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ER-X

ER-X is a membrane-associated receptor that is bound and activated by 17α-estradiol and 17β-estradiol and is a putative membrane estrogen receptor (mER). It shows sequence homology with ERα and ERβ and activates the MAPK/ERK pathway. The receptor is insensitive to the antiestrogen ICI-182,780 (fulvestrant).

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Overview

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Map overview Semantic statistics

ER-X

Nodes12
Edges11
Triples1
Avg. degree1.83
Density0.166667
Components1

How this topic connects Entity context

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ER-X

Top relations

is a · 1
ER-X → membrane-associated receptor that is bound and activated by 17α-estradiol and 17β-estradiol and is a putative membrane estrogen receptor

Important terminology Word statistics

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Important terminology

receptor estrogen 17α-estradiol 17β-estradiol erα erβ antiestrogen membrane-associated bound activated putative membrane mer shows sequence homology activates mapk erk pathway

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
ER-Xis amembrane-associated receptor that is bound and activated by 17α-estradiol and 17β-estradiol and is a putative membrane estrogen receptor0.90text

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