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Etretinate

Etretinate (trade name Tegison) is a medication developed by Hoffmann–La Roche that was approved by the FDA in 1986 to treat severe psoriasis. It is a second-generation retinoid. It was subsequently removed from the Canadian market in 1996 and the United States market in 1998 due to the high risk of birth defects. It remains on the market in Japan as…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Drugs.com archive
ATC code
D05BB01 (WHO)
CAS Number
54350-48-0 N
ChEBI
CHEBI:4913 Y
ChEMBL
ChEMBL464 Y

Topics to explore

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Overview

Pharmacology

Precautions

Side effects

Advanced semantic analysis

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Map overview Semantic statistics

Etretinate

Nodes26
Edges25
Triples42
Avg. degree1.92
Density0.076923
Components1

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Etretinate

Top relations

related to Precautions · 9
Etretinate → Australia, If, In Japan, Ireland, Québec, Therefore, United Arab Emirates, United Kingdom, United States
related to history · 7
Etretinate → Because, Canadian, FDA, However, In Japan, Tigason, United States
Legal status · 2
Etretinate → BR: Class F4 (Other prohibited substances), US: Withdrawn
related to Pharmacology · 2
Etretinate → It, While
3D model (JSmol) · 1
Etretinate → Interactive image
AHFS/Drugs.com · 1
Etretinate → Drugs.com archive
ATC code · 1
Etretinate → D05BB01 (WHO)
CAS Number · 1
Etretinate → 54350-48-0 N
ChEBI · 1
Etretinate → CHEBI:4913 Y
ChEMBL · 1
Etretinate → ChEMBL464 Y

Important terminology Word statistics

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Important terminology

birth market half-life years defects tigason therapy fda 1996 united states due risk japan acitretin effects withdrawn elimination trade name

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Etretinate3D model (JSmol)Interactive image1.00infobox
EtretinateAHFS/Drugs.comDrugs.com archive1.00infobox
EtretinateATC codeD05BB01 (WHO)1.00infobox
EtretinateCAS Number54350-48-0 N1.00infobox
EtretinateChEBICHEBI:4913 Y1.00infobox
EtretinateChEMBLChEMBL464 Y1.00infobox
EtretinateChemSpider4445538 Y1.00infobox
EtretinateCompTox Dashboard (EPA)DTXSID00230361.00infobox
EtretinateDrugBankDB00926 Y1.00infobox
EtretinateECHA InfoCard100.053.7271.00infobox
EtretinateElimination half-life120 days1.00infobox
EtretinateFormulaC23H30O31.00infobox
EtretinateIUPHAR/BPS75991.00infobox
EtretinateKEGGD00316 Y1.00infobox
EtretinateLegal statusBR: Class F4 (Other prohibited substances)1.00infobox
EtretinateLegal statusUS: Withdrawn1.00infobox
EtretinateMedlinePlusa6010101.00infobox
EtretinateMetabolitesFree acid, Z-form, chain shortening1.00infobox
EtretinateMolar mass354.490 g·mol−11.00infobox
EtretinateProtein binding>99%1.00infobox
EtretinatePubChem CID52823751.00infobox
EtretinateRoutes of administrationOral1.00infobox
EtretinateTrade namesTigason, formerly Tegison1.00infobox
EtretinateUNII65M2UDR9AG1.00infobox

Related concept clusters Concept neighborhoods

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