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DMRT1

Doublesex and mab-3 related transcription factor 1, also known as DMRT1, is a protein which in humans is encoded by the DMRT1 gene.

Structure, Function & Clinical significance

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Structure

3 related topics

Function

2 related topics

Clinical significance

2 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
DMRT1, CT154, DMT1, doublesex and mab-3 related transcription factor 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YJ0
Band
9p24.3 · 19|19 B
Bgee
gonad · testicle · buccal mucosa cell · right testis · left testis
BioGPS
More reference expression data
Chr.
Chromosome 9 (human) · Chromosome 19 (mouse)

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Overview

Structure

Function

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

DMRT1

Nodes14
Edges13
Triples125
Avg. degree1.86
Density0.142857
Components1

How this topic connects Entity context

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DMRT1

Top relations

Gene ontology · 39
DMRT1 → cell differentiation, cell morphogenesis, chromatin binding, cis-regulatory region sequence-specific DNA binding, cytoplasm, developmental process involved in reproduction, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, germ cell migration, identical protein binding, intracellular signal transduction, male germ cell proliferation, male gonad development, male sex determination, male sex differentiation, metal ion binding, multicellular organism development, negative regulation of meiotic nuclear division
Bgee · 19
DMRT1 → buccal mucosa cell, embryo, epithelium of seminiferous tubule of testis, germ cell, gonad, Gonadal ridge, left testis, male germ cell, morula, olfactory zone of nasal mucosa, placenta, right testis, seminiferous tubule, Sertoli cell, spermatid, spermatocyte, spermatogonium, testicle, thyroid gland
RNA expression pattern · 19
DMRT1 → buccal mucosa cell, embryo, epithelium of seminiferous tubule of testis, germ cell, gonad, Gonadal ridge, left testis, male germ cell, morula, olfactory zone of nasal mucosa, placenta, right testis, seminiferous tubule, Sertoli cell, spermatid, spermatocyte, spermatogonium, testicle, thyroid gland
related to External links · 12
DMRT1 → Doublesex, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Overview, PDB, PDBe-KB, Q9Y5R6, This, UniProt, United States National Library
related to Structure · 5
DMRT1 → DM, DNA-binding, Sertoli, The, The DM
related to Clinical significance · 3
DMRT1 → Defective, Loss, XY
related to Function · 3
DMRT1 → Sertoli, The, Two
Band · 2
DMRT1 → 19|19 B, 9p24.3
Chr. · 2
DMRT1 → Chromosome 19 (mouse), Chromosome 9 (human)
End · 2
DMRT1 → 25,581,693 bp, 969,090 bp

Important terminology Word statistics

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Important terminology

gene chromosome bp human factor chr band transcription sertoli germ male development cells protein location testicular end mouse cell developmental

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DMRT1AliasesDMRT1, CT154, DMT1, doublesex and mab-3 related transcription factor 11.00infobox
DMRT1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YJ01.00infobox
DMRT1Band9p24.31.00infobox
DMRT1Band19|19 B1.00infobox
DMRT1Bgeegonad1.00infobox
DMRT1Bgeetesticle1.00infobox
DMRT1Bgeebuccal mucosa cell1.00infobox
DMRT1Bgeeright testis1.00infobox
DMRT1Bgeeleft testis1.00infobox
DMRT1Bgeeolfactory zone of nasal mucosa1.00infobox
DMRT1Bgeegerm cell1.00infobox
DMRT1Bgeemale germ cell1.00infobox
DMRT1Bgeeplacenta1.00infobox
DMRT1Bgeethyroid gland1.00infobox
DMRT1BgeeGonadal ridge1.00infobox
DMRT1Bgeeseminiferous tubule1.00infobox
DMRT1Bgeeepithelium of seminiferous tubule of testis1.00infobox
DMRT1BgeeSertoli cell1.00infobox
DMRT1Bgeespermatogonium1.00infobox
DMRT1Bgeespermatid1.00infobox
DMRT1Bgeemorula1.00infobox
DMRT1Bgeeembryo1.00infobox
DMRT1Bgeespermatocyte1.00infobox
DMRT1BioGPSMore reference expression data1.00infobox
DMRT1Chr.Chromosome 9 (human)1.00infobox
DMRT1Chr.Chromosome 19 (mouse)1.00infobox
DMRT1DatabasesNCBI: entry; OMA: entry1.00infobox
DMRT1End969,090 bp1.00infobox
DMRT1End25,581,693 bp1.00infobox
DMRT1EnsemblENSG000001370901.00infobox

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