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EMX1: Telencephalic development, Function & Tissue distribution

Homeobox protein EMX1 is a protein that in humans is encoded by the EMX1 gene. The transcribed EMX1 gene is a member of the EMX family of transcription factors. The EMX1 gene, along with its family members, are expressed in the developing cerebrum (also known as the telencephalon). EMX1 plays a role in specification of positional identity, the…

Language: English [EN]
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EMX1 topic overview

The analysis highlights Telencephalic development, Function and Tissue distribution as prominent areas in the source structure around EMX1.

Related topics
20
Source areas
5
Connected nodes
25
Extracted relationships
121
Concept neighborhoods
16
Bridge connections
25

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Telencephalic development · 8 topics
Overview · 7 topics
Function · 2 topics
Tissue distribution · 2 topics
Regulation by Gli3 · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EMX1, empty spiracles homeobox 1
Band
2p13.2 · 6 C3|6 37.21 cM
Bgee
ganglionic eminence · ventricular zone · oocyte · gonad · right frontal lobe
BioGPS
More reference expression data
Chr.
Chromosome 2 (human) · Chromosome 6 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Tissue distribution

Telencephalic development

Regulation by Gli3

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EMX1 connects Entity context

The extracted context around EMX1 shows recurring relationship patterns in the source. For example, EMX1 → brain development, brain morphogenesis, cerebral cortex development, cerebral cortex neuron differentiation, cerebral cortex regionalization, cytoplasm, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, homeostasis of number of cells, in utero embryonic development, multicellular organism development, neuroepithelial cell differentiation, neuron differentiation, neuron projection extension, nucleolus, nucleus, post-embryonic development, protein binding, radial glial cell differentiation, regulation of oligodendrocyte progenitor proliferation Another extracted example is EMX1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, gonad, human kidney, oocyte, otic vesicle, prefrontal cortex, primary visual cortex, proximal tubule, renal cortex, right frontal lobe, right kidney, Subplate, superior frontal gyrus, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

EMX1

Top relations

Gene ontology · 24
EMX1 → brain development, brain morphogenesis, cerebral cortex development, cerebral cortex neuron differentiation, cerebral cortex regionalization, cytoplasm, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, homeostasis of number of cells, in utero embryonic development, multicellular organism development, neuroepithelial cell differentiation, neuron differentiation, neuron projection extension, nucleolus, nucleus, post-embryonic development, protein binding, radial glial cell differentiation, regulation of oligodendrocyte progenitor proliferation
Bgee · 18
EMX1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, gonad, human kidney, oocyte, otic vesicle, prefrontal cortex, primary visual cortex, proximal tubule, renal cortex, right frontal lobe, right kidney, Subplate, superior frontal gyrus, ventricular zone
RNA expression pattern · 18
EMX1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, ganglionic eminence, gonad, human kidney, oocyte, otic vesicle, prefrontal cortex, primary visual cortex, proximal tubule, renal cortex, right frontal lobe, right kidney, Subplate, superior frontal gyrus, ventricular zone
related to Developing forebrain · 12
EMX1 → At E9, E10, E17, Expression, For, However, MZ, SP, This, VI, VZ, While
related to Tissue distribution · 11
EMX1 → After, At, E11, E17, E9, Emx, However, Most, SP, VI, VZ
related to Role in the mouse embryo · 5
EMX1 → E9, Emx, From E9, In, This
related to Function · 4
EMX1 → Emx, Histologically, The, These
related to Regulation by Gli3 · 4
EMX1 → Emx2, Gli3, In Gli3 Extra-toes, The Gli3
related to Telencephalic development · 4
EMX1 → During, Emx2, The, These
Band · 2
EMX1 → 2p13.2, 6 C3|6 37.21 cM

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

telencephalon gene cortex developing bp expression cerebral expressed human chr band role transcription mouse development cortical neurons dorsal chromosome cells

