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Research this topic
Explore the main themes, entities and connections around KLF1. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Structure
3 related topics
Function
3 related topics
Clinical significance
1 related topics
Overview
4 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- Aliases
- KLF1, CDAN4, EKLF, HBFQTL6, INLU, Kruppel-like factor 1 (erythroid), Kruppel like factor 1, EKLF/KLF1
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2I, 2MBH, 2N23
- Band
- 19p13.13 · 8 41.3 cM|8 C3
- Bgee
- trabecular bone · bone marrow · blood · bone marrow cell · monocyte
- BioGPS
- n/a
- Chr.
- Chromosome 19 (human) · Chromosome 8 (mouse)
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
- Protein
- Gene
- Transcription factor
- Erythroid Erythrocytes
Structure
- Transactivation domain
- Chromatin
- C2H2 zinc fingers Zinc finger
Function
Clinical significance
- CDA type IV Congenital dyserythropoietic anemia
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.KLF1
Nodes16
Edges15
Triples120
Avg. degree1.88
Density0.125
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
KLF1
Top relations
related to Clinical significance · 40
KLF1 → Additional, Antigens, AnWj, Aquaporin1, Basal, CD147, CD44, CDA, Colton, Diego, Duffy, Embryonic, EMMPRIN, ERMAP, Fy, HbF, HBFQTL6, HPFH KLF1-related, In, Indian
Gene ontology · 19
KLF1 → cellular response to peptide, cis-regulatory region sequence-specific DNA binding, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, erythrocyte differentiation, maternal process involved in female pregnancy, metal ion binding, nucleic acid binding, nucleoplasm, nucleus, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription, DNA-templated
Bgee · 18
KLF1 → abdominal wall, blood, body of femur, bone marrow, bone marrow cell, embryo, female urethra, fetal liver hematopoietic progenitor cell, gonad, granulocyte, human fetus, monocyte, spleen, tibialis anterior muscle, tibiofemoral joint, trabecular bone, urethra, ventricular zone
RNA expression pattern · 18
KLF1 → abdominal wall, blood, body of femur, bone marrow, bone marrow cell, embryo, female urethra, fetal liver hematopoietic progenitor cell, gonad, granulocyte, human fetus, monocyte, spleen, tibialis anterior muscle, tibiofemoral joint, trabecular bone, urethra, ventricular zone
Band · 2
KLF1 → 19p13.13, 8 41.3 cM|8 C3
Chr. · 2
KLF1 → Chromosome 19 (human), Chromosome 8 (mouse)
End · 2
KLF1 → 12,887,201 bp, 85,631,924 bp
related to Function · 2
KLF1 → Over-expression, Studies
Aliases · 1
KLF1 → KLF1, CDAN4, EKLF, HBFQTL6, INLU, Kruppel-like factor 1 (erythroid), Kruppel like factor 1, EKLF/KLF1
Available structures · 1
KLF1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2I, 2MBH, 2N23
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
gene human bp band factor chromosome 19 chr mouse transcription blood function mutations krueppel-like erythroid location humans protein expression cell
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| KLF1 | Aliases | KLF1, CDAN4, EKLF, HBFQTL6, INLU, Kruppel-like factor 1 (erythroid), Kruppel like factor 1, EKLF/KLF1 | 1.00 | infobox |
| KLF1 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2L2I, 2MBH, 2N23 | 1.00 | infobox |
| KLF1 | Band | 19p13.13 | 1.00 | infobox |
| KLF1 | Band | 8 41.3 cM|8 C3 | 1.00 | infobox |
| KLF1 | Bgee | trabecular bone | 1.00 | infobox |
| KLF1 | Bgee | bone marrow | 1.00 | infobox |
| KLF1 | Bgee | blood | 1.00 | infobox |
| KLF1 | Bgee | bone marrow cell | 1.00 | infobox |
| KLF1 | Bgee | monocyte | 1.00 | infobox |
| KLF1 | Bgee | tibialis anterior muscle | 1.00 | infobox |
| KLF1 | Bgee | granulocyte | 1.00 | infobox |
| KLF1 | Bgee | ventricular zone | 1.00 | infobox |
| KLF1 | Bgee | gonad | 1.00 | infobox |
| KLF1 | Bgee | spleen | 1.00 | infobox |
| KLF1 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| KLF1 | Bgee | tibiofemoral joint | 1.00 | infobox |
| KLF1 | Bgee | human fetus | 1.00 | infobox |
| KLF1 | Bgee | embryo | 1.00 | infobox |
| KLF1 | Bgee | body of femur | 1.00 | infobox |
| KLF1 | Bgee | abdominal wall | 1.00 | infobox |
| KLF1 | Bgee | urethra | 1.00 | infobox |
| KLF1 | Bgee | female urethra | 1.00 | infobox |
| KLF1 | BioGPS | n/a | 1.00 | infobox |
| KLF1 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| KLF1 | Chr. | Chromosome 8 (mouse) | 1.00 | infobox |
| KLF1 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| KLF1 | End | 12,887,201 bp | 1.00 | infobox |
| KLF1 | End | 85,631,924 bp | 1.00 | infobox |
| KLF1 | Ensembl | ENSG00000105610 | 1.00 | infobox |
| KLF1 | Entrez | 10661 | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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