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Eritoran

Eritoran is a synthetic lipid that inhibits the receptor TLR4. It was developed as a potential treatment for severe sepsis, an excessive inflammatory response to an infection. It failed a five year Phase III clinical trial, the results of which were published in 2013, and as of 2014 was no longer being developed.

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Explore the main themes, entities and connections around Eritoran. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Overview

16 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
none
CAS Number
185955-34-4 N 185954-98-7 (tetrasodium salt)
ChEMBL
ChEMBL501259 N
ChemSpider
5288721 N
CompTox Dashboard (EPA)
DTXSID60873217

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Overview

Advanced semantic analysis

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Map overview Semantic statistics

Eritoran

Nodes18
Edges17
Triples16
Avg. degree1.89
Density0.111111
Components1

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Eritoran

Top relations

3D model (JSmol) · 1
Eritoran → Interactive image
ATC code · 1
Eritoran → none
CAS Number · 1
Eritoran → 185955-34-4 N 185954-98-7 (tetrasodium salt)
ChEMBL · 1
Eritoran → ChEMBL501259 N
ChemSpider · 1
Eritoran → 5288721 N
CompTox Dashboard (EPA) · 1
Eritoran → DTXSID60873217
DrugBank · 1
Eritoran → DB04933 N
Formula · 1
Eritoran → C66H126N2O19P2
IUPHAR/BPS · 1
Eritoran → 4919
KEGG · 1
Eritoran → DG01426 N

Important terminology Word statistics

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Important terminology

tlr4 developed part lipid inhibits sepsis triggering defense binds salt tetrasodium receptor infection sodium pathogens synthetic potential treatment severe excessive

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Eritoran3D model (JSmol)Interactive image1.00infobox
EritoranATC codenone1.00infobox
EritoranCAS Number185955-34-4 N 185954-98-7 (tetrasodium salt)1.00infobox
EritoranChEMBLChEMBL501259 N1.00infobox
EritoranChemSpider5288721 N1.00infobox
EritoranCompTox Dashboard (EPA)DTXSID608732171.00infobox
EritoranDrugBankDB04933 N1.00infobox
EritoranFormulaC66H126N2O19P21.00infobox
EritoranIUPHAR/BPS49191.00infobox
EritoranKEGGDG01426 N1.00infobox
EritoranMolar mass1313.677 g·mol−11.00infobox
EritoranOther namesE 55641.00infobox
EritoranPubChem CID69124041.00infobox
EritoranRoutes of administrationIntravenous injection1.00infobox
EritoranUNII551541VI0Y1.00infobox
Eritoranis asynthetic lipid that inhibits the receptor TLR40.90text

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