EMX1 relationships Subject–Predicate–Object triples

TTTA extracted 121 structured relationships around EMX1. Examples in this analysis include EMX1 → Aliases → EMX1, empty spiracles homeobox 1 and EMX1 → Band → 2p13.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EMX1AliasesEMX1, empty spiracles homeobox 11.00infobox
EMX1Band2p13.21.00infobox
EMX1Band6 C3|6 37.21 cM1.00infobox
EMX1Bgeeganglionic eminence1.00infobox
EMX1Bgeeventricular zone1.00infobox
EMX1Bgeeoocyte1.00infobox
EMX1Bgeegonad1.00infobox
EMX1Bgeeright frontal lobe1.00infobox
EMX1Bgeehuman kidney1.00infobox
EMX1BgeeBrodmann area 91.00infobox
EMX1Bgeeprefrontal cortex1.00infobox
EMX1Bgeecingulate gyrus1.00infobox
EMX1Bgeeanterior cingulate cortex1.00infobox
EMX1BgeeSubplate1.00infobox
EMX1Bgeeprimary visual cortex1.00infobox
EMX1Bgeeright kidney1.00infobox
EMX1Bgeesuperior frontal gyrus1.00infobox
EMX1Bgeeotic vesicle1.00infobox
EMX1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
EMX1Bgeerenal cortex1.00infobox
EMX1Bgeeproximal tubule1.00infobox
EMX1BioGPSMore reference expression data1.00infobox
EMX1Chr.Chromosome 2 (human)1.00infobox
EMX1Chr.Chromosome 6 (mouse)1.00infobox
EMX1DatabasesNCBI: entry; OMA: entry1.00infobox
EMX1End72,936,071 bp1.00infobox
EMX1End85,181,444 bp1.00infobox
EMX1EnsemblENSG000001356381.00infobox
EMX1Entrez20161.00infobox
EMX1External IDsOMIM: 600034; MGI: 95387; GeneCards: EMX11.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around EMX1 bring nearby vocabulary together. In this analysis, examples include Gene, Developing and Cortical. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • EMX1
    • Gene
    • Developing
    • Cortical
    • Expression
    • Telencephalon
    • Role
    • Neurons
    • Expressed
    • Cortex
    • Differentiation
    • E9
    • Transcription
  • emx1
    • Gene
    • Developing
    • Cortical
    • Expression
    • Telencephalon
    • Role
    • Neurons
    • Expressed
    • Cortex
    • Differentiation
    • E9
    • Transcription
  • gene
    • Location
    • Expression
    • Chromosome
    • Mouse
    • Transcription
    • Bp
    • Chr
    • Human
    • Telencephalon
    • Function
    • Also
    • Factor
  • neural stem cells
    • Glial
    • Cell
    • Proliferation
    • Differentiation
    • Identity
    • Development
    • Cerebral
    • Function
    • Cortex
    • Factor
    • Location
    • Telencephalon
  • cell nuclei
    • Cells
    • Glial
    • Proliferation
    • Cerebral
    • Differentiation
    • Identity
    • Cortex
    • Function
    • Factor
    • Location
    • Telencephalon
    • Band
  • ventricular zone
    • However
    • Transcript
    • Cortical
    • Neurons
    • Function
    • Factor
    • Glial
    • Location
    • Proliferation
    • Emx1
    • Band
    • Brain
  • cerebral cortex
    • Cortex
    • Brain
    • Developing
    • Transcript
    • Mouse
    • Identity
    • Emx1
    • Expressed
    • Telencephalon
    • Function
    • Factor
    • Glial
  • marginal zone
    • However
    • Transcript
    • Cortical
    • Neurons
    • Function
    • Factor
    • Glial
    • Location
    • Proliferation
    • Emx1
    • Band
    • Brain

Connections between topic areas Semantic bridges

For EMX1, one of the stronger structural bridges in this analysis connects EMX1 with Telencephalic development. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EMX1Telencephalic development · splits 17 ⟂ 9
EMX1Overview · splits 18 ⟂ 8
EMX1Function · splits 23 ⟂ 3
EMX1Tissue distribution · splits 23 ⟂ 3

Map overview Semantic statistics

EMX1

Nodes26
Edges25
Triples121
Avg. degree1.92
Density0.076923
Components1

Source & methodology

TTTA analyzes the structure around EMX1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Telencephalic development, Function & Tissue distribution, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EMX1 · EN edition · Analysis: TopicsToTalkAbout

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