kingdom, United States
related to history · 7
Etretinate → Because, Canadian, FDA, However, In Japan, Tigason, United States
Legal status · 2
Etretinate → BR: Class F4 (Other prohibited substances), US: Withdrawn
related to Pharmacology · 2
Etretinate → It, While
3D model (JSmol) · 1
Etretinate → Interactive image
AHFS/Drugs.com · 1
Etretinate → Drugs.com archive
ATC code · 1
Etretinate → D05BB01 (WHO)
CAS Number · 1
Etretinate → 54350-48-0 N
ChEBI · 1
Etretinate → CHEBI:4913 Y
ChEMBL · 1
Etretinate → ChEMBL464 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

birth market half-life years defects tigason therapy fda 1996 united states due risk japan acitretin effects withdrawn elimination trade name

Etretinate relationships Subject–Predicate–Object triples

TTTA extracted 42 structured relationships around Etretinate. Examples in this analysis include Etretinate → 3D model (JSmol) → Interactive image and Etretinate → AHFS/Drugs.com → Drugs.com archive. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Etretinate3D model (JSmol)Interactive image1.00infobox
EtretinateAHFS/Drugs.comDrugs.com archive1.00infobox
EtretinateATC codeD05BB01 (WHO)1.00infobox
EtretinateCAS Number54350-48-0 N1.00infobox
EtretinateChEBICHEBI:4913 Y1.00infobox
EtretinateChEMBLChEMBL464 Y1.00infobox
EtretinateChemSpider4445538 Y1.00infobox
EtretinateCompTox Dashboard (EPA)DTXSID00230361.00infobox
EtretinateDrugBankDB00926 Y1.00infobox
EtretinateECHA InfoCard100.053.7271.00infobox
EtretinateElimination half-life120 days1.00infobox
EtretinateFormulaC23H30O31.00infobox
EtretinateIUPHAR/BPS75991.00infobox
EtretinateKEGGD00316 Y1.00infobox
EtretinateLegal statusBR: Class F4 (Other prohibited substances)1.00infobox
EtretinateLegal statusUS: Withdrawn1.00infobox
EtretinateMedlinePlusa6010101.00infobox
EtretinateMetabolitesFree acid, Z-form, chain shortening1.00infobox
EtretinateMolar mass354.490 g·mol−11.00infobox
EtretinateProtein binding>99%1.00infobox
EtretinatePubChem CID52823751.00infobox
EtretinateRoutes of administrationOral1.00infobox
EtretinateTrade namesTigason, formerly Tegison1.00infobox
EtretinateUNII65M2UDR9AG1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Etretinate bring nearby vocabulary together. In this analysis, examples include Half-life, Acitretin and Fda. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Etretinate
    • Half-life
    • Acitretin
    • Fda
    • Approved
    • Ethyl
    • Lipophilic
    • Name
    • Prohibited
    • Psoriasis
    • Severe
    • Side
    • Tegison
  • etretinate
    • Half-life
    • Acitretin
    • Fda
    • Approved
    • Ethyl
    • Lipophilic
    • Name
    • Prohibited
    • Psoriasis
    • Severe
    • Side
    • Tegison
  • elimination half-life
    • Half-life
    • Withdrawn
    • Lipophilic
    • Prohibited
    • Acitretin
    • Ethyl
    • Name
    • Retinoid
    • Side
    • Tegison
    • Trade
    • Long
  • side effects
    • Side
    • Drugs
    • Ethyl
    • Lipophilic
    • Prohibited
    • Retinoid
    • Tegison
    • Trade
    • Elimination
    • Name
    • Psoriasis
    • Severe
  • birth defects
    • Defects
    • Risk
    • High
    • Due
    • States
    • United
    • Therapy
    • Years
    • Teratogen
    • Canadian
    • Etretinate
    • Long
  • lipophilic
    • Prohibited
    • Name
    • Retinoid
    • Side
    • Tegison
    • Teratogen
    • Trade
    • Acitretin
    • Tigason
    • Withdrawn
    • Therapy
    • Years
  • ethyl
    • Lipophilic
    • Name
    • Prohibited
    • Retinoid
    • Side
    • Tegison
    • Trade
    • Acitretin
    • Tigason
    • Withdrawn
    • Etretinate
    • Half-life
  • canadian
    • Due
    • States
    • United
    • Market
    • High
    • Elimination
    • Risk
    • Withdrawn
    • Defects
    • Birth
    • Half-life

Connections between topic areas Semantic bridges

For Etretinate, one of the stronger structural bridges in this analysis connects Etretinate with Pharmacology. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Etretinate — Pharmacology · splits 17 ⟂ 9
Etretinate — Overview · splits 19 ⟂ 7
Etretinate — Precautions · splits 21 ⟂ 5
Etretinate — Side effects · splits 22 ⟂ 4

Map overview Semantic statistics

Etretinate

Nodes26
Edges25
Triples42
Avg. degree1.92
Density0.076923
Components1

Source & methodology

TTTA analyzes the structure around Etretinate to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Etretinate · EN edition · Analysis: TopicsToTalkAbout

